Search Results - "Mammoliti, Serafina"
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The fading guardian: clinical relevance of TP53 null mutation in high-grade serous ovarian cancers
Published in Frontiers in immunology (23-08-2023)“…Background we evaluated the concordance between immunohistochemical p53 staining and TP53 mutations in a series of HGSOC. Moreover, we searched for prognostic…”
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Neoadjuvant chemotherapy and vaginal radical trachelectomy for fertility-sparing treatment in women affected by cervical cancer (FIGO stage IB–IIA1)
Published in Gynecologic oncology (01-09-2011)“…Abstract Objectives The aim of the present report is to support the feasibility and the safety of a new fertility-sparing treatment in young women affected by…”
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3
Neoadjuvant Chemotherapy Followed by Radical Surgery versus Concurrent Chemo-Radiotherapy in the Treatment of Locally Advanced Cervical Cancer: A Multicenter Retrospective Analysis
Published in Journal of investigative surgery (01-02-2022)“…This study aims to evaluate oncological outcomes in women affected by locally advanced cervical cancer (LACC) treated by neoadjuvant chemotherapy before…”
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4
Management of metastatic endometrial cancer: physicians' choices beyond the first line after approval of checkpoint inhibitors
Published in Frontiers in oncology (14-09-2023)“…Endometrial cancer (EC) represents 3.4% of all newly diagnosed cancer cases and is responsible for 2.1% of all cancer-related deaths. Approximately 10%-15% of…”
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Corrigendum: Management of metastatic endometrial cancer: physicians' choices beyond the first line after approval of checkpoint inhibitors
Published in Frontiers in oncology (22-01-2024)“…[This corrects the article DOI: 10.3389/fonc.2023.1247291.]…”
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Management of Metastatic Endometrial Cancer: Physicians' Choices Beyond the First Line. A MITO Survey
Published in Frontiers in oncology (27-05-2022)“…Endometrial cancer (EC) therapeutic and diagnostic approaches have been changed by the development of a new prognostic molecular classification, the…”
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Histopathological and Immunohistochemical Prognostic Factors in High-Grade Non-Endometrioid Carcinomas of the Endometrium (HG-NECs): Is It Possible to Identify Subgroups at Increased Risk?
Published in Diagnostics (Basel) (26-06-2023)“…Endometrial cancer is an emerging disease with an increase in prevalence of aggressive histotypes in recent years. In the present study, potential…”
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Peritoneal carcinomatosis from ovarian paraganglioma: Report of a rare case and systematic review of the literature
Published in The journal of obstetrics and gynaecology research (01-09-2018)“…Paraganglioma is one of the rarest neoplasms involving the ovary, with only 10 previous reports. We present a case of peritoneal carcinomatosis from primary…”
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Complete response in a patient with gynecological hidradenocarcinoma treated with exclusive external beam radiotherapy and brachytherapy: a case report
Published in Journal of contemporary brachytherapy (01-01-2017)“…Hidradenocarcinoma (HC) is a very rare disease. This case report illustrates a successful treatment of a 60-year-old woman with vulvo-vaginal localization of…”
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Upfront FOLFOXIRI plus bevacizumab and reintroduction after progression versus mFOLFOX6 plus bevacizumab followed by FOLFIRI plus bevacizumab in the treatment of patients with metastatic colorectal cancer (TRIBE2): a multicentre, open-label, phase 3, randomised, controlled trial
Published in The lancet oncology (01-04-2020)“…The triplet FOLFOXIRI (fluorouracil, leucovorin, oxaliplatin, and irinotecan) plus bevacizumab showed improved outcomes for patients with metastatic colorectal…”
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Carboplatin-based doublet plus bevacizumab beyond progression versus carboplatin-based doublet alone in patients with platinum-sensitive ovarian cancer: a randomised, phase 3 trial
Published in The lancet oncology (01-02-2021)“…Bevacizumab is approved in combination with chemotherapy for the treatment of ovarian cancer, either in first-line therapy or for patients with recurrent…”
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12
A phase II study of aflibercept in patients with advanced epithelial ovarian cancer and symptomatic malignant ascites
Published in Gynecologic oncology (01-04-2012)“…Abstract Objective The recombinant fusion protein, aflibercept binds and neutralizes vascular endothelial growth factor (VEGF) A, B and placental growth factor…”
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Single-Agent Trabectedin Versus Physician's Choice Chemotherapy in Patients With Recurrent Ovarian Cancer With BRCA -Mutated and/or BRCAness Phenotype: A Randomized Phase III Trial
Published in Journal of clinical oncology (01-05-2024)“…Literature evidence suggests that trabectedin monotherapy is effective in patients with recurrent ovarian cancer (OC) presenting mutation and/or BRCAness…”
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Real-life efficacy and safety of cemiplimab in advanced cervical cancer from a nominal use program in Italy: The MITO 44 study
Published in European journal of cancer (1990) (01-05-2024)“…cemiplimab is an immunoglobulin G4 monoclonal antibody targeting the programmed cell death-1 receptor. A nominal use program is available in Italy in advanced…”
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Consensus statements and treatment algorithm to guide clinicians in the selection of maintenance therapy for patients with newly diagnosed, advanced ovarian carcinoma: Results of a Delphi study
Published in Gynecologic oncology (01-08-2023)“…•Several treatment options for ovarian carcinoma are available beyond chemotherapy (83).•Maintenance therapy with bevacizumab and/or PARPi can prolong survival…”
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Reliability of patient-reported toxicities during adjuvant chemotherapy
Published in European journal of cancer (1990) (01-03-2023)“…Patient-reported outcomes (PROs) are validated tools to assess the impact of efficacy and toxicities of cancer treatments on patients’ health status. Because…”
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Brain metastases in patients with EOC: Clinico-pathological and prognostic factors. A multicentric retrospective analysis from the MITO group (MITO 19)
Published in Gynecologic oncology (01-12-2016)“…Abstract Background Brain metastases (BM) from epithelial ovarian cancer (EOC) are considered a rare and unfavourable event. There is no consensus regarding…”
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Randomized phase III trial on trabectedin (ET-743) single agent versus clinician’s choice chemotherapy in recurrent ovarian, primary peritoneal, or fallopian tube cancers of BRCA-mutated or BRCAness phenotype patients (MITO23)
Published in Journal of clinical oncology (10-06-2022)“…LBA5504 Background: Trabectedin demonstrated antitumor activity when administered as single agent in relapsed platinum sensitive ovarian cancer (OC), with an…”
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Prescribing pattern of anticoagulants in patients with cancer associated thrombosis: Results of a survey among MITO group and AIOM society
Published in Tumori (01-10-2023)“…Introduction: Low molecular weight heparin (LMWH) has been the backbone of the treatment of cancer associated thrombosis (CAT). Direct-acting oral…”
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The prognostic value of FIGO staging defined by combining MRI and [ 18 F]FDG PET/CT in patients with locally advanced cervical cancer
Published in Current problems in cancer (01-12-2023)“…The last version of the FIGO classification recommended imaging tools to complete the clinical assessment of patients with cervical cancer. However, the…”
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