Search Results - "Manarini, S."

Glycogen synthase kinase‐3 negatively regulates tissue factor expression in monocytes interacting with activated platelets by DI SANTO, A., AMORE, C., DELL'ELBA, G., MANARINI, S., EVANGELISTA, V.

“…Background: At the site of vascular injury, monocytes (MN) interacting with activated platelets (PLT) synthesize tissue factor (TF) and promote thrombus…”
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Neutrophil Activation and Hemostatic Changes in Healthy Donors Receiving Granulocyte Colony-Stimulating Factor by Falanga, A., Marchetti, M., Evangelista, V., Manarini, S., Oldani, E., Giovanelli, S., Galbusera, M., Cerletti, C., Barbui, T.

“…Granulocyte colony-stimulating factor (G-CSF) enhances neutrophil functions in vitro and in vivo. It is known that neutrophil-derived products can alter the…”
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Persistent platelet activation in patients with type 2 diabetes treated with low doses of aspirin by EVANGELISTA, V., DE BERARDIS, G., TOTANI, L., AVANZINI, F., GIORDA, C. B., BRERO, L., LEVANTESI, G., MARELLI, G., PUPILLO, M., IACUITTI, G., POZZOLI, G., DI SUMMA, P., NADA, E., DE SIMONE, G., DELL’ELBA, G., AMORE, C., MANARINI, S., PECCE, R., MAIONE, A., TOGNONI, G., NICOLUCCI, A.

“…Background:  The percentage of diabetic patients who do not benefit from the protective effect of aspirin is larger than in other populations at cardiovascular…”
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Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease by Sciulli, Maria G., Renda, Giulia, Capone, Marta L., Tacconelli, Stefania, Ricciotti, Emanuela, Manarini, Stefano, Evangelista, Virgilio, Rebuzzi, Antonio, Patrignani, Paola

“…Background and Objectives Complete and persistent suppression of platelet thromboxane (TX) A2 biosynthesis by aspirin is mandatory to fulfill its…”
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A New Class of Ibuprofen Derivatives with Reduced Gastrotoxicity by Lolli, Marco L, Cena, Clara, Medana, Claudio, Lazzarato, Loretta, Morini, Giuseppina, Coruzzi, Gabriella, Manarini, Stefano, Fruttero, Roberta, Gasco, Alberto

“…A new series of nonsteroidal antiinflammatory drugs (NSAIDs) obtained by linking ibuprofen to selected furoxan moieties and to related furazans were…”
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COX-2 is not involved in thromboxane biosynthesis by activated human platelets by Patrignani, P, Sciulli, M G, Manarini, S, Santini, G, Cerletti, C, Evangelista, V

“…The occurrence of aspirin resistance has been inferred by the assessment of platelet aggregation ex vivo in patients with ischemic vascular syndromes taking…”
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TxA2‐mediated myocardial ischemia as a consequence of an acute lung inflammatory reaction in the rabbit by Evangelista, V., Dell'elba, G., Celardo, A., Manarini, S., Cerletti, C.

“…Epidemiological studies link acute infection of the respiratory tract to a transient increased risk of acute myocardial infarction. The underlying mechanisms…”
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Role of P‐selectin, β2‐integrins, and Src tyrosine kinases in mouse neutrophil–platelet adhesion by Evangelista, V., Manarini, S., Coller, B. S., Smyth, S. S.

“…Background: The initial interaction of human polymorphonuclear leukocytes (PMN) with activated human platelets is mediated by P‐selectin and its leukocyte…”
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De Novo Synthesis of Cyclooxygenase-1 Counteracts the Suppression of Platelet Thromboxane Biosynthesis by Aspirin by Evangelista, Virgilio, Manarini, Stefano, Di Santo, Angelo, Capone, Marta L, Ricciotti, Emanuela, Di Francesco, Luigia, Tacconelli, Stefania, Sacchetti, Andrea, D’Angelo, Sandra, Scilimati, Antonio, Sciulli, Maria G, Patrignani, Paola

“…Aspirin affords cardioprotection through the acetylation of serine in human cyclooxygenase-1 (COX-1) of anucleated platelets, inducing a permanent defect in…”
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Clopidogrel inhibits platelet-leukocyte adhesion and platelet-dependent leukocyte activation by Evangelista, Virgilio, Manarini, Stefano, Dell'Elba, Giuseppe, Martelli, Nicola, Napoleone, Emanuela, Di Santo, Angelomaria, Lorenzet, Pierre Savi Roberto

“…Clopidogrel is considered to be an important therapeutic advance in anti-platelet therapy. We investigated whether inhibition by clopidogrel results in a…”
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Platelet/polymorphonuclear leukocyte interaction in dynamic conditions: evidence of adhesion cascade and cross talk between P-selectin and the beta 2 integrin CD11b/CD18 by Evangelista, V, Manarini, S, Rotondo, S, Martelli, N, Polischuk, R, McGregor, J L, de Gaetano, G, Cerletti, C

“…Adhesion between platelets and polymorphonuclear leukocytes (PMN) is a key event in thrombosis and inflammation. Double color fluorescence-activated cell…”
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Polymorphonuclear leukocyte activation and hemostasis in patients with essential thrombocythemia and polycythemia vera by Falanga, Anna, Marchetti, Marina, Evangelista, Virgilio, Vignoli, Alfonso, Licini, Marina, Balicco, Mara, Manarini, Stefano, Finazzi, Guido, Cerletti, Chiara, Barbui, Tiziano

“…Thrombohemorrhagic complications are a major cause of morbidity and mortality in patients with essential thrombocythemia (ET) and polycythemia vera (PV). The…”
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Platelet/Polymorphonuclear Leukocyte Interaction: P-Selectin Triggers Protein-Tyrosine Phosphorylation–Dependent CD11b/CD18 Adhesion: Role of PSGL-1 as a Signaling Molecule by Evangelista, Virgilio, Manarini, Stefano, Sideri, Rita, Rotondo, Serenella, Martelli, Nicola, Piccoli, Antonio, Totani, Licia, Piccardoni, Paola, Vestweber, Dietmar, de Gaetano, Giovanni, Cerletti, Chiara

“…Polymorphonuclear leukocyte (PMN) adhesion to activated platelets is important for the recruitment of PMN at sites of vascular damage and thrombus formation…”
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Platelet/polymorphonuclear leukocyte interaction in dynamic conditions: evidence of adhesion cascade and cross talk between P-selectin and the beta 2 integrin CD11b/CD18 by Evangelista, V, Manarini, S, Rotondo, S, Martelli, N, Polischuk, R, McGregor, JL, de Gaetano, G, Cerletti, C

“…Adhesion between platelets and polymorphonuclear leukocytes (PMN) is a key event in thrombosis and inflammation. Double color fluorescence- activated cell…”
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Effect of trans‐resveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte function by Rotondo, Serenella, Rajtar, Grazyna, Manarini, Stefano, Celardo, Antonio, Rotilio, Domenico, De Gaetano, Giovanni, Evangelista, Virgilio, Cerletti, Chiara

“…Polymorphonuclear leukocytes (PMN) may contribute to the pathogenesis of acute coronary heart disease (CHD). Epidemiological and laboratory evidence suggests…”
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Platelet/polymorphonuclear leukocyte interaction in dynamic conditions : Evidence of adhesion cascade and cross talk between P-selectin and the β2 integrin CD11b/CD18 by EVANGELISTA, V, MANARINI, S, ROTONDO, S, MARTELLI, N, POLISCHUK, R, MCGREGOR, J. L, DE GAETANO, G, CERLETTI, C

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Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes by CERLETTI, Chiara, DELL'ELBA, Giuseppe, MANARINI, Stefano, PECCE, Romina, DI CASTELNUOVO, Augusto, SCORPIGLIONE, Nicola, FELIZIANI, Vincenzo, DE GAETANO, Giovanni

“…Meta-analyses of the prevention of major vascular events by aspirin suggest therapeutic equivalence of all dosages. However, the optimal dosage still remains…”
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Platelet/polymorphonuclear leukocyte adhesion: a new role for SRC kinases in Mac-1 adhesive function triggered by P-selectin by Piccardoni, Paola, Sideri, Rita, Manarini, Stefano, Piccoli, Antonio, Martelli, Nicola, de Gaetano, Giovanni, Cerletti, Chiara, Evangelista, Virgilio

“…Adhesion of polymorphonuclear leukocytes (PMNLs) to activated platelets requires a P-selectin–triggered, tyrosine kinase–dependent adhesiveness of Mac-1 and is…”
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Inhibition by soya isoflavones of human polymorphonuclear leukocyte function: possible relevance for the beneficial effects of soya intake by Rotondo, Serenella, Krauze-Brzósko, Katarzyna, Manarini, Stefano, Martelli, Nicola, Pecce, Romina, Evangelista, Virgilio, Benedetta Donati, Maria, Cerletti, Chiara

“…Lower CVD incidence is reported in Asian populations consuming soya-containing food. As polymorphonuclear leukocytes (PMN) are involved in the risk of CVD, we…”
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GLYCOGEN SYNTHASE KINASE-3 NEGATIVELY REGULATES TISSUE FACTOR EXPRESSION IN MONOCYTES INTERACTING WITH ACTIVATED PLATELETS by Di Santo, A., Amore, C., Dell'Elba, G., Manarini, S., Evangelista, V.

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