Search Results - "Manabe, Tadao"

Phosphoinositide 3‐kinase inhibitor (wortmannin) inhibits pancreatic cancer cell motility and migration induced by hyaluronan in vitro and peritoneal metastasis in vivo by Teranishi, Futoshi, Takahashi, Naoko, Gao, Nan, Akamo, Yoshimi, Takeyama, Hiromitsu, Manabe, Tadao, Okamoto, Takashi

“…In order to block peritoneal metastasis of pancreatic cancer cells, we have attempted to block the signal transduction pathway involving hyaluronan (HA), Src,…”
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Interleukin‐2 potentiation of cetuximab antitumor activity for epidermal growth factor receptor‐overexpressing gastric cancer xenografts through antibody‐dependent cellular cytotoxicity by Hara, Masayasu, Nakanishi, Hayao, Tsujimura, Kunio, Matsui, Makoto, Yatabe, Yasushi, Manabe, Tadao, Tatematsu, Masae

“…Cetuximab, a chimeric monoclonal antibody to epidermal growth factor receptor (EGFR), has been proved to have clinically significant antitumor activity against…”
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Activation of focal adhesion kinase enhances the adhesion and invasion of pancreatic cancer cells via extracellular signal-regulated kinase-1/2 signaling pathway activation by Sawai, Hirozumi, Okada, Yuji, Funahashi, Hitoshi, Matsuo, Yoichi, Takahashi, Hiroki, Takeyama, Hiromitsu, Manabe, Tadao

“…Interaction with integrin and focal adhesion kinase (FAK) regulates the cancer cell adhesion and invasion into extracellular matrix (ECM). In addition,…”
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The stem cell factor/c-kit receptor pathway enhances proliferation and invasion of pancreatic cancer cells by Yasuda, Akira, Sawai, Hirozumi, Takahashi, Hiroki, Ochi, Nobuo, Matsuo, Yoichi, Funahashi, Hitoshi, Sato, Mikinori, Okada, Yuji, Takeyama, Hiromitsu, Manabe, Tadao

“…The transmembrane protein c-kit is a receptor tyrosine kinase (KIT) and KIT is expressed in solid tumors and hematological malignancies such as…”
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Stem cell factor/c-kit receptor signaling enhances the proliferation and invasion of colorectal cancer cells through the PI3K/Akt pathway by YASUDA, Akira, SAWAI, Hirozumi, TAKAHASHI, Hiroki, OCHI, Nobuo, MATSUO, Yoichi, FUNAHASHI, Hitoshi, SATO, Mikinori, OKADA, Yuji, TAKEYAMA, Hiromitsu, MANABE, Tadao

“…In this study, we examined the role of c-kit receptor (KIT) signal transduction on the proliferation and invasion of colorectal cancer cells. We found that…”
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Primary sclerosing cholangitis in Japan--analysis of 192 cases by Takikawa, H, Manabe, T

“…Primary sclerosing cholangitis is very rare in Japan. The aim of the present study was to identify the characteristics of such patients in Japan. A…”
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Interleukin-1α Enhances Angiogenesis and Is Associated With Liver Metastatic Potential in Human Gastric Cancer Cell Lines by Ma, Jiachi, M.D, Sawai, Hirozumi, M.D., Ph.D, Matsuo, Yoichi, M.D., Ph.D, Ochi, Nobuo, M.D., Ph.D, Yasuda, Akira, M.D., Ph.D, Takahashi, Hiroki, M.D., Ph.D, Wakasugi, Takehiro, M.D., Ph.D, Funahashi, Hitoshi, M.D., Ph.D, Sato, Mikinori, M.D., Ph.D, Okada, Yuji, M.D., Ph.D, Takeyama, Hiromitsu, M.D., Ph.D, Manabe, Tadao, M.D., Ph.D

“…Background To better understand the underlying mechanism of liver metastasis formation in human gastric cancer, we evaluated the angiogenic capabilities of…”
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Enhanced angiogenesis due to inflammatory cytokines from pancreatic cancer cell lines and relation to metastatic potential by Matsuo, Yoichi, Sawai, Hirozumi, Funahashi, Hitoshi, Takahashi, Hiroki, Sakamoto, Masaki, Yamamoto, Minoru, Okada, Yuji, Hayakawa, Tetsushi, Manabe, Tadao

“…To investigate the mechanisms of metastasis formation in human pancreatic carcinoma, we examined the angiogenic capabilities of human pancreatic cancer cell…”
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Laparoscopic management of small bowel incarceration caused by a broad ligament defect: report of a case by Takayama, Satoru, Hirokawa, Takahisa, Sakamoto, Masaki, Takahashi, Hiroki, Yamamoto, Minoru, Sato, Mikinori, Manabe, Tadao

“…We report the case of a 94-year-old woman who presented with signs of a small bowel obstruction many years after an appendectomy. Abdominal computed tomography…”
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Limiting vein puncture to three needle passes in subclavian vein catheterization by the infraclavicular approach by Takeyama, Hiromitsu, Taniguchi, Masaaki, Sawai, Hirozumi, Funahashi, Hitoshi, Akamo, Yoshimi, Suzuki, Sadao, Manabe, Tadao

“…With central venous catheterization, each additional vein puncture raises the risk of complications. We assessed the rate of failure and complications using a…”
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Reactive lymphoid hyperplasia of the liver in a patient with colon cancer: report of two cases by Takahashi, Hiroki, Sawai, Hirozumi, Matsuo, Yoichi, Funahashi, Hitoshi, Satoh, Mikinori, Okada, Yuji, Inagaki, Hiroshi, Takeyama, Hiromitsu, Manabe, Tadao

“…Reactive lymphoid hyperplasia (RLH) of the liver is very rarely reported, and we encountered two cases of RLH of the liver in a patient with colon cancer. In…”
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Basement Membrane Proteins Play an Important Role in the Invasive Processes of Human Pancreatic Cancer Cells by Sawai, Hirozumi, M.D., Ph.D, Okada, Yuji, M.D., Ph.D, Funahashi, Hitoshi, M.D., Ph.D, Takahashi, Hiroki, MD, Ph.D, Matsuo, Yoichi, M.D., Ph.D, Yasuda, Akira, M.D., Ph.D, Ochi, Nobuo, M.D., Ph.D, Takeyama, Hiromitsu, M.D., Ph.D, Manabe, Tadao, M.D., Ph.D

“…Background The invasive interaction between cells and their matrix has important roles in tumor cell invasion. This study investigated modulation of basement…”
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Vascular endothelial growth factor-C secreted by pancreatic cancer cell line promotes lymphatic endothelial cell migration in an in vitro model of tumor lymphangiogenesis by Ochi, Nobuo, Matsuo, Yoichi, Sawai, Hirozumi, Yasuda, Akira, Takahashi, Hiroki, Sato, Mikinori, Funahashi, Hitoshi, Okada, Yuji, Manabe, Tadao

“…To investigate mechanisms underlying lymphatic node metastasis in pancreatic cancer, we examined roles of vascular endothelial growth factor-C (VEGF-C) in…”
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Current aspects of the pathophysiology of acute pancreatitis and therapeutic effects of an inflammatory cell infiltration inhibitor by Manabe, Tadao

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Over-expression of facilitative glucose transporter genes in human cancer by Yamamoto, T, Seino, Y, Fukumoto, H, Koh, G, Yano, H, Inagaki, N, Yamada, Y, Inoue, K, Manabe, T, Imura, H

“…The expression of five facilitative glucose transporter genes, GLUT1 (erythrocyte type), GLUT2 (liver type), GLUT3 (brain type), GLUT4 (muscle/fat type), and…”
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Treatment of Peritoneal Carcinomatosis Using Carboplatin-loaded Hydroxyapatite Particles by TAKEYAMA, Hiromitsu, MOHRI, Noriaki, MIZUNO, Isamu, AKAMO, Yoshimi, SAWAI, Hirozumi, MANABE, Tadao, YOTSUYANAGI, Toshihisa, NAKAMURA, Satoshi

“…The anti-tumor effects and tissue distribution of carboplatin (CBDCA) incorporated into hydroxyapatite (HAP) particles was studied. Materials and Methods:…”
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Successful paclitaxel-based chemotherapy for an alpha-fetoprotein-producing gastric cancer patient with multiple liver metastases by Takeyama, Hiromitsu, Sawai, Hirozumi, Wakasugi, Takehiro, Takahashi, Hiroki, Matsuo, Yoichi, Ochi, Nobuo, Yasuda, Akira, Sato, Mikinori, Okada, Yuji, Funahashi, Hitoshi, Akamo, Yoshimi, Manabe, Tadao

“…Alpha-fetoprotein (AFP)-producing gastric cancer is known to frequently cause multiple liver metastases and to have an extremely poor prognosis. A 64-year-old…”
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Serum markers for predicting the severity of acute pancreatitis by Manabe, Tadao, Okada, Yuji

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Glial Cell Line–Derived Neurotrophic Factor Enhances Nuclear Factor-κB Activity and Invasive Potential in Human Pancreatic Cancer Cells by Takahashi, Hiroki, Funahashi, Hitoshi, Sawai, Hirozumi, Sakamoto, Masaki, Matsuo, Yoichi, Yamamoto, Minoru, Okada, Yuji, Hayakawa, Tetsushi, Manabe, Tadao

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Alteration of integrin expression by glial cell line-derived neurotrophic factor (GDNF) in human pancreatic cancer cells by FUNAHASHI, Hitoshi, TAKEYAMA, Hiromitsu, SAWAI, Hirozumi, FURUTA, Akiyoshi, SATO, Mikinori, OKADA, Yuji, HAYAKAWA, Tetsushi, TANAKA, Moritsugu, MANABE, Tadao

“…Pancreatic cancer cells express a number of functionally active integrins that are related to their adhesive and invasive abilities. To determine whether glial…”
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