Search Results - "Mami, Iadh"
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Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress
Published in Nature communications (07-12-2018)“…Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. Here, we identify a hepatocellular carcinoma (HCC) subgroup exhibiting…”
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2
tRNA fragmentation and protein translation dynamics in the course of kidney injury
Published in RNA biology (02-09-2018)“…Cells under stressful microenvironmental conditions initiate integrated molecular circuitries that aim at reducing general protein translation rates while…”
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High prevalence of and potential mechanisms for chronic kidney disease in patients with acute intermittent porphyria
Published in Kidney international (01-08-2015)“…Acute intermittent porphyria (AIP) is a genetic disorder of the synthesis of heme caused by a deficiency in hydroxymethylbilane synthase (HMBS), leading to the…”
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Tryptophan depletion and the kinase GCN2 mediate IFN-γ-induced autophagy
Published in The Journal of immunology (1950) (15-09-2012)“…IFN-γ is a master regulator of the immune responses that occur in the transplanted kidney, acting both on the immune system and on the graft itself. The…”
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Urinary Angiogenin Reflects the Magnitude of Kidney Injury at the Infrahistologic Level
Published in Journal of the American Society of Nephrology (01-02-2017)“…The ribonuclease angiogenin is a component of the mammalian stress response that is secreted by renal epithelial cells on activation of the inositol-requiring…”
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A Novel Extrinsic Pathway for the Unfolded Protein Response in the Kidney
Published in Journal of the American Society of Nephrology (01-09-2016)“…The ribonuclease angiogenin is a component of the mammalian stress response, and functions in both cell-autonomous and non-cell-autonomous ways to promote…”
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Angiogenin Mediates Cell-Autonomous Translational Control under Endoplasmic Reticulum Stress and Attenuates Kidney Injury
Published in Journal of the American Society of Nephrology (01-03-2016)“…Endoplasmic reticulum (ER) stress is involved in the pathophysiology of kidney disease and aging, but the molecular bases underlying the biologic outcomes on…”
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Wild-type AAV Insertions in Hepatocellular Carcinoma Do Not Inform Debate Over Genotoxicity Risk of Vectorized AAV
Published in Molecular therapy (01-04-2016)Get full text
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