Search Results - "Manalo, Nathan A"

Impairment of fetal hematopoietic stem cell function in the absence of Fancd2 by Suzuki, Sakiko, Racine, Ronny R, Manalo, Nathan A, Cantor, Sharon B, Raffel, Glen D

“…Fanconi anemia (FA) results from mutations in the genes necessary for DNA damage repair and often leads to progressive bone marrow failure. Although the…”
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CD44 induced enhancement of phosphatase activity and calcium influx: Modifications of EGR-1 expression and cell proliferation by Racine, Ronny R, Manalo, Nathan A, Hall, Jessica M F, Dibas, Adnan, Raffel, Glen D, Mummert, Mark E

“…The purpose of this study was to investigate how CD44 impaired Akt phosphorylation, EGR-1 expression and cell proliferation. E6.1 Jurkat cells, which lack…”
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Ott1(Rbm15) Regulates p53 Levels during Oncogenic and Proliferative Stress by Suzuki, Sakiko, Manalo, Nathan A, Raffel, Glen D

“…Ott1(Rbm15) is essential for engraftment and maintaining hematopoietic stem cell (HSC) quiescence during proliferative stress; therefore we sought to establish…”
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Targeting the Mechanism of c-Mpl Exon-Inclusion through Antisense Oligonucleotides Yields a Dominant Negative Isoform by Suzuki, Sakiko, Racine, Ronny R, Manalo, Nathan A, Saini, Neeraj, Odour, Cliff, Moazami, Michael, Bailey, Jeffrey A, Watts, Jonathan K, Raffel, Glen D.

“…▪ Activating mutations of the Thrombopoietin (THPO) receptor, c-MPL, have been revealed as drivers in myeloproliferative diseases (MPDs).In addition, wildtype…”
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