Search Results - "Man, Karen"

Up‐regulation of histone methyltransferase SETDB1 by multiple mechanisms in hepatocellular carcinoma promotes cancer metastasis by Wong, Chun‐Ming, Wei, Lai, Law, Cheuk‐Ting, Ho, Daniel Wai‐Hung, Tsang, Felice Ho‐Ching, Au, Sandy Leung‐Kuen, Sze, Karen Man‐Fong, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin

“…Epigenetic deregulation plays an important role in liver carcinogenesis. Using transcriptome sequencing, we examined the expression of 591 epigenetic…”
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Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma by Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chan, Lo-Kong, Sze, Karen Man-Fong, Zhang, Xin, Cheu, Jacinth Wing-Sum, Chiu, Yung-Tuen, Lee, Joyce Man-Fong, Chan, Albert Chi-Yan, Cheung, Elaine Tin-Yan, Yau, Derek Tsz-Wai, Chia, Nam-Hung, Lo, Irene Lai-Oi, Sham, Pak-Chung, Cheung, Tan-To, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin

“…Interaction between tumor cells and immune cells in the tumor microenvironment is important in cancer development. Immune cells interact with the tumor cells…”
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Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer by Ho, Daniel Wai-Hung, Tsui, Yu-Man, Sze, Karen Man-Fong, Chan, Lo-Kong, Cheung, Tan-To, Lee, Eva, Sham, Pak-Chung, Tsui, Stephen Kwok-Wing, Lee, Terence Kin-Wah, Ng, Irene Oi-Lin

“…Hepatocellular carcinoma (HCC) is heterogeneous, rendering its current curative treatments ineffective. The emergence of single-cell genomics represents a…”
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Dysregulation of RalA signaling through dual regulatory mechanisms exerts its oncogenic functions in hepatocellular carcinoma by Tian, Lu, Zhao, Luqing, Sze, Karen Man‐Fong, Kam, Charles Shing, Ming, Vanessa Sheung‐In, Wang, Xia, Zhang, Vanilla Xin, Ho, Daniel Wai‐Hung, Cheung, Tan‐To, Chan, Lo‐Kong, Ng, Irene Oi‐Lin

“…Background and Aims Ras‐like (Ral) small guanosine triphosphatases (GTPases), RalA and RalB, are proto‐oncogenes directly downstream of Ras and cycle between…”
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Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma by Sze, Karen Man‐Fong, Ho, Daniel Wai‐Hung, Chiu, Yung‐Tuen, Tsui, Yu‐Man, Chan, Lo‐Kong, Lee, Joyce Man‐Fong, Chok, Kenneth Siu‐Ho, Chan, Albert Chi‐Yan, Tang, Chung‐Ngai, Tang, Victor Wai‐Lun, Lo, Irene Lai‐Oi, Yau, Derek Tsz‐Wai, Cheung, Tan‐To, Ng, Irene Oi‐Lin

“…Background and Aims Hepatitis B virus (HBV) integrations are common in hepatocellular carcinoma (HCC). In particular, alterations of the telomerase reverse…”
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Automated quantification of neuronal networks and single-cell calcium dynamics using calcium imaging by Patel, Tapan P., Man, Karen, Firestein, Bonnie L., Meaney, David F.

“…•We present an open-source software for semi-automated analysis of fluorescent calcium imaging.•FluoroSNNAP, Fluorescence Single Neuron and Network Analysis…”
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Children’s Appraisals of Gender Nonconformity: Developmental Pattern and Intervention by Kwan, Karen Man Wa, Shi, Sylvia Yun, Nabbijohn, A. Natisha, MacMullin, Laura N., VanderLaan, Doug P., Wong, Wang Ivy

“…Gender‐nonconforming (GN) children are often perceived less positively, which may harm their well‐being. We examined the development of such perceptions and an…”
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Loss of phosphatase and tensin homolog enhances cell invasion and migration through aKT/Sp‐1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance by Sze, Karen Man‐Fong, Wong, Kris Lai‐Ting, Chu, Glanice Kin‐Yan, Lee, Joyce Man‐Fong, Yau, Tai‐On, Oi‐Lin Ng, Irene

“…Phosphatase and tensin homolog (PTEN) is frequently inactivated in cancers and is associated with advanced stages of cancers or metastasis. However, the…”
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Ephrin-A3/EphA2 axis regulates cellular metabolic plasticity to enhance cancer stemness in hypoxic hepatocellular carcinoma by Husain, Abdullah, Chiu, Yung-Tuen, Sze, Karen Man-Fong, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Suarez, Eliana Mary Senires, Zhang, Vanilla Xin, Chan, Lo-Kong, Lee, Eva, Lee, Joyce Man-Fong, Cheung, Tan-To, Wong, Carmen Chak-Lui, Chung, Clive Yik-Sham, Ng, Irene Oi-Lin

“…The highly proliferative nature of hepatocellular carcinoma (HCC) frequently results in a hypoxic intratumoural microenvironment, which creates a therapeutic…”
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"He Did Girls' Things!" Hong Kong and Canadian Children's Reasoning About Moral Judgments of Peers' Gendered Behaviors by Kwan, Karen Man Wa, Shi, Sylvia Yun, MacMullin, Laura N., Nabbijohn, A. Natisha, Peragine, Diana E., VanderLaan, Doug P., Wong, Wang Ivy

“…Children show less positivity toward gender-nonconforming (GN) than gender-conforming (GC) peers. Yet, little is known about children's reasoning about peers…”
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S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos by Wang, Xia, Huang, Hongyang, Sze, Karen Man-Fong, Wang, Jin, Tian, Lu, Lu, Jingyi, Tsui, Yu-Man, Ma, Hoi Tang, Lee, Eva, Chen, Ao, Lee, Joyce, Wang, Ying, Yam, Judy Wai Ping, Cheung, Tan-To, Guan, Xinyuan, Ng, Irene Oi-Lin

“…Growing evidence indicates that tumour cells exhibit characteristics similar to their lineage progenitor cells. We found that S100 calcium binding protein A10…”
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LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress by Huang, Hongyang, Tsui, Yu-Man, Ho, Daniel Wai-Hung, Chung, Clive Yik-Sham, Sze, Karen Man-Fong, Lee, Eva, Cheung, Gary Cheuk-Hang, Zhang, Vanilla Xin, Wang, Xia, Lyu, Xueying, Ng, Irene Oi-Lin

“…HCC is an aggressive cancer with a poor clinical outcome. Understanding the mechanisms that drive tumor initiation is important for improving treatment…”
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Midline 1 interacting protein 1 promotes cancer metastasis through FOS-like 1-mediated matrix metalloproteinase 9 signaling in HCC by Chiu, Yung-Tuen, Husain, Abdullah, Sze, Karen Man-Fong, Ho, Daniel Wai-Hung, Suarez, Eliana Mary Senires, Wang, Xia, Lee, Eva, Ma, Hoi-Tang, Lee, Joyce Man-Fong, Chan, Lo-Kong, Ng, Irene Oi-Lin

“…Understanding the mechanisms of HCC progression and metastasis is crucial to improve early diagnosis and treatment. This study aimed to identify key molecular…”
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Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1 by Zhang, Vanilla Xin, Sze, Karen Man-Fong, Chan, Lo-Kong, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chiu, Yung-Tuen, Lee, Eva, Husain, Abdullah, Huang, Hongyang, Tian, Lu, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin

“…Controversy over the benefits of antioxidants supplements in cancers persists for long. Using hepatocellular carcinoma (HCC) as a model, we investigated the…”
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Effects of oropharyngeal exercises on the swallowing mechanism of older adults: A systematic review by Chua, Denise Mae N, Choi, Yuen-Yu, Chan, Karen Man-Kei

“…Age-related changes to the swallowing mechanism, or presbyphagia, may put older adults at a higher risk for developing diseases and dysphagia. Maintaining…”
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Modifying Puree Meals in Residential Aged Care Facilities: A Multi-Centre Feasibility and Acceptability Study by Pu, Dai, Choi, Yuen-Yu, Chan, Karen Man-Kei, Poon, May Man-Wai

“…Purees are often recommended for older adults in residential aged care facilities (RACFs) to target swallowing difficulties and nutrition. However, they lack…”
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Multimodal Integrative Genomics and Pathology Analyses in Neoadjuvant Nivolumab Treatment for Intermediate and Locally Advanced Hepatocellular Carcinoma by Cheung, Tan-To, Ho, Daniel Wai-Hung, Lyu, Shirley Xueying, Zhang, Qingyang, Tsui, Yu-Man, Yu, Tiffany Ching-Yun, Sze, Karen Man-Fong, Lee, Joyce Man-Fong, Lau, Vince Wing-hang, Chu, Edward Yin-Lun, Tsang, Simon Hing-Yin, She, Wong-Hoi, Leung, Roland Ching-Yu, Yau, Thomas Chung-Cheung, Ng, Irene Oi-Lin

“…Introduction: Immunotherapy has resulted in pathologic responses in hepatocellular carcinoma (HCC), but the benefits and molecular mechanisms of neoadjuvant…”
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Unveiling the impact of interprofessional education on shaping students' interprofessional identity and collaboration perception: a mixed-method study by He, Qing, Dizon, John Ian Wilzon T, Ganotice, Fraide A, Zheng, Binbin, Yeung, Pauline Pui Ning, Shen, Xiaoai, Ho, Lily Yuen Wah, Wong, Arkers Kwan Ching, Cheng, Franco Wing Tak, Chan, Karen Man Kei, Chan, Linda, Chan, Sarah So Ching, Chow, Amy Yin Man, Chu, Jody Kwok Pui, Chua, Denise Mae, Dung, Edwin Chung-Hin, Lee, Wei-Ning, Leung, Feona Chung Yin, Wang, Qun, Tsia, Kevin K, Vackova, Dana, Jen, Julienne, Tipoe, George L

“…Interprofessional education (IPE) has the potential to shape students' collaboration perception and interprofessional identity but remains understudied. This…”
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RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma by Ma, Wei, Sze, Karen Man-Fong, Chan, Lo Kong, Lee, Joyce Man-Fong, Wei, Larry Lai, Wong, Chun-Ming, Lee, Terence Kin-Wah, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin

“…Small Rho GTPase (Rho) and its immediate effector Rho kinase (ROCK) are reported to regulate cell survival, but the detailed molecular mechanism remains…”
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Is minimally invasive surgery superior to open surgery for treatment of lumbar spinal stenosis? A systematic review by Ka Man Ng, Karen, Pui Yin Cheung, Jason

“…Purpose: The purpose of this study is to review the updated evidence comparing outcomes between minimally invasive surgery (MIS) and conventional open surgery…”
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