Search Results - "Mamidala, Estari"

Rilpivirine inhibits SARS-CoV-2 protein targets: A potential multi-target drug by Ameen, Fuad, Mamidala, Estari, Davella, Rakesh, Vallala, Shravan

“…COVID-19 disease caused by SARS-CoV-2 is lacking efficient medication although certain medications are used to relief its symptoms. We tested an FDA-approved…”
Get full text

Nephroprotective Effects of Mycophenolate Mofetil and Glibenclamide on Streptozotocin-induced Diabetic Renal Injury in Rats: An Experimental Study by Boju, Sangeetha Lakshmi, Kotha, Peddanna, Nasreen, A, Gurrapu, Swapna, Mamidala, Estari, Ram, R, Chintamaneni, Srilatha, Chippada, Appa Rao, Vishnubhotla, Siva Kumar

“…Diabetic renal injury is a microvascular complication associated with inflammation and oxidative stress, culminating in renal dysfunction. Conventionally, it…”
Get full text

Synthesis, molecular docking simulation, and biological evaluation studies of novel amide and ether conjugates of 2,3‐diaryl‐1,3‐thiazolidin‐4‐ones by Daipule, Komal, Goud, Nerella Sridhar, Sethi, Aaftaab, Gurrapu, Swapna, Mamidala, Estari, Alvala, Mallika

“…With an aim to develop potent lead molecules as a novel class of reverse transcriptase (RT) inhibitors, we have synthesized amide and ether conjugates of…”
Get full text

Plant-based triboelectric nanogenerator for biomechanical energy harvesting by Babu, Anjaly, Rakesh, D., Supraja, P., Mishra, Siju, Kumar, K. Uday, Kumar, R. Rakesh, Haranath, D., Mamidala, Estari, Nagapuri, Raju

“…As people became more aware of environmental issues, several designs of triboelectric energy harvesters based on biocompatible and eco-friendly natural…”
Get full text

Synthesis, anticancer and antibacterial evaluation of novel (isopropylidene) uridine-[1,2,3]triazole hybrids by Thatipamula, Ranjith kumar, Narsimha, Sirassu, Battula, Kumaraswamy, Rajendra Chary, V., Mamidala, Estari, Vasudeva Reddy, Nagavelli

“…A series of novel (isopropylidene) uridine-[1,2,3]triazole hybrids (3a–3n) were efficiently synthesized via the copper-catalyzed azide–alkyne cycloaddition…”
Get full text

Effects of D-Limonene on aldose reductase and protein glycation in diabetic rats by Praveen Kumar, Munipally, Poornima, Mamidala, Estari, Al-Ghanim, Khalid, Al-Misned, Fahad, Ahmed, Zubair, Mahboob, Shahid

“…Diabetes mellitus and hyperglycemia can lead to other health complications. The pathogenesis of diabetes mellitus can affect numerous tissues in the eye…”
Get full text

In vitro anti-HIV activity of crude extracts from Tinospora cordifolia by Estari, Mamidala, Venkanna, Lunavath, Reddy, Annem Srinivas

“…Doc number: P10…”
Get full text

Identification of steroidal cardenolides from Calotropis procera as novel HIV-1 PR inhibitors: A molecular docking & molecular dynamics simulation study by Swapna, Kandagatla, Srujana, M, Mamidala, Estari

“…Background & objectives Despite advancements in antiretroviral therapy, drug-resistant strains of HIV (human immunodeficiency virus) remain a global health…”
Get full text

Phenolic compounds as promising drug candidates against COVID-19 - an integrated molecular docking and dynamics simulation study by Davella, Rakesh, Gurrapu, Swapna, Mamidala, Estari

“…Piper was used to cure certain human afflictions. It has various biological processes in literary works. Our work aims to identify and to explain the molecular…”
Get full text

In silico toxicity prediction, molecular docking studies and in vitro validation of antibacterial potential of alkaloids from Eclipta alba in designing of novel antimicrobial therapeutic strategies by Ameen, Fuad, Orfali, Raha, Mamidala, Estari, Davella, Rakesh

“…The rapid emergence of various drug resistance and unfavourable aliphatic medication side effects endangers people's health. Phytocompounds with antibacterial…”
Get full text

A novel library of -arylketones as potential inhibitors of α-glucosidase: Their design, synthesis, in vitro and in vivo studies by Luthra, Tania, Agarwal, Rahul, Estari, Mamidala, Adepally, Uma, Sen, Subhabrata

“…α-glucosidase is an essential enzyme located at the brush border of intestines. It is an important therapeutic target for type II diabetes. Herein we have…”
Get full text

Antidiabetic effect of flavonoid from Rumex vesicarius on alloxan induced diabetes in Male Albino Wistar rats and its validation through in silico molecular docking and dynamic simulation studies by Al-Masri, Abeer A., Ameen, Fuad, Davella, Rakesh, Mamidala, Estari

“…The leaves of Rumex vescarius L. are used locally to treat diabetes, a chronic illness. A flavonoid called Luteolin from R. vesicarius was chosen to explore…”
Get full text

HIV-1 reverse transcriptase inhibitory activity of Aerva lanata plant extracts by Gujjeti, Rajendra Prasad, Namthabad, Sainath, Mamidala, Estari

Get full text

Evaluation of the andrographolides role and its indoleamine 2,3-dioxygenase inhibitory potential and attendant molecular mechanism against STZ-induced diabetic rats by Kumar, Munipally Praveen, Mamidala, Estari, Al-Ghanim, Khalid A., Al-Misned, F., Mahboob, Shahid

“…The study is to scrutinize andrographolides with Indoleamine 2,3-dioxygenase (IDO) inhibitory potential, its molecular mechanism against streptozotocin (STZ)…”
Get full text

In silico prediction of mozenavir as a potential drug for SARS-CoV-2 infection via binding multiple drug targets by Mamidala, Estari, Davella, Rakesh, Praveen Kumar, Munipally, Swamy, Satyanarayana, Abhiav, Mruthinti, Ali Kaimkhani, Zahid, Al-Ghanim, K.A., Mahboob, Shahid

“…Since the epidemic began in November 2019, no viable medicine against SARS-CoV-2 has been discovered. The typical medication discovery strategy requires…”
Get full text

Molecular interactions between β-lactoglobulin protein and phytocannabinoids: a molecular docking and dynamics simulation study by Atanu, Francis O., Mamidala, Estari, Nwonuma, Charles O., Alejolowo, Omookolade O.

“…Cannabinoids are phytochemicals with important pharmacological benefits. However, cannabinoid-based therapies suffer from poor bioavailability due to their…”
Get full text

In silico identification of clinically approved medicines against the main protease of SARS-CoV-2, causative agent of covid-19 by Mamidala, Estari, Davella, Rakesh, Gurrapu, Swapna, Shivakrishna, Pujala

“…The COVID-19 pandemic triggered by SARS-CoV-2 is a worldwide health disaster. Main protease is an attractive drug target among coronaviruses, due to its vital…”
Get full text