Search Results - "Manadas, Bruno"

SWATH‐MS as a tool for biomarker discovery: From basic research to clinical applications by Anjo, Sandra Isabel, Santa, Cátia, Manadas, Bruno

“…In the era of quantitative proteomics, where mass spectrometry plays a pivotal role, in particular associated with the use of data‐independent acquisition, it…”
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Modulation of signaling pathways by DJ-1: An updated overview by Neves, Margarida, Grãos, Mário, Anjo, Sandra I., Manadas, Bruno

“…Efforts have been made to understand the physiological and pathological role of DJ-1, a Parkinson’s disease (PD)-associated protein, to provide new insights…”
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Stem Cell Therapy for Neonatal Hypoxic-Ischemic Encephalopathy: A Systematic Review of Preclinical Studies by Serrenho, Inês, Rosado, Miguel, Dinis, Alexandra, M Cardoso, Carla, Grãos, Mário, Manadas, Bruno, Baltazar, Graça

“…Neonatal hypoxic-ischemic encephalopathy (HIE) is an important cause of mortality and morbidity in the perinatal period. This condition results from a period…”
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Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart[S] by Martins-Marques, Tania, Anjo, Sandra Isabel, Pereira, Paulo, Manadas, Bruno, Girão, Henrique

“…The coordinated and synchronized cardiac muscle contraction relies on an efficient gap junction-mediated intercellular communication (GJIC) between…”
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Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells by Soares, Ana Rosa, Martins-Marques, Tania, Ribeiro-Rodrigues, Teresa, Ferreira, Joao Vasco, Catarino, Steve, Pinho, Maria João, Zuzarte, Monica, Isabel Anjo, Sandra, Manadas, Bruno, P.G. Sluijter, Joost, Pereira, Paulo, Girao, Henrique

“…Intercellular communication is vital to ensure tissue and organism homeostasis and can occur directly, between neighbour cells via gap junctions (GJ), or…”
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The Potential of Metabolomics in the Diagnosis of Thyroid Cancer by Coelho, Margarida, Raposo, Luis, Goodfellow, Brian J, Atzori, Luigi, Jones, John, Manadas, Bruno

“…Thyroid cancer is the most common endocrine system malignancy. However, there is still a lack of reliable and specific markers for the detection and staging of…”
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Virulence Biomarkers of Bursaphelenchus xylophilus : A Proteomic Approach by Cardoso, Joana M S, Anjo, Sandra I, Manadas, Bruno, Silva, Hugo, Abrantes, Isabel, Nakamura, Katsunori, Fonseca, Luís

“…The pinewood nematode (PWN), , one of the most serious forest pests worldwide, is considered the causal agent of the pine wilt disease (PWD). The main host…”
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Disclosing proteins in the leaves of cork oak plants associated with the immune response to Phytophthora cinnamomi inoculation in the roots: A long-term proteomics approach by Coelho, Ana Cristina, Pires, Rosa, Schütz, Gabriela, Santa, Cátia, Manadas, Bruno, Pinto, Patrícia

“…The pathological interaction between oak trees and Phytophthora cinnamomi has implications in the cork oak decline observed over the last decades in the…”
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FA-SAT ncRNA interacts with PKM2 protein: depletion of this complex induces a switch from cell proliferation to apoptosis by Ferreira, Daniela, Escudeiro, Ana, Adega, Filomena, Anjo, Sandra I., Manadas, Bruno, Chaves, Raquel

“…FA - SAT is a highly conserved satellite DNA sequence transcribed in many Bilateria species. To disclose the cellular and functional profile of FA - SAT…”
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Impact of the Secretome of Human Mesenchymal Stem Cells on Brain Structure and Animal behavior in a Rat Model of Parkinson’s Disease by Teixeira, Fábio Gabriel Rodrigues, Carvalho, Miguel M., Panchalingam, K. M., Rodrigues, Ana João, Pinheiro, Bárbara Filipa Mendes, Anjo, Sandra, Manadas, Bruno, Behie, Leo A., Sousa, Nuno, Salgado, A. J.

“…Research in the last decade strongly suggests that mesenchymal stem cell (MSC)-mediated therapeutic benefits are mainly due to their secretome, which has been…”
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Chronic stress causes striatal disinhibition mediated by SOM-interneurons in male mice by Rodrigues, Diana, Jacinto, Luis, Falcão, Margarida, Castro, Ana Carolina, Cruz, Alexandra, Santa, Cátia, Manadas, Bruno, Marques, Fernanda, Sousa, Nuno, Monteiro, Patricia

“…Chronic stress (CS) is associated with a number of neuropsychiatric disorders, and it may also contribute to or exacerbate motor function. However, the…”
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Hypothermia Does Not Boost the Neuroprotection Promoted by Umbilical Cord Blood Cells in a Neonatal Hypoxia-Ischemia Rat Model by Serrenho, Inês, Cardoso, Carla M, Grãos, Mário, Dinis, Alexandra, Manadas, Bruno, Baltazar, Graça

“…Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of death and long-term disability in the perinatal period. Currently, therapeutic…”
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Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve by Mendes, Vera M, Coelho, Margarida, Tomé, Angelo R, Cunha, Rodrigo A, Manadas, Bruno

“…Caffeine is one of the most widely consumed psycho-stimulants. The study of the beneficial effects of caffeine consumption to decrease the risk of developing…”
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Pine wilt disease: what do we know from proteomics? by Cardoso, Joana M S, Manadas, Bruno, Abrantes, Isabel, Robertson, Lee, Arcos, Susana C, Troya, Maria Teresa, Navas, Alfonso, Fonseca, Luís

“…Pine wilt disease (PWD) is a devastating forest disease caused by the pinewood nematode (PWN), Bursaphelenchus xylophilus, a migratory endoparasite that…”
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Proteomics Reveals mRNA Regulation and the Action of Annexins in Thyroid Cancer by Coelho, Margarida, Capela, João, Anjo, Sandra I, Pacheco, João, Fernandes, Margarida Sá, Amendoeira, Isabel, Jones, John G, Raposo, Luís, Manadas, Bruno

“…Differentiated thyroid cancer is the most common malignancy of the endocrine system. Although most thyroid nodules are benign, given the high incidence of…”
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Systematic Review and Meta-Analysis on MS-Based Proteomics Applied to Human Peripheral Fluids to Assess Potential Biomarkers of Bipolar Disorder by Rodrigues, Joao E, Martinho, Ana, Santos, Vítor, Santa, Catia, Madeira, Nuno, Martins, Maria J, Pato, Carlos N, Macedo, Antonio, Manadas, Bruno

“…Bipolar disorder (BD) is a clinically heterogeneous condition, presenting a complex underlying etiopathogenesis that is not sufficiently characterized. Without…”
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Co-Transplantation of Adipose Tissue-Derived Stromal Cells and Olfactory Ensheathing Cells for Spinal Cord Injury Repair by Gomes, Eduardo D., Mendes, Sofia Silva, Silva, Rita Catarina Assunção Ribeiro, Teixeira, Fábio Gabriel Rodrigues, Pires, Ana O., Anjo, Sandra I., Manadas, Bruno, Leite-Almeida, Hugo, Gimble, Jeffrey M., Sousa, Nuno, Lepore, Angelo C., Silva, Nuno André Martins, Salgado, A. J.

“…Patients suffering from spinal cord injury (SCI) still have a dismal prognosis. Despite all the efforts developed in this area, currently there are no…”
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Peptidomics Unveils Distinct Acetylation Patterns of Histone and Annexin A1 in Differentiated Thyroid Cancer by Coelho, Margarida, Capela, João, Mendes, Vera M, Pacheco, João, Fernandes, Margarida Sá, Amendoeira, Isabel, Jones, John G, Raposo, Luís, Manadas, Bruno

“…Thyroid cancer is a common malignancy of the endocrine system. Nodules are routinely evaluated for malignancy risk by fine needle aspiration biopsy (FNAB), and…”
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Systematic Review and Meta-Analysis of Mass Spectrometry Proteomics Applied to Human Peripheral Fluids to Assess Potential Biomarkers of Schizophrenia by Rodrigues, João E, Martinho, Ana, Santa, Catia, Madeira, Nuno, Coroa, Manuel, Santos, Vítor, Martins, Maria J, Pato, Carlos N, Macedo, Antonio, Manadas, Bruno

“…Mass spectrometry (MS)-based techniques can be a powerful tool to identify neuropsychiatric disorder biomarkers, improving prediction and diagnosis ability…”
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Modulation of the mesenchymal stem cell secretome using computer-controlled bioreactors: impact on neuronal cell proliferation, survival and differentiation by Teixeira, Fábio Gabriel Rodrigues, Panchalingam, Krishna M., Silva, Rita Catarina Assunção Ribeiro, Serra, Sofia Cravino, Pinheiro, Bárbara Filipa Mendes, Patrício, P., Jung, Sunghoon, Anjo, Sandra I., Manadas, Bruno, Pinto, Luísa, Sousa, Nuno, Behie, Leo A., Salgado, A. J.

“…In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/ stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly…”
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