Search Results - "Mancini, Cristina"
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Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target
Published in Blood (04-08-2016)“…The importance of glutamine (Gln) metabolism in multiple myeloma (MM) cells and its potential role as a therapeutic target are still unknown, although it has…”
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The Proteasome Inhibitor Bortezomib Maintains Osteocyte Viability in Multiple Myeloma Patients by Reducing Both Apoptosis and Autophagy: A New Function for Proteasome Inhibitors
Published in Journal of bone and mineral research (01-04-2016)“…ABSTRACT Multiple myeloma (MM) is characterized by severely imbalanced bone remodeling. In this study, we investigated the potential effect of proteasome…”
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CD38 expression by plasma cells in extramedullary multiple myeloma
Published in Haematologica (Roma) (01-04-2024)Get full text
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The proteasome inhibitor bortezomib affects osteoblast differentiation in vitro and in vivo in multiple myeloma patients
Published in Blood (01-07-2007)“…The proteasome inhibitor bortezomib may increase osteoblast-related markers in multiple myeloma (MM) patients; however, its potential osteoblastic stimulatory…”
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Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment
Published in Blood (15-12-2001)“…Although osteolysis is a common complication in patients with multiple myeloma (MM), the biologic mechanisms involved in the pathogenesis of MM-induced bone…”
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Bovine pestivirus is a new alternative virus for multiple myeloma oncolytic virotherapy
Published in Journal of hematology and oncology (11-07-2020)“…The oncolytic viruses have shown promising results for the treatment of multiple myeloma. However, the use of human viruses is limited by the patients'…”
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Morphological, clinical, and molecular profiling of post-polycythemia vera accelerated/blast phase occurring with and without antecedent secondary myelofibrosis
Published in Frontiers in hematology (18-04-2024)“…Introduction Polycythemia vera (PV) is a JAK2 -mutated myeloproliferative neoplasm (MPN) characterized by clonal erythrocytosis and an intrinsic risk of…”
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Self-healing CD30- T-clonal proliferation of the tongue: report of an extremely rare case
Published in BMC oral health (15-08-2019)“…The etiology of traumatic ulcerative granulomas with stromal eosinophilia (TUGSE) is not clear, traumatic irritation having advocated as the most likely cause…”
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The anti-tumoral effect of lenalidomide is increased in vivo by hypoxia-inducible factor (HIF)-1α inhibition in myeloma cells
Published in Haematologica (Roma) (01-03-2016)Get full text
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Cutaneous localization in multiple myeloma in the context of bortezomib-based treatment: how do myeloma cells escape from the bone marrow to the skin?
Published in International journal of hematology (2017)“…The skin is a possible site of extramedullary localization in multiple myeloma (MM) patients; however, the mechanisms involved in this process are poorly…”
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De novo assembly and transcriptome analysis of contrasting sugarcane varieties
Published in PloS one (11-02-2014)“…Sugarcane is an important crop and a major source of sugar and alcohol. In this study, we performed de novo assembly and transcriptome annotation for six…”
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Tuberculosis in kindergarten and primary school, Italy, 2008-2009
Published in Emerging infectious diseases (01-03-2011)“…An outbreak of tuberculosis (TB) in Italy involved 19 schoolchildren with active TB and 43 with latent infection. The source of the outbreak was a school…”
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Taxonomically Restricted Genes Are Associated With Responses to Biotic and Abiotic Stresses in Sugarcane (Saccharum spp.)
Published in Frontiers in plant science (30-06-2022)“…Orphan genes (OGs) are protein-coding genes that are restricted to particular clades or species and lack homology with genes from other organisms, making their…”
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The Wild Sugarcane and Sorghum Kinomes: Insights Into Expansion, Diversification, and Expression Patterns
Published in Frontiers in plant science (07-07-2021)“…The protein kinase (PK) superfamily is one of the largest superfamilies in plants and the core regulator of cellular signaling. Despite this substantial…”
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A Rare Case of Systemic AL Amyloidosis with Muscle Involvement: A Misleading Diagnosis
Published in Case reports in hematology (01-01-2018)“…Muscle involvement in AL amyloidosis is a rare condition, and the diagnosis of amyloid myopathy is often delayed and underdiagnosed. Amyloid myopathy may be…”
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Gene Duplication in the Sugarcane Genome: A Case Study of Allele Interactions and Evolutionary Patterns in Two Genic Regions
Published in Frontiers in plant science (07-05-2019)“…Sugarcane ( spp.) is highly polyploid and aneuploid. Modern cultivars are derived from hybridization between and . This combination results in a genome…”
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Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis
Published in Blood (15-07-2003)“…Patients with multiple myeloma (MM) have increased bone marrow (BM) angiogenesis; however, the proangiogenic properties of myeloma cells and the mechanisms of…”
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Neurofibromatosis type I and multiple myeloma coexistence: A possible link?
Published in Hematology reports (03-04-2018)“…The association between Neurofibromatosis type I (NF1) and multiple myeloma (MM), a plasma cell, dyscrasia is very rare. Here we put to the attention of the…”
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OPG/RANKL system imbalance in a case of hepatitis C-associated osteosclerosis: the pathogenetic key?
Published in Clinical rheumatology (01-06-2005)“…Hepatitis C-associated osteosclerosis (HCAO) is an impressive example of acquired diffuse osteosclerosis in adults, recently described in ten patients infected…”
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