Search Results - "Manasova, Ekaterina V."

Stress promotes RNA G-quadruplex folding in human cells by Kharel, Prakash, Fay, Marta, Manasova, Ekaterina V., Anderson, Paul J., Kurkin, Alexander V., Guo, Junjie U., Ivanov, Pavel

“…Guanine (G)-rich nucleic acids can fold into G-quadruplex (G4) structures under permissive conditions. Although many RNAs contain sequences that fold into RNA…”
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Design of gp120 HIV-1 entry inhibitors by scaffold hopping via isosteric replacements by Iusupov, Ildar R., Curreli, Francesca, Spiridonov, Evgeniy A., Markov, Pavel O., Ahmed, Shahad, Belov, Dmitry S., Manasova, Ekaterina V., Altieri, Andrea, Kurkin, Alexander V., Debnath, Asim K.

“…We present the development of alternative scaffolds and validation of their synthetic pathways as a tool for the exploration of new HIV gp120 inhibitors based…”
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Design, Synthesis, and Antiviral Activity of the Thiazole Positional Isomers of a Potent HIV‐1 Entry Inhibitor NBD‐14270 by Kurkin, Alexander V., Curreli, Francesca, Iusupov, Ildar R., Spiridonov, Evgeniy A., Ahmed, Shahad, Markov, Pavel O., Manasova, Ekaterina V., Altieri, Andrea, Debnath, Asim K.

“…The envelope glycoprotein gp120 of human immunodeficiency virus type 1 (HIV‐1) plays a critical role in virus entry to the cells by binding to the host…”
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Het(aryl)isatin to het(aryl)aminoindoline scaffold hopping: A route to selective inhibitors of matrix metalloproteinases by Ivanov, Vladimir N., Agamennone, Mariangela, Iusupov, Ildar R., Laghezza, Antonio, Novoselov, Anton M., Manasova, Ekaterina V., Altieri, Andrea, Tortorella, Paolo, Shtil, Alexander A., Kurkin, Alexander V.

“…[Display omitted] Matrix metalloproteinases (MMPs) are a large family of zinc-dependent endoproteases known to exert multiple regulatory roles in tumor…”
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Front Cover: Design, Synthesis, and Antiviral Activity of the Thiazole Positional Isomers of a Potent HIV‐1 Entry Inhibitor NBD‐14270 (ChemMedChem 22/2022) by Kurkin, Alexander V., Curreli, Francesca, Iusupov, Ildar R., Spiridonov, Evgeniy A., Ahmed, Shahad, Markov, Pavel O., Manasova, Ekaterina V., Altieri, Andrea, Debnath, Asim K.

“…The Front Cover shows the interactions of the HIV‐1 envelope glycoprotein gp120 with two sets of NBD compounds (HIV‐1 entry inhibitors) representing three…”
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