Search Results - "Mamiko Kai"

Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors-lessons from available evidence and insights into COVID-19 by Kai, Hisashi, Kai, Mamiko

“…The rapid spread of a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to an ongoing pandemic of coronavirus disease…”
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Overexpression of angiotensin-converting enzyme 2 by renin-angiotensin system inhibitors. Truth or myth? A systematic review of animal studies by Kai, Hisashi, Kai, Mamiko, Niiyama, Hiroshi, Okina, Norihito, Sasaki, Motoki, Maeda, Takanobu, Katoh, Atsushi

“…Angiotensin-converting enzyme 2 (ACE2) protects against organ damage in hypertension and cardiovascular diseases by counter regulating the renin-angiotensin…”
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More Attention Should Be Paid to Abnormalities of Circadian Blood Pressure Rhythm in Heart Failure Patients by Kai, Mamiko, Kai, Hisashi

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Enhanced cardiac inflammation and fibrosis in ovariectomized hypertensive rats: a possible mechanism of diastolic dysfunction in postmenopausal women by Mori, Takahiro, Kai, Hisashi, Kajimoto, Hidemi, Koga, Mitsuhisa, Kudo, Hiroshi, Takayama, Narimasa, Yasuoka, Suguru, Anegawa, Takahiro, Kai, Mamiko, Imaizumi, Tsutomu

“…Diastolic dysfunction is more prevalent in individuals with hypertension, particularly postmenopausal women; however, the pathogenesis of diastolic dysfunction…”
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Mutant MCP-1 therapy inhibits tumor angiogenesis and growth of malignant melanoma in mice by Koga, Mitsuhisa, Kai, Hisashi, Egami, Kimiyasu, Murohara, Toyoaki, Ikeda, Ayami, Yasuoka, Suguru, Egashira, Kensuke, Matsuishi, Toyojiro, Kai, Mamiko, Kataoka, Yasufumi, Kuwano, Michihiko, Imaizumi, Tsutomu

“…We investigated whether blocking of monocyte chemoattractant-1 (MCP-1) function would inhibit recruitment of tumor-associated macrophages (TAMs) and prevent…”
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S-39-2: EFFECTS OF RAS INHIBITORS ON TISSUE ACE2 EXPRESSION IN ANIMAL MODELS by Kai, Hisashi, Kai, Mamiko

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Postnatal Blocking of Interferon-γ Function Prevented Atherosclerotic Plaque Formation in Apolipoprotein E-Knockout Mice by Koga, Mitsuhisa, Kai, Hisashi, Yasukawa, Hideo, Kato, Seiya, Yamamoto, Tomoka, Kawai, Yumiko, Kusaba, Ken, Seki, Yukihiko, Kai, Mamiko, Egashira, Kensuke, Kataoka, Yasufumi, Imaizumi, Tsutomu

“…It is unknown whether interferon-gamma has a positive or negative impact on atherosclerotic plaque formation. Thus, we examined the effects of postnatal…”
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Nitric oxide mediates cyclosporine-induced impairment of the blood–brain barrier in cocultures of mouse brain endothelial cells and rat astrocytes by Dohgu, Shinya, Yamauchi, Atsushi, Nakagawa, Shinsuke, Takata, Fuyuko, Kai, Mamiko, Egawa, Takashi, Naito, Mikihiko, Tsuruo, Takashi, Sawada, Yasufumi, Niwa, Masami, Kataoka, Yasufumi

“…The present study was designed to clarify the involvement of nitric oxide (NO) signaling in the adverse effect of cyclosporine on the blood–brain barrier…”
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Permeation-Enhancing Effect of Aloe-emodin Anthrone on Water-Soluble and Poorly Permeable Compounds in Rat Colonic Mucosa by Kai, Mamiko, Hayashi, Kazutaka, Kaida, Ippei, Aki, Hatsumi, Yamamoto, Magobei

“…The aims of this study were to examine the enhancing effects of aloe-emodin anthrone (AEA) on the colonic membrane permeability of water-soluble and poorly…”
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Soybean Isoflavones Eliminate Nifedipine-Induced Flushing of Tail Skin in Ovariectomized Mice by Kai, Mamiko, Yamauchi, Atsushi, Tominaga, Koji, Koga, Ayako, Kai, Hisashi, Kataoka, Yasufumi

“…Hot flushes are one of the most frequent symptoms in menopausal women. We investigated effect of soybean isoflavones (Soyaflavone HG) on nifedipine-induced…”
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PS-C28-1: EARLY DETECTION OF DEMENTIA AT COMMUNITY PHARMACIES USING SIMPLE TOUCH PANEL SCREENING CHECK by Kai, Mamiko, Tominaga, Koji, Morita, Kazutoshi, Soda, Yoshio, Sejima, Ei, Dendo, Hitomi, Yamaguchi, Ryosuke, Takada, Makiko, Akura, Hiroshi, Ono, Kazuhiko, Hayashi, Toshinobu, Iida, Hitoshi, Ogomori, Koji, Kawasaski, Hiroaki, Egawa, Takashi

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Assessment of inter-rater agreement between physicians and their patients regarding medication adherence in a clinical questionnaire study by Otsu, Yuki, Kai, Mamiko, Suematsu, Yasunori, Kiyomi, Fumiaki, Saku, Keijiro, Kamimura, Hidetoshi, Miura, Shin-ichiro

“…While it is important to treat lifestyle-related diseases for the primary and secondary prevention of cardiovascular diseases, medication adherence is still…”
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Transforming growth factor-β function blocking prevents myocardial fibrosis and diastolic dysfunction in pressure-overloaded rats by KUWAHARA, Fumitaka, KAI, Hisashi, TOKUDA, Keisuke, KAI, Mamiko, TAKESHITA, Akira, EGASHIRA, Kensuke, IMAIZUMI, Tsutomu

“…Excessive myocardial fibrosis impairs cardiac function in hypertensive hearts. Roles of transforming growth factor (TGF)-beta in myocardial remodeling and…”
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Ovariectomy aggravates sildenafil-induced flushing of tail skin in mice by Ayako Koga, Atsushi Yamauchi, Munehiko Ikeda, Yoshio Sohda, Kohji Tominaga, Mamiko Kai, Takashi Egawa, Yasufumi Kataoka

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Interferon-γ-A New Target for prevention of Atheroscleotis by Mitsuhisa Koga, Hisashi Kai, Mamiko Kai, Tomoka Yamamoto, Tsutomu Imaizumi, Yasufumi Kataoka

“…The aim of this study was to determine whether the development of atheroscleotic lesions can be prevented by interferon-y (IFN-γ) functional blocking in apoE…”
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Inhibition of Progression and Stabilization of Plaques by Postnatal Interferon-γ Function Blocking in ApoE-Knockout Mice by Koga, Mitsuhisa, Kai, Hisashi, Yasukawa, Hideo, Yamamoto, Tomoka, Kawai, Yumiko, Kato, Seiya, Kusaba, Ken, Kai, Mamiko, Egashira, Kensuke, Kataoka, Yasufumi, Imaizumi, Tsutomu

“…A role of interferon-γ is suggested in early development of atherosclerosis. However, the role of interferon-γ in progression and destabilization of advanced…”
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Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes by Kai, Hisashi, Ikeda, Hisao, Yasukawa, Hideo, Kai, Mamiko, Seki, Yukihiko, Kuwahara, Fumitaka, Ueno, Takafumi, Sugi, Kenzo, Imaizumi, Tsutomu

“…Objectives. This study was sought to investigate whether peripheral blood levels of matrix metalloproteases (MMPs) are affected in patients with acute coronary…”
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Detection of 3,6-dinitrobenzo[a]pyrene in airborne particulates by Sera, N, Kai, M, Horikawa, K, Fukuhara, K, Miyata, N, Tokiwa, H

“…3,6-Dinitrobenzo[a]pyrene, a new mutagen, was detected in airborne particulates collected in Santiago (Chile). The quantity of the compound in the airborne…”
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Structure-Activity Relationship of a New Series of Tricyclic Monoamine Oxidase Inhibitors of Pentanthrene Type by KAI, MAMIKO, NODA, ATSUKO, NODA, HIROSHI, GOTO, SHIGERU

“…This study was undertaken to evaluate the relationship between the structure and monoamine oxidase (MAO) inhibitory activity of a new series of tricyclic…”
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Inhibition of Progression and Stabilization of Plaques by Postnatal Interferon-g Function Blocking in ApoE-Knockout Mice by Koga, Mitsuhisa, Kai, Hisashi, Yasukawa, Hideo, Yamamoto, Tomoka, Kawai, Yumiko, Kato, Seiya, Kusaba, Ken, Kai, Mamiko, Egashira, Kensuke, Kataoka, Yasufumi, Imaizumi, Tsutomu

“…A role of interferon-g is suggested in early development of atherosclerosis. However, the role of interferon-g in progression and destabilization of advanced…”
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