Search Results - "Mamo, John C. L."

Synthesis of human amyloid restricted to liver results in an Alzheimer disease–like neurodegenerative phenotype by Lam, Virginie, Takechi, Ryusuke, Hackett, Mark J, Francis, Roslyn, Bynevelt, Michael, Celliers, Liesl M, Nesbit, Michael, Mamsa, Somayra, Arfuso, Frank, Das, Sukanya, Koentgen, Frank, Hagan, Maree, Codd, Lincoln, Richardson, Kirsty, O'Mara, Brenton, Scharli, Rainer K, Morandeau, Laurence, Gauntlett, Jonathan, Leatherday, Christopher, Boucek, Jan, Mamo, John C. L

“…Several lines of study suggest that peripheral metabolism of amyloid beta (Aß) is associated with risk for Alzheimer disease (AD). In blood, greater than 90%…”
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Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid by Majimbi, Maimuna, Brook, Emily, Galettis, Peter, Eden, Edward, Al-Salami, Hani, Mooranian, Armin, Al-Sallami, Hesham, Lam, Virginie, Mamo, John C L, Takechi, Ryusuke

“…Cannabidiol (CBD) confers therapeutic effects in some neurological disorders via modulation of inflammatory, oxidative and cell-signalling pathways. However,…”
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Blood–brain barrier disruption and ventricular enlargement are the earliest neuropathological changes in rats with repeated sub-concussive impacts over 2 weeks by Hiles-Murison, Bailey, Lavender, Andrew P., Hackett, Mark J., Armstrong, Joshua J., Nesbit, Michael, Rawlings, Samuel, McGonigle, Terrence, Warnock, Andrew, Lam, Virginie, Mamo, John C. L., Fitzgerald, Melinda, Takechi, Ryu

“…Repeated sub-concussive impact (e.g . soccer ball heading), a significantly lighter form of mild traumatic brain injury, is increasingly suggested to…”
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The differential effects of fatty acids on enterocytic abundance of amyloid-beta by Galloway, Susan, Takechi, Ryusuke, Nesbit, Michael, Pallebage-Gamarallage, Menuka M, Lam, Virginie, Mamo, John C L

“…Consumption of a Western-styled diet enriched in saturated fatty acids (SFA) relative to polyunsaturated fatty acids is positively associated with risk for…”
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The vitamin D, ionised calcium and parathyroid hormone axis of cerebral capillary function: therapeutic considerations for vascular-based neurodegenerative disorders by Lam, Virginie, Takechi, Ryusuke, Pallabage-Gamarallage, Menuka, Giles, Corey, Mamo, John C L

“…Blood-brain barrier dysfunction characterised by brain parenchymal extravasation of plasma proteins may contribute to risk of neurodegenerative disorders,…”
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Biospectroscopic Imaging Provides Evidence of Hippocampal Zn Deficiency and Decreased Lipid Unsaturation in an Accelerated Aging Mouse Model by Fimognari, Nicholas, Hollings, Ashley, Lam, Virginie, Tidy, Rebecca J, Kewish, Cameron M, Albrecht, Matthew A, Takechi, Ryu, Mamo, John C. L, Hackett, Mark J

“…Western society is facing a health epidemic due to the increasing incidence of dementia in aging populations, and there are still few effective diagnostic…”
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Serum 25-hydroxyvitamin D is associated with reduced verbal episodic memory in healthy, middle-aged and older adults by Lam, Virginie, Albrecht, Matthew A., Takechi, Ryusuke, Prasopsang, Prachya, Lee, Ya Ping, Foster, Jonathan K., Mamo, John C. L.

“…Background There is increasing evidence supporting an association of higher serum vitamin D concentration with better cognitive performance in older…”
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Blood-Brain Barrier Dysfunction Precedes Cognitive Decline and Neurodegeneration in Diabetic Insulin Resistant Mouse Model: An Implication for Causal Link by Takechi, Ryusuke, Lam, Virginie, Brook, Emily, Giles, Corey, Fimognari, Nicholas, Mooranian, Armin, Al-Salami, Hani, Coulson, Stephanie H, Nesbit, Michael, Mamo, John C L

“…Diabetic insulin resistance and pro-diabetic diet are reported to increase dementia risk through unknown mechanisms. Emerging evidence suggests that the…”
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Peripheral Administration of the Kv1.3-Blocking Peptide HsTX1[R14A] Improves Cognitive Performance in Senescence Accelerated SAMP8 Mice by Pan, Yijun, Kagawa, Yoshiteru, Sun, Jiaqi, Lucas, Deanna S. Deveson, Takechi, Ryusuke, Mamo, John C.L., Wai, Dorothy C.C., Norton, Raymond S., Jin, Liang, Nicolazzo, Joseph A.

“…Increased expression of the voltage-gated potassium channel Kv1.3 in activated microglia, and the subsequent release of pro-inflammatory mediators, are closely…”
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Colocalisation of plasma derived apo B lipoproteins with cerebral proteoglycans in a transgenic-amyloid model of Alzheimer's disease by Lam, Virginie, Takechi, Ryusuke, Pallebage-Gamarallage, Menuka Madhavi Sompala, Galloway, Susan, Mamo, John C.L.

“…► Significant amyloid-beta is associated with apolipoprotein (apo) B lipoproteins. ► Some proteoglycans are associated with apo B lipoproteins in amyloid…”
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Exposure to biodiesel exhaust is less harmful than exposure to mineral diesel exhaust on blood-brain barrier integrity in a murine model by Nesbit, Michael, Ko, Colleen Kah Ling, Mamo, John C L, Lam, Virginie, Landwehr, Katherine R, Larcombe, Alexander N, Takechi, Ryu

“…Emerging data suggest that air pollution is a persistent source of neuroinflammation, reactive oxygen species (ROS), and neuropathology that contributes to…”
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Using optical coherence tomography and optical coherence tomography angiography to delineate neurovascular homeostasis in migraine: a review by Chaliha, Devahuti R, Vaccarezza, Mauro, Charng, Jason, Chen, Fred K, Lim, Amy, Drummond, Peter, Takechi, Ryusuke, Lam, Virginie, Dhaliwal, Satvinder S, Mamo, John C L

“…Migraine is one of the world's most debilitating disorders, and it has recently been shown that changes in the retina can be a potential biomarker for the…”
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Tailored, iterative, printed dietary feedback is as effective as group education in improving dietary behaviours: results from a randomised control trial in middle-aged adults with cardiovascular risk factors by Wright, Janine L, Sherriff, Jillian L, Dhaliwal, Satvinder S, Mamo, John C L

“…Tailored nutrition interventions have been shown to be more effective than non-tailored materials in changing dietary behaviours, particularly fat intake and…”
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Chronic Intake of Energy Drinks and Their Sugar Free Substitution Similarly Promotes Metabolic Syndrome by Graneri, Liam T, Mamo, John C L, D'Alonzo, Zachary, Lam, Virginie, Takechi, Ryusuke

“…Energy drinks containing significant quantities of caffeine, taurine and sugar are increasingly consumed, particularly by adolescents and young adults. The…”
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Hypertriglyceridemia and Alzheimer Disease: Opening the Mind to New Therapeutic Opportunities by Watts, Gerald F, Mamo, John C.L.

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記憶障害とメタローム解析：脳神経系における金属イオン欠乏は認知症の一因となるか by 武智, 隆祐, 奥山, 聡

“…「1. はじめに」 認知症には適切な治療法がないことから国際的な健康危機状態にあり, 世界的な経済的コストは2030年までに2兆ドル(USD)に達すると予測されて, これに加えてQOLの損失は計り知れないものがある. 認知症共通の病理学的特徴として, 金属イオンの蓄積が挙げられ, 具体的には,…”
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Chronic high fat feeding paradoxically attenuates cerebral capillary dysfunction and neurovascular inflammation in Senescence-Accelerated-Murine-Prone Strain 8 mice by Lam, Virginie, Stephenson, Andrea, Nesbit, Michael, Mamsa, Somayra, Hackett, Mark, Takechi, Ryusuke, Mamo, John C. L.

“…Background: A body of epidemiological, clinical and preclinical studies suggest increased risk for cerebro- and cardio-vascular disease associated with dietary…”
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Is type 2 diabetes associated dementia a microvascular early-Alzheimer's phenotype induced by aberrations in the peripheral metabolism of lipoprotein-amyloid? by Takechi, Ryusuke, Sharif, Arazu, Brook, Emily, Majimbi, Maimuna, Chan, Dick C, Lam, Virginie, Watts, Gerald F, Mamo, John C L

“…There is increasing evidence of a positive association of type 2 diabetes with Alzheimer's disease (AD), the most prevalent form of dementia. Suggested…”
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Plasma Amyloid-β Homeostasis Is Associated with Body Mass Index and Weight Loss in People with Overweight and Obesity by Brook, Emily S, D'Alonzo, Zachary J, Lam, Virginie, Chan, Dick C, Dhaliwal, Satvinder S, Watts, Geraldb F, Mamo, John C L, Takechi, Ryusuke

“…Obesity is linked to a higher incidence of Alzheimer's disease (AD). Studies show that plasma amyloid-β (Aβ) dyshomeostasis, particularly low 42/40 ratio…”
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The Effects of Chronic Consumption of Lipid-Rich and Delipidated Bovine Dairy Milk on Brown Adipose Tissue Volume in Wild-Type Mice by D'Alonzo, Zachary J, Mamo, John C L, Graneri, Liam T, Takechi, Ryusuke, Lam, Virginie

“…Brown adipose tissue (BAT) activation is associated with increased energy expenditure by inducing non-shivering thermogenesis. The ingestion of a milk fat…”
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