Search Results - "Mancikova Veronika"

Current State of CAR T-Cell Therapy in Chronic Lymphocytic Leukemia by Mancikova, Veronika, Smida, Michal

“…Chimeric antigen receptor (CAR) T-cell therapy has already achieved remarkable remissions in some difficult-to-treat patients with B-cell malignancies…”
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DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers by de Cubas, Aguirre A, Korpershoek, Esther, Inglada-Pérez, Lucia, Letouzé, Eric, Currás-Freixes, Maria, Fernández, Agustin F, Comino-Méndez, Iñaki, Schiavi, Francesca, Mancikova, Veronika, Eisenhofer, Graeme, Mannelli, Massimo, Opocher, Guiseppe, Timmers, Henri, Beuschlein, Felix, de Krijger, Ronald, Cascon, Alberto, Rodríguez-Antona, Cristina, Fraga, Mario F, Favier, Judith, Gimenez-Roqueplo, Anne-Paule, Robledo, Mercedes

“…Pheochromocytoma and paraganglioma (PPGL) are rare neuroendocrine tumors, associated with highly variable postoperative evolution. The scarcity of reliable…”
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Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in RETM918T Tumors by Mancikova Veronika, Montero-Conde, Cristina, Perales-Paton, Javier, Fernandez, Agustin, Santacana María, Jodkowska Karolina, Inglada-Píérez Lucia, Castelblanco Esmeralda, Borrego Salud, Encinas, Mario, Matias-Guiu Xavier, Fraga, Mario, Robledo, Mercedes

“…Purpose: Medullary thyroid carcinoma (MTC) is a rare disease with few genetic drivers, and the etiology specific to each known susceptibility mutation remains…”
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Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon DNA damage by Mancikova, Veronika, Pesova, Michaela, Pavlova, Sarka, Helma, Robert, Zavacka, Kristyna, Hejret, Vaclav, Taus, Petr, Hynst, Jakub, Plevova, Karla, Malcikova, Jitka, Pospisilova, Sarka

“…TP53 gene abnormalities represent the most important biomarker in chronic lymphocytic leukemia (CLL). Altered protein modifications could also influence p53…”
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DNA methylation profiling of well‐differentiated thyroid cancer uncovers markers of recurrence free survival by Mancikova, Veronika, Buj, Raquel, Castelblanco, Esmeralda, Inglada‐Pérez, Lucía, Diez, Anna, Cubas, Aguirre A., Curras‐Freixes, Maria, Maravall, Francisco Xavier, Mauricio, Didac, Matias‐Guiu, Xavier, Puig‐Domingo, Manel, Capel, Ismael, Bella, María Rosa, Lerma, Enrique, Castella, Eva, Reverter, Jordi Lluis, Peinado, Miguel Ángel, Jorda, Mireia, Robledo, Mercedes

“…Thyroid cancer is a heterogeneous disease with several subtypes characterized by cytological, histological and genetic alterations, but the involvement of…”
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Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations by Mancikova, Veronika, Cruz, Raquel, Inglada‐Pérez, Lucía, Fernández‐Rozadilla, Ceres, Landa, Iñigo, Cameselle‐Teijeiro, José, Celeiro, Catuxa, Pastor, Susana, Velázquez, Antonia, Marcos, Ricard, Andía, Victor, Álvarez‐Escolá, Cristina, Meoro, Amparo, Schiavi, Francesca, Opocher, Giuseppe, Quintela, Inés, Ansede‐Bermejo, Juan, Ruiz‐Ponte, Clara, Santisteban, Pilar, Robledo, Mercedes, Carracedo, Angel

“…Thyroid cancer is the most heritable cancer of all those not displaying typical Mendelian inheritance. However, most of the genetic factors that would explain…”
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Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro by Ledererova, Aneta, Dostalova, Lenka, Kozlova, Veronika, Peschelova, Helena, Ladungova, Adriana, Culen, Martin, Loja, Tomas, Verner, Jan, Pospisilova, Sarka, Smida, Michal, Mancikova, Veronika

“…BackgroundAnti-CD19 chimeric antigen receptor T cells (CART-19) frequently induce remissions in hemato-oncological patients with recurred and/or refractory…”
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Whole-Exome Sequencing Identifies MDH2 as a New Familial Paraganglioma Gene by Cascón, Alberto, Comino-Méndez, Iñaki, Currás-Freixes, María, de Cubas, Aguirre A., Contreras, Laura, Richter, Susan, Peitzsch, Mirko, Mancikova, Veronika, Inglada-Pérez, Lucía, Pérez-Barrios, Andrés, Calatayud, María, Azriel, Sharona, Villar-Vicente, Rosa, Aller, Javier, Setién, Fernando, Moran, Sebastian, Garcia, Juan F., Río-Machín, Ana, Letón, Rocío, Gómez-Graña, Álvaro, Apellániz-Ruiz, María, Roncador, Giovanna, Esteller, Manel, Rodríguez-Antona, Cristina, Satrústegui, Jorgina, Eisenhofer, Graeme, Urioste, Miguel, Robledo, Mercedes

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Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia by Mancikova, Veronika, Peschelova, Helena, Kozlova, Veronika, Ledererova, Aneta, Ladungova, Adriana, Verner, Jan, Loja, Tomas, Folber, Frantisek, Mayer, Jiri, Pospisilova, Sarka, Smida, Michal

“…BackgroundWhile achieving prolonged remissions in other B cell-derived malignancies, chimeric antigen receptor (CAR) T cells still underperform when injected…”
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An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility by Landa, Iñigo, Boullosa, Cesar, Inglada-Pérez, Lucía, Sastre-Perona, Ana, Pastor, Susana, Velázquez, Antonia, Mancikova, Veronika, Ruiz-Llorente, Sergio, Schiavi, Francesca, Marcos, Ricard, Malats, Nuria, Opocher, Giuseppe, Diaz-Uriarte, Ramon, Santisteban, Pilar, Valencia, Alfonso, Robledo, Mercedes

“…Papillary Thyroid Cancer (PTC) is a heterogeneous and complex disease; susceptibility to PTC is influenced by the joint effects of multiple common,…”
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Microbial environment affects innate immunity in two closely related earthworm species Eisenia andrei and Eisenia fetida by Dvořák, Jiří, Mančíková, Veronika, Pižl, Václav, Elhottová, Dana, Silerová, Marcela, Roubalová, Radka, Skanta, František, Procházková, Petra, Bilej, Martin

“…Survival of earthworms in the environment depends on their ability to recognize and eliminate potential pathogens. This work is aimed to compare the innate…”
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Abstract 4142799: Central role of LIM domain binding 3 (LDB3) protein in Tetralogy of Fallot assessed by single-nuclei multiome profiling of paediatric right ventricular samples by Gyongyosi, Mariann, Han, Emilie, Lukovic, Dominika, Hasimbegovic, Ena, White, Benjamen, Gynter, Artur, Mancikova, Veronika, Pavo, Imre, Michel-Behnke, Ina

“…Abstract only Background and aims: Tetralogy of Fallot (TOF; EC: 1565/2019) is the most common cyanotic congenital heart defect with a world-wide incidence of…”
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Monitoring of microscopic fungi community in selected bee products by Mašková, Zuzana, Kňazovická, Vladimíra, Mančíková, Veronika, Tančinová, Dana, Barboráková, Zuzana

“…Honey is a remarkably complex food with a valued place in the human diet. An important indicator of its quality is the presence of microorganisms. This study…”
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Circulating Cell-Free DNA-Based Methylation Pattern in Saliva for Early Diagnosis of Head and Neck Cancer by Birknerova, Natalia, Mancikova, Veronika, Paul, Evan David, Matyasovsky, Jan, Cekan, Pavol, Palicka, Vladimir, Parova, Helena

“…Head and neck cancer (HNC) remains one of the leading causes of mortality worldwide due to tumor diagnosis at a late stage, loco-regional aggression, and…”
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Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene by Cascón, Alberto, Comino-Méndez, Iñaki, Currás-Freixes, María, de Cubas, Aguirre A, Contreras, Laura, Richter, Susan, Peitzsch, Mirko, Mancikova, Veronika, Inglada-Pérez, Lucía, Pérez-Barrios, Andrés, Calatayud, María, Azriel, Sharona, Villar-Vicente, Rosa, Aller, Javier, Setién, Fernando, Moran, Sebastian, Garcia, Juan F, Río-Machín, Ana, Letón, Rocío, Gómez-Graña, Álvaro, Apellániz-Ruiz, María, Roncador, Giovanna, Esteller, Manel, Rodríguez-Antona, Cristina, Satrústegui, Jorgina, Eisenhofer, Graeme, Urioste, Miguel, Robledo, Mercedes

“…Disruption of the Krebs cycle is a hallmark of cancer. IDH1 and IDH2 mutations are found in many neoplasms, and germline alterations in SDH genes and FH…”
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Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis by Comino-Méndez, Iñaki, de Cubas, Aguirre A, Bernal, Carmen, Álvarez-Escolá, Cristina, Sánchez-Malo, Carolina, Ramírez-Tortosa, César L, Pedrinaci, Susana, Rapizzi, Elena, Ercolino, Tonino, Bernini, Giampaolo, Bacca, Alessandra, Letón, Rocío, Pita, Guillermoó, Alonso, María R, Leandro-García, Luis J, Gómez-Graña, Alvaro, Inglada-Pérez, Lucía, Mancikova, Veronika, Rodríguez-Antona, Cristina, Mannelli, Massimo, Robledo, Mercedes, Cascón, Alberto

“…Pheochromocytomas (PCCs) and paragangliomas (PGLs) are chromaffin-cell tumors that arise from the adrenal medulla and extra-adrenal paraganglia, respectively…”
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MicroRNA deep-sequencing reveals master regulators of follicular and papillary thyroid tumors by Mancikova, Veronika, Castelblanco, Esmeralda, Pineiro-Yanez, Elena, Perales-Paton, Javier, de Cubas, Aguirre A, Inglada-Perez, Lucia, Matias-Guiu, Xavier, Capel, Ismael, Bella, Maria, Lerma, Enrique, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, Maravall, Francisco, Mauricio, Didac, Al-Shahrour, Fatima, Robledo, Mercedes

“…MicroRNA deregulation could be a crucial event in thyroid carcinogenesis. However, current knowledge is based on studies that have used inherently biased…”
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PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics by Currás-Freixes, Maria, Piñeiro-Yañez, Elena, Montero-Conde, Cristina, Apellániz-Ruiz, María, Calsina, Bruna, Mancikova, Veronika, Remacha, Laura, Richter, Susan, Ercolino, Tonino, Rogowski-Lehmann, Natalie, Deutschbein, Timo, Calatayud, María, Guadalix, Sonsoles, Álvarez-Escolá, Cristina, Lamas, Cristina, Aller, Javier, Sastre-Marcos, Julia, Lázaro, Conxi, Galofré, Juan C, Patiño-García, Ana, Meoro-Avilés, Amparo, Balmaña-Gelpi, Judith, De Miguel-Novoa, Paz, Balbín, Milagros, Matías-Guiu, Xavier, Letón, Rocío, Inglada-Pérez, Lucía, Torres-Pérez, Rafael, Roldán-Romero, Juan M, Rodríguez-Antona, Cristina, Fliedner, Stephanie M J, Opocher, Giuseppe, Pacak, Karel, Korpershoek, Esther, de Krijger, Ronald R, Vroonen, Laurent, Mannelli, Massimo, Fassnacht, Martin, Beuschlein, Felix, Eisenhofer, Graeme, Cascón, Alberto, Al-Shahrour, Fátima, Robledo, Mercedes

“…Genetic diagnosis is recommended for all pheochromocytoma and paraganglioma (PPGL) cases, as driver mutations are identified in approximately 80% of the cases…”
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H-RAS Mutations Are Restricted to Sporadic Pheochromocytomas Lacking Specific Clinical or Pathological Features: Data From a Multi-Institutional Series by Oudijk, Lindsey, de Krijger, Ronald R, Rapa, Ida, Beuschlein, Felix, de Cubas, Aguirre A, Dei Tos, Angelo P, Dinjens, Winand N. M, Korpershoek, Esther, Mancikova, Veronika, Mannelli, Massimo, Papotti, Mauro, Vatrano, Simona, Robledo, Mercedes, Volante, Marco

“…Context: Somatic or germline mutations in up to 15 disease-causative genes are detectable in up to 50% of patients with pheochromocytoma (PCC) and…”
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Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy by Leandro-García, Luis J, Leskelä, Susanna, Jara, Carlos, Gréen, Henrik, Avall-Lundqvist, Elisabeth, Wheeler, Heather E, Dolan, M Eileen, Inglada-Perez, Lucia, Maliszewska, Agnieszka, de Cubas, Aguirre A, Comino-Méndez, Iñaki, Mancikova, Veronika, Cascón, Alberto, Robledo, Mercedes, Rodríguez-Antona, Cristina

“…Peripheral neuropathy is the dose-limiting toxicity of paclitaxel, a chemotherapeutic drug widely used to treat several solid tumors such as breast, lung, and…”
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