Search Results - "Malvacio, Ivana"

Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump by Vargiu, Attilio Vittorio, Ramaswamy, Venkata Krishnan, Malvacio, Ivana, Malloci, Giuliano, Kleinekathöfer, Ulrich, Ruggerone, Paolo

“…Efflux pumps of the Resistance-Nodulation-cell Division superfamily confer multi-drug resistance to Gram-negative bacteria. The most-studied polyspecific…”
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DockBench: An Integrated Informatic Platform Bridging the Gap between the Robust Validation of Docking Protocols and Virtual Screening Simulations by Cuzzolin, Alberto, Sturlese, Mattia, Malvacio, Ivana, Ciancetta, Antonella, Moro, Stefano

“…Virtual screening (VS) is a computational methodology that streamlines the drug discovery process by reducing costs and required resources through the in…”
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Synthesis and preliminary structure-activity relationship study of 2-aryl-2H-pyrazolo[4,3-c]quinolin-3-ones as potential checkpoint kinase 1 (Chk1) inhibitors by Malvacio, Ivana, Cuzzolin, Alberto, Sturlese, Mattia, Vera, D. Mariano A., Moyano, E. Laura, Moro, Stefano

“…The serine-threonine checkpoint kinase 1 (Chk1) plays a critical role in the cell cycle arrest in response to DNA damage. In the last decade, Chk1 inhibitors…”
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Computer simulations of the activity of RND efflux pumps by Vargiu, Attilio Vittorio, Ramaswamy, Venkata Krishnan, Malloci, Giuliano, Malvacio, Ivana, Atzori, Alessio, Ruggerone, Paolo

“…The putative mechanism by which bacterial RND-type multidrug efflux pumps recognize and transport their substrates is a complex and fascinating enigma of…”
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Molecular Insights on the Recognition of Substrates by the Promiscuous Efflux Pump AcrB by Malvacio, Ivana, Ombrato, Rosella, Ruggerone, Paolo, Vargiu, Attilio V.

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Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB by Malvacio, Ivana, Buonfiglio, Rosa, D'Atanasio, Noemi, Serra, Giovanni, Bosin, Andrea, Di Giorgio, Francesco Paolo, Ruggerone, Paolo, Ombrato, Rosella, Vargiu, Attilio Vittorio

“…The drug/proton antiporter AcrB, which is part of the major efflux pump AcrABZ-TolC in Escherichia coli, is the paradigm transporter of the…”
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A new plant-based drug delivery platform based on alkyl polyglucosides and β-sitosterol nanovesicles for topical delivery by Alcaina-Hernando, Marta, Malvacio, Ivana, Ferraboschi, Ilaria, Huck-Iriart, Cristián, Bianchera, Annalisa, Sala, Santi, Pedersen, Jan Skov, Ferrer-Tasies, Lidia, Pescina, Silvia, Sissa, Cristina, Ventosa, Nora, Córdoba, Alba

“…•Novel nanovesicles without animal-derived components have been developed.•These stable nanovesicles are formed by the self-assembly of β-sitosterol, lauryl…”
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Synthesis and preliminary structure-activity relationship study of 2-aryl-2 H -pyrazolo[4,3- c ]quinolin-3-ones as potential checkpoint kinase 1 (Chk1) inhibitors by Malvacio, Ivana, Cuzzolin, Alberto, Sturlese, Mattia, Vera, D. Mariano A., Moyano, E. Laura, Moro, Stefano

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