Search Results - "Manabe, Tomohiro"

Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice by Yasumatsu, Keiko, Manabe, Tomohiro, Yoshida, Ryusuke, Iwatsuki, Ken, Uneyama, Hisayuki, Takahashi, Ichiro, Ninomiya, Yuzo

“…Key points The taste receptor T1R1 + T1R3 heterodimer and metabotropic glutamate receptors (mGluR) may function as umami taste receptors. Here, we used mGluR4…”
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Use of nutritional supplements by elite Japanese track and field athletes by Tabata, Shogo, Yamasawa, Fumihiro, Torii, Suguru, Manabe, Tomohiro, Kamada, Hiroshi, Namba, Akira, Kato, Jo, Kaneko, Haruka, Tahara, Keitaro, Tsukahara, Yuka, Sato, Kazuki

“…Background While scientific evidence supports the efficacy of only limited nutritional supplements (NS) on sports performance, the use of NS is widespread in…”
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Bone marrow-derived regenerated cardiomyocytes (CMG cells) express functional adrenergic and muscarinic receptors by HAKUNO, Daihiko, FUKUDA, Keiichi, MAKINO, Shinji, KONISHI, Fusako, TOMITA, Yuichi, MANABE, Tomohiro, SUZUKI, Yusuke, UMEZAWA, Akihiro, OGAWA, Satoshi

“…We recently reported that cardiomyocytes could be differentiated from bone marrow mesenchymal stem cells in vitro by 5-azacytidine treatment. In native…”
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Oral Sildenafil Improves Primary Pulmonary Hypertension Refractory to Epoprostenol by Kataoka, Masaharu, Satoh, Toru, Manabe, Tomohiro, Anzai, Toshihisa, Yoshikawa, Tsutomu, Mitamura, Hideo, Ogawa, Satoshi

“…Background Epoprostenol (prostaglandin I2) has become recognized as a therapeutic breakthrough that can improve hemodynamics and survival in patients with…”
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A novel cardiac hypertrophic factor, neurotrophin-3, is paradoxically downregulated in cardiac hypertrophy by Kawaguchi-Manabe, Haruko, Ieda, Masaki, Kimura, Kensuke, Manabe, Tomohiro, Miyatake, Satoru, Kanazawa, Hideaki, Kawakami, Takashi, Ogawa, Satoshi, Suematsu, Makoto, Fukuda, Keiichi

“…The neurotrophin family plays pivotal roles in the development of the nervous system. Recently, the role of the neurotrophin in non-neural tissue has been…”
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Sudden cardiac arrest during marathons among young, middle-aged, and senior runners by Manabe, Tomohiro, Kato, Jo, Yamasawa, Fumihiro

“…[Display omitted] There is limited evidence showing a relationship with age in the incidence of sudden cardiac arrest during exercise, which can be lethal at…”
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Role of EGF Receptor and Pyk2 in Endothelin-1-induced ERK Activation in Rat Cardiomyocytes by Kodama, Hiroaki, Fukuda, Keiichi, Takahashi, Toshiyuki, Sano, Motoaki, Kato, Takahiro, Tahara, Satoko, Hakuno, Daihiko, Sato, Toshihiko, Manabe, Tomohiro, Konishi, Fusako, Ogawa, Satoshi

“…G protein-coupled receptor (GPCR)-evoked signal transduction pathways leading to the activation of extracellular signal-regulated kinases (ERK) are quite…”
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A case of transient mid-ventricular akinesia (a variant form of Takotsubo cardiomyopathy) followed with I-123-beta-metyl-iodophenyl pentadecanoic acid and I-123-meta-iodobenzyl-guanidine myocardial scintigraphy by Moriya, Manabu, MD, Naito, Kotaro, MD, Takahashi, Masahiko, MD, Ozoe, Akiyuki, MD, Manabe, Tomohiro, MD, Hosaka, Haruhiko, MD, Suzuki, Masahiro, MD

“…Summary A 67-year-old woman without history of heart disease was admitted with chest oppression. Her electrocardiogram (ECG) at the time of admission showed ST…”
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北海道薬科大学附属薬局の将来像と今後の課題 by 野呂瀬, 崇彦, 眞鍋, 智裕, 古田, 精一, 渡辺, 一弘

“…北海道薬科大学は, 地域社会の要請に応え, 質の高い薬剤師を養成, 輩出することによって北海道の医療の発展に貢献することを目的として, 昭和49年北海道小樽市に設置された. 以来40余年に渡り地域医療を担う医療機関, 薬局を中心に, 様々な分野において, 北海道はもとより全国各地に,…”
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Prevalence of anemia and iron deficiency and its association with body mass index in elite Japanese high school long-distance runners by Tabata, Shogo, Tsukahara, Yuka, Kamada, Hiroshi, Manabe, Tomohiro, Yamasawa, Fumihiro

“…Anemia is a common condition in long-distance runners (LDRs). Recently, not only iron deficiency (ID) but also energy deficiency has been considered as a risk…”
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Characterization of Insulin-Like Growth Factor-1–Induced Activation of the JAK/STAT Pathway in Rat Cardiomyocytes by Takahashi, Toshiyuki, Fukuda, Keiichi, Pan, Jing, Kodama, Hiroaki, Sano, Motoaki, Makino, Shinji, Kato, Takahiro, Manabe, Tomohiro, Ogawa, Satoshi

“…This study was designed to investigate whether insulin-like growth factor-1 (IGF-1) transduces signaling through the Janus kinase (JAK)/signal transducers and…”
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Tolerance to Nitroglycerin Induced by Isosorbide-5-Mononitrate Infusion in Vivo by MANABE, Tomohiro, YAMAMOTO, Atsuko, SATOH, Kumi, ICHIHARA, Kazuo

“…We examined the development of tolerance to nitroglycerin (glyceryl trinitrate; GTN) in the rat when isosorbide-5-mononitrate (ISMN) or GTN was continuously…”
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Marked Improvement with Sildenafil in a Patient with Primary Pulmonary Hypertension Unresponsive to Epoprostenol by KATAOKA, Masaharu, SATOH, Toru, MANABE, Tomohiro, ANZAI, Toshihisa, YOSHIKAWA, Tsutomu, MITAMURA, Hideo, OGAWA, Satoshi

“…We report a 48-year-old woman with right heart failure due to primary pulmonary hypertension. Continuous infusion of epoprostenol (prostaglandin I2) for 1.5…”
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Regenerative medicine in cardiology by Manabe, Tomohiro, Fukuda, Keiichi

“…Emerging evidence indicates that cardiomyocytes can be regenerated from embryonic stem cells, adult mesenchymal stem cells, and cardiac side population cells…”
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The Vision and Challenges of Hokkaido Pharmaceutical University's Affiliated Pharmacy by Norose, Takahiko, Manabe, Tomohiro, Furuta, Seiichi, Watanabe, Kazuhiro

“…Hokkaido Pharmaceutical University (HPU), according to its educational mission, seeks to “develop medical professionals who contribute to community medicine”,…”
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Cloning of Hexamethylene-bis-acetamide-inducible Transcript, HEXIM1, in Human Vascular Smooth Muscle Cells by KUSUHARA, MASATOSHI, NAGASAKI, KOICHI, KIMURA, KENSUKE, MAASS, NICOLAI, MANABE, TOMOHIRO, ISHIKAWA, SHIRO, AIKAWA, MINORU, MIYAZAKI, KOJI, YAMAGUCHI, KEN

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Exercise workload of the "Fujisawa +10 exercise" program in older women by Osawa, Yusuke, Saito, Yoshinobu, Tsunekawa, Naomi, Manabe, Tomohiro, Oguma, Yuko

“…The purpose of this study was to investigate the exercise intensity of the "Fujisawa +10 exercise" program in the elderly. Seven women (aged 65 to 75 yrs old)…”
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NEW STRATEGY OF MEDICAL THERAPY TO LEFT VENTRICULAR DYSFUNCTION WITHOUT SIGNIFICANT CORONARY STENOSIS BY USING ACETYLCHOLINE PROVOCATION by Inami, Takumi, Kataoka, Masaharu, Mera, Hisaaki, Kohshoh, Hideyasu, Yanagisawa, Ryouji, Taguchi, Hiroki, Ishiguro, Haruhisa, Manabe, Tomohiro, Satoh, Tohru, Yoshino, Hideaki

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A Short Note on Proximity-based Scoring of Documents with Multiple Fields by Manabe, Tomohiro, Fujita, Sumio

“…The BM25 ranking function is one of the most well known query relevance document scoring functions and many variations of it are proposed. The BM25F function…”
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Significance of ERK cascade compared with JAK/STAT and PI3-K pathway in gp130-mediated cardiac hypertrophy by Kodama, H, Fukuda, K, Pan, J, Sano, M, Takahashi, T, Kato, T, Makino, S, Manabe, T, Murata, M, Ogawa, S

“…We compared the role of the Raf-1/mitogen-activated protein kinase/extracellular signal-regulated protein kinase (MEK)/extracellular signal-regulated protein…”
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