Search Results - "Man, Xueyu"
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Developing a Copper(II) Agent Based on His-146 and His-242 Residues of Human Serum Albumin Nanoparticles: Integration To Overcome Cisplatin Resistance and Inhibit the Metastasis of Nonsmall Cell Lung Cancer
Published in Journal of medicinal chemistry (14-07-2022)“…To overcome the resistance of nonsmall cell lung cancer (NSCLC) cells to cisplatin and inhibit their metastasis, we proposed to develop a Cu(II) agent based…”
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Developing a Multitargeted Anticancer Palladium(II) Agent Based on the His-242 Residue in the IIA Subdomain of Human Serum Albumin
Published in Journal of medicinal chemistry (13-07-2023)“…To obtain next-generation metal drugs that can overcome the deficiencies of platinum (Pt) drugs and treat cancer more effectively, we proposed to develop a…”
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Developing a Ruthenium(III) Complex to Trigger Gasdermin E‑Mediated Pyroptosis and an Immune Response Based on Decitabine and Liposomes: Targeting Inhibition of Gastric Tumor Growth and Metastasis
Published in Journal of medicinal chemistry (28-09-2023)“…To develop next-generation metal drugs with high efficiency and low toxicity for targeting inhibition of gastric tumor growth and metastasis, we not only…”
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Developing a Gadolinium(III) Compound Based on Apoferritin for Targeted Magnetic Resonance Imaging and Dual-Modal Therapy of Cancer
Published in Journal of medicinal chemistry (08-06-2023)“…To integrate targeted diagnosis and treatment of cancer, we proposed to develop a gadolinium (Gd) agent based on the properties of apoferritin (AFt). To this…”
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Developing a Copper(II) Isopropyl 2‑Pyridyl Ketone Thiosemicarbazone Compound Based on the IB Subdomain of Human Serum Albumin–Indomethacin Complex: Inhibiting Tumor Growth by Remodeling the Tumor Microenvironment
Published in Journal of medicinal chemistry (11-04-2024)“…To develop a next-generation metal agent and dual-agent multitargeted combination therapy, we developed a copper (Cu) compound based on the properties of the…”
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Anticancer Tetranuclear Cu(I) Complex Catalyzes a Click Reaction to Synthesize a Chemotherapeutic Agent in situ to Achieve Targeted Dual-Agent Combination Therapy for Cancer
Published in Angewandte Chemie International Edition (31-10-2024)“…To develop next-generation metal-based drugs and dual-drug combination therapy for cancer, we proposed to develop a copper (Cu) complex that exerts anticancer…”
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Developing a Rhodium(III) Complex to Reprogram the Tumor Immune and Metabolic Microenvironments: Overcoming Multidrug Resistance and Metastasis in Non-Small Cell Lung Cancer
Published in Journal of medicinal chemistry (10-10-2024)“…To effectively inhibit the growth and metastasis of non-small cell lung cancer (NSCLC) and overcome its multidrug resistance (MDR), we designed and synthesized…”
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Rational Design of a Hetero-multinuclear Gadolinium(III)-Copper(II) Complex: Integrating Magnetic Resonance Imaging, Photoacoustic Imaging, Mild Photothermal Therapy, Chemotherapy and Immunotherapy of Cancer
Published in Journal of medicinal chemistry (12-09-2024)“…For more accurate diagnosis and effective treatment of cancer, we proposed to develop a hetero-multinuclear metal complex based on the property of apoferritin…”
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Developing a Hetero-Trinuclear Erbium(III)-Copper(II) Complex Based on Apoferritin: Targeted Photoacoustic Imaging and Multimodality Therapy of Tumor
Published in Journal of medicinal chemistry (23-11-2023)“…For the integration of targeted diagnosis and treatment of tumor, we innovatively designed and synthesized a single-molecule hetero-multinuclear Er(III)-Cu(II)…”
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Anticancer Tetranuclear Cu(I) Complex Catalyzes a Click Reaction to Synthesize a Chemotherapeutic Agent in situ to Achieve Targeted Dual‐Agent Combination Therapy for Cancer
Published in Angewandte Chemie (31-10-2024)“…Abstract To develop next‐generation metal‐based drugs and dual‐drug combination therapy for cancer, we proposed to develop a copper (Cu) complex that exerts…”
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Thermal stability and decomposition behaviors of some hydrous transition metal chlorides
Published in Journal of thermal analysis and calorimetry (01-10-2019)“…In this work, the thermal stability of CuCl 2 , CoCl 2 , MnCl 2 , and their corresponding hydrates was studied by combining with calorimetry and lattice energy…”
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