Search Results - "Malyutin, Andrey G."
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SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
Published in Nature (London) (24-12-2020)“…The coronavirus disease 2019 (COVID-19) pandemic presents an urgent health crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding…”
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The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function
Published in Nature communications (21-11-2023)“…Polymeric (p) immunoglobulins (Igs) serve broad functions during vertebrate immune responses. Typically, pIgs contain between two and six Ig monomers, each…”
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The structures of secretory and dimeric immunoglobulin A
Published in eLife (27-10-2020)“…Secretory (S) Immunoglobulin (Ig) A is the predominant mucosal antibody, which binds pathogens and commensal microbes. SIgA is a polymeric antibody, typically…”
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The T-cell leukemia related rpl10-R98S mutant traps the 60S export adapter Nmd3 in the ribosomal P site in yeast
Published in PLoS genetics (17-07-2017)“…Mutations in the ribosomal protein Rpl10 (uL16) can be drivers of T-cell acute lymphoblastic leukemia (T-ALL). We previously showed that these T-ALL mutations…”
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Characterization of Reactive Organometallic Species via MicroED
Published in ACS central science (25-09-2019)“…Here we apply microcrystal electron diffraction (MicroED) to the structural determination of transition-metal complexes. We find that the simultaneous use of…”
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Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis
Published in The EMBO journal (03-04-2017)“…During ribosome biogenesis in eukaryotes, nascent subunits are exported to the cytoplasm in a functionally inactive state. 60S subunits are activated through a…”
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Microcrystal Electron Diffraction Elucidates Water-Specific Polymorphism-Induced Emission Enhancement of Bis-arylacylhydrazone
Published in ACS applied materials & interfaces (17-02-2021)“…Aggregation-induced emission (AIE) phenomena have gained intense interest over the last decades because of its importance in solid-state emission. However, the…”
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Budding Pathway in the Templated Assembly of Viruslike Particles
Published in The journal of physical chemistry. B (19-09-2013)“…A new pathway for the assembly of viral capsid protein around inorganic nanoparticle cores was observed by time-course light scattering and cryo-electron…”
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Author Correction: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
Published in Nature (London) (18-04-2024)Get full text
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10
Computational identification of a systemic antibiotic for Gram-negative bacteria
Published in Nature microbiology (01-10-2022)“…Discovery of antibiotics acting against Gram-negative species is uniquely challenging due to their restrictive penetration barrier. BamA, which inserts…”
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Viruslike Nanoparticles with Maghemite Cores Allow for Enhanced MRI Contrast Agents
Published in Chemistry of materials (13-01-2015)“…Here, for the first time, we demonstrate formation of virus-like nanoparticles (VNPs) utilizing gold-coated iron oxide nanoparticles as cores and capsid…”
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Nanoparticles by Decomposition of Long Chain Iron Carboxylates: From Spheres to Stars and Cubes
Published in Langmuir (15-03-2011)“…In this paper, we report the influence of reaction conditions and the chain length on the nanoparticle (NP) size and morphology for thermal decomposition of…”
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Coat Protein-Dependent Behavior of Poly(ethylene glycol) Tails in Iron Oxide Core Virus-like Nanoparticles
Published in ACS applied materials & interfaces (10-06-2015)“…Here we explore the formation of virus-like nanoparticles (VNPs) utilizing 22–24 nm iron oxide nanoparticles (NPs) as cores and proteins derived from viral…”
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Solution study of novel diblock copolymers: Morphology and structural transition
Published in Polymer (Guilford) (13-12-2013)“…The solution behavior and morphology of the nanostructures formed by novel block copolymers based on 1-cetyl[2-(acryloyloxy)ethyl]dimethylammonium bromide…”
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15
Nmd3 is a structural mimic of eIF 5A, and activates the cp GTP ase Lsg1 during 60S ribosome biogenesis
Published in The EMBO journal (03-04-2017)Get full text
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16
Viruslike Nanoparticles with Maghemite Cores Allow for Enhanced MRI Contrast Agents
Published in Chemistry of materials (23-12-2014)“…Here, for the first time, we demonstrate formation of virus-like nanoparticles (VNPs) utilizing gold-coated iron oxide nanoparticles as cores and capsidprotein…”
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17
Characterization of Reactive Organometallic Species via MicroED
Published in ACS central science (06-09-2019)“…Not provided…”
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18
Solution study of novel diblock copolymers: Morphology and structural transition
Published in Polymer (Guilford) (2013)Get full text
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