Search Results - "Manca, Sonia"
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Milk exosomes are bioavailable and distinct microRNA cargos have unique tissue distribution patterns
Published in Scientific reports (27-07-2018)“…Exosomes participate in cell-to-cell communication, facilitated by the transfer of RNAs, proteins and lipids from donor to recipient cells. Exosomes and their…”
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Involvement of miR-190b in Xbp1 mRNA Splicing upon Tocotrienol Treatment
Published in Molecules (Basel, Switzerland) (31-12-2020)“…We previously demonstrated that apoptosis induced by tocotrienols (γ and δT3) in HeLa cells is preceded by Ca release from the endoplasmic reticulum. This…”
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Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells
Published in Biomolecules (Basel, Switzerland) (16-11-2018)“…In hepatocytes and alcohol-metabolizing cultured cells, Golgi undergoes ethanol (EtOH)-induced disorganization. Perinuclear and organized Golgi is important in…”
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Human vascular endothelial cells transport foreign exosomes from cow's milk by endocytosis
Published in American Journal of Physiology: Cell Physiology (15-05-2016)“…Encapsulation of microRNAs in exosomes confers protection against degradation and a vehicle for shuttling of microRNAs between cells and tissues, and cellular…”
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Biological Activities of Extracellular Vesicles and Their Cargos from Bovine and Human Milk in Humans and Implications for Infants
Published in The Journal of nutrition (01-01-2017)“…Extracellular vesicles (EVs) in milk harbor a variety of compounds, including lipids, proteins, noncoding RNAs, and mRNAs. Among the various classes of EVs,…”
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The Bioavailability and Distribution of Bovine Milk Exosomes is Distinct from that of their Cargos in Mice
Published in The FASEB journal (01-04-2017)“…Abstract only Background Among extracellular vesicles, exosomes are of particular interest because of their roles in cell‐to‐cell communication, which is…”
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Bioavailability and Biodistribution of Fluorophore‐labeled Exosomes from Cow's Milk after Intravenous and Oral Administration in C57Bl/6J Mice
Published in The FASEB journal (01-04-2016)“…Abstract only Background MicroRNAs (miRNAs) play essential roles in gene regulation. We have reported that miRs are not only derived from endogenous synthesis…”
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The Role of Alcohol-Induced Golgi Fragmentation for Androgen Receptor Signaling in Prostate Cancer
Published in Molecular cancer research (01-01-2019)“…Multiple epidemiologic observations and meta-analysis clearly indicate the link between alcohol abuse and the incidence and progression of prostate cancer;…”
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In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model
Published in Gene therapy (01-05-2023)“…CRISPR-based gene editing technology represents a promising approach to deliver therapies for inherited disorders, including amyotrophic lateral sclerosis…”
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Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis
Published in Cell cycle (Georgetown, Tex.) (01-07-2014)“…Notch signaling plays a complex role in carcinogenesis, and its signaling pathway has both tumor-suppressor and oncogenic components. In this study we…”
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Oxidative stress activation of miR-125b is part of the molecular switch for Hailey-Hailey disease manifestation
Published in Experimental dermatology (01-11-2011)“…: Hailey–Hailey disease (HHD) is an autosomal dominant disorder characterized by suprabasal cutaneous cell separation (acantholysis) leading to the…”
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Lack of Evidence that CYTH2/ARNO Functions as a Direct Intracellular EGFR Activator
Published in Cell (19-05-2016)Get full text
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Loss of Notch1-dependent p21Waf1/Cip1 expression influences the Notch1 outcome in tumorigenesis
Published in Cell cycle (Georgetown, Tex.) (01-07-2014)“…Notch signaling plays a complex role in carcinogenesis, and its signaling pathway has both tumor-suppressor and oncogenic components. In this study we…”
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Loss of Notch1-dependent p21 Waf1/Cip1 expression influences the Notch1 outcome in tumorigenesis
Published in Cell cycle (Georgetown, Tex.) (01-07-2014)Get full text
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