Search Results - "Man, Andy W. C."

Impact of Lifestyles (Diet and Exercise) on Vascular Health: Oxidative Stress and Endothelial Function by Man, Andy W. C., Xia, Ning, Li, Huige

“…Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2 diabetes, and cardiovascular diseases. Oxidative stress and the…”
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Perivascular Adipose Tissue Oxidative Stress in Obesity by Man, Andy W. C, Zhou, Yawen, Xia, Ning, Li, Huige

“…Perivascular adipose tissue (PVAT) adheres to most systemic blood vessels in the body. Healthy PVAT exerts anticontractile effects on blood vessels and further…”
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Local enrichment of fatty acid-binding protein 4 in the pericardial cavity of cardiovascular disease patients by Elie, Atlanta G I M, Bloksgaard, Maria, Sun, Wai Y, Yang, Kangmin, Man, Andy W C, Xu, Aimin, Irmukhamedov, Akhmadjon, Riber, Lars P, Wang, Yu, De Mey, Jo G R

“…The pericardial fluid may be representative of the interstitium of the heart. The aim of this study was to discriminate in cardiovascular disease patients…”
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Circadian Rhythm: Potential Therapeutic Target for Atherosclerosis and Thrombosis by Man, Andy W C, Li, Huige, Xia, Ning

“…Every organism has an intrinsic biological rhythm that orchestrates biological processes in adjusting to daily environmental changes. Circadian rhythms are…”
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The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging by Man, Andy W. C., Li, Huige, Xia, Ning

“…Sirtuin1 (SIRT1), which belongs to a highly conserved family of protein deacetylase, is one of the best-studied sirtuins. SIRT1 is involved in a variety of…”
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The roles of gut microbiota and circadian rhythm in the cardiovascular protective effects of polyphenols by Man, Andy W.C., Xia, Ning, Daiber, Andreas, Li, Huige

“…Polyphenols are secondary metabolites of plants that have been widely studied for their health benefits as antioxidants. In the last decade, several clinical…”
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Involvement of Gut Microbiota, Microbial Metabolites and Interaction with Polyphenol in Host Immunometabolism by Man, Andy W C, Zhou, Yawen, Xia, Ning, Li, Huige

“…Immunological and metabolic processes are inextricably linked and important for maintaining tissue and organismal health. Manipulation of cellular metabolism…”
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Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells by Guo, Yumeng, Xu, Cheng, Man, Andy W C, Bai, Bo, Luo, Cuiting, Huang, Yu, Xu, Aimin, Vanhoutte, Paul M, Wang, Yu

“…Abstract Aims Aged arteries are characterized by attenuated vasodilator and enhanced vasoconstrictor responses, which contribute to the development of diseases…”
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Endothelial Nitric Oxide Synthase in the Perivascular Adipose Tissue by Man, Andy W. C., Zhou, Yawen, Xia, Ning, Li, Huige

“…Perivascular adipose tissue (PVAT) is a special type of ectopic fat depot that adheres to most vasculatures. PVAT has been shown to exert anticontractile…”
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Circadian Rhythm in Adipose Tissue: Novel Antioxidant Target for Metabolic and Cardiovascular Diseases by Man, Andy W C, Xia, Ning, Li, Huige

“…Obesity is a major risk factor for most metabolic and cardiovascular disorders. Adipose tissue is an important endocrine organ that modulates metabolic and…”
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Resveratrol and the Interaction between Gut Microbiota and Arterial Remodelling by Man, Andy W C, Li, Huige, Xia, Ning

“…Arterial remodelling refers to the alteration in the structure of blood vessel that contributes to the progression of hypertension and other cardiovascular…”
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Perivascular Adipose Tissue as a Target for Antioxidant Therapy for Cardiovascular Complications by Man, Andy W C, Zhou, Yawen, Xia, Ning, Li, Huige

“…Perivascular adipose tissue (PVAT) is the connective tissue surrounding most of the systemic blood vessels. PVAT is now recognized as an important endocrine…”
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Renal Effects of Fetal Reprogramming With Pentaerythritol Tetranitrate in Spontaneously Hypertensive Rats by Man, Andy W C, Chen, Min, Wu, Zhixiong, Reifenberg, Gisela, Daiber, Andreas, Münzel, Thomas, Xia, Ning, Li, Huige

“…Current antihypertensive therapies cannot cure hypertension and a life-long medication is necessary. Maternal treatment may represent a promising strategy for…”
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Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin by Man, Andy W C, Zhou, Yawen, Reifenberg, Gisela, Camp, Alica, Münzel, Thomas, Daiber, Andreas, Xia, Ning, Li, Huige

“…Obesity is an epidemic that is a critical contributor to hypertension and other cardiovascular diseases. Current paradigms suggest that endothelial nitric…”
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l‐Citrulline ameliorates pathophysiology in a rat model of superimposed preeclampsia by Man, Andy W. C., Zhou, Yawen, Lam, Uyen D. P., Reifenberg, Gisela, Werner, Anke, Habermeier, Alice, Closs, Ellen I., Daiber, Andreas, Münzel, Thomas, Xia, Ning, Li, Huige

“…Background and Purpose Preeclampsia, characterized by hypertension, proteinuria and restriction of fetal growth, is one of the leading causes of maternal and…”
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Fetal programming effects of pentaerythritol tetranitrate in a rat model of superimposed preeclampsia by Man, Andy W. C., Chen, Min, Zhou, Yawen, Wu, Zhixiong, Reifenberg, Gisela, Daiber, Andreas, Münzel, Thomas, Xia, Ning, Li, Huige

“…Preeclampsia is a common medical condition during pregnancy and a major cause of maternal and prenatal mortality. The present study was conducted to…”
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Cloning and Characterization of Sirtuin3 (SIRT3) by Man, Andy W C, Bai, Bo, Wang, Yu

“…Mitochondria play a pivotal role in maintaining cellular homeostasis and regulating longevity. SIRT3 is a mitochondrial sirtuin mediating the deacetylation of…”
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Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues by Konja, Daniels, Luo, Cuiting, Sun, Wai Yan, Yang, Kangmin, Man, Andy W C, Xu, Aimin, Vanhoutte, Paul M, Wang, Yu

“…Altered vascular tone responsiveness to pathophysiological stimuli contributes to the development of a wide range of cardiovascular and metabolic diseases…”
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Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1 by Bai, Bo, Man, Andy W C, Yang, Kangmin, Guo, Yumeng, Xu, Cheng, Tse, Hung-Fat, Han, Weiping, Bloksgaard, Maria, De Mey, Jo G R, Vanhoutte, Paul M, Xu, Aimin, Wang, Yu

“…Aims-SIRT1 exerts potent activity against cellular senescence and vascular ageing. By decreasing LKB1 protein levels, it promotes the survival and regeneration…”
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Measuring non‐polyaminated lipocalin‐2 for cardiometabolic risk assessment by Yang, Kangmin, Deng, Han‐Bing, Man, Andy W.C., Song, Erfei, Zhang, Jialiang, Luo, Cuiting, Cheung, Bernard M.Y., Yuen, Kwok‐Yung, Jensen, Pia Søndergaard, Irmukhamedov, Akhmadjon, Elie, Atlanta G.I.M., Vanhoutte, Paul M., Xu, Aimin, De Mey, Jo G.R., Wang, Yu

“…Aims Lipocalin‐2 is a pro‐inflammatory molecule characterized by a highly diversified pattern of expression and structure–functional relationships. In vivo,…”
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