Search Results - "Maluf, Sharbel"

Markers of genotoxicity and oxidative stress in farmers exposed to pesticides by Hilgert Jacobsen-Pereira, Carolina, dos Santos, Claudia Regina, Troina Maraslis, Flora, Pimentel, Luisi, Feijó, Ana Júlia Lobo, Iomara Silva, Clarice, de Medeiros, Guilherme da Silva, Costa Zeferino, Rodrigo, Curi Pedrosa, Rozangela, Weidner Maluf, Sharbel

“…The effects of chronic exposure to pesticides can lead to the development of several diseases, including different types of cancer, since the genotoxic and…”
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Iron supplementation does not aggravate impaired glucose tolerance and sugar overload-induced genotoxicity in rats by Molz, Patrícia, Dallemole, Danieli Rosane, Molz, Walter Augusto, Priebe Steffens, Juliana, Wildner Maluf, Sharbel, Baroni Cruz, Dennis, Rieger, Alexandre, Salvador, Mirian, Prá, Daniel, Rech Franke, Silvia Isabel

“…High sugar intake is a major risk factor for metabolic disorders. Genotoxicity is an important factor in diabetes onset, and iron (Fe) may be an aggravating…”
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Intellectual Disability in a Birth Cohort: Prevalence, Etiology, and Determinants at the Age of 4 Years by Karam, Simone M, Barros, Aluísio J D, Matijasevich, Alícia, Dos Santos, Iná S, Anselmi, Luciana, Barros, Fernando, Leistner-Segal, Sandra, Félix, Têmis M, Riegel, Mariluce, Maluf, Sharbel W, Giugliani, Roberto, Black, Maureen M

“…Intellectual disability (ID), characterized by impairments in intellectual function and adaptive behavior, affects 1-3% of the population. Many studies…”
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Genotoxic Potential and Physicochemical Parameters of Sinos River, Southern Brazil by Basso da Silva, Luciano, Maluf, Sharbel Weidner, Rodrigues, Manoela T., Kayser, Michele L., Siebel, Anna Maria, Rechenmacher, Ciliana, Scalon, Madalena C. S., Rodrigues, Marco Antonio S.

“…The present study aimed to evaluate the physicochemical parameters and the genotoxic potential of water samples collected in the upper, middle, and lower…”
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Genomic instability in human lymphocytes from male users of crack cocaine by de Freitas, Thiago Aley Brites, Palazzo, Roberta Passos, de Andrade, Fabiana Michelsen, Reichert, César Luis, Pechansky, Flávio, Kessler, Félix, de Farias, Caroline Brunetto, de Andrade, Gisele Gomes, Leistner-Segal, Sandra, Maluf, Sharbel Weidner

“…Recent research suggests that crack cocaine use alters systemic biochemical markers, like oxidative damage and inflammation markers, but very few studies have…”
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DNA Damage: Health and Longevity by Maluf, Sharbel Weidner, Martínez-López, Wilner, da Silva, Juliana

“…ATM kinase is a master regulator of the DNA damage response and is directly activated by ROS in addition to DNA double-stranded breaks. The variability of the…”
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Iron intake, red cell indicators of iron status, and DNA damage in young subjects by Prá, Daniel, Ph.D, Bortoluzzi, Angelica, B.Nutr, Müller, Luiza Louzada, B.Nutr, Hermes, Liziane, B.Nutr, Horta, Jorge André, Ph.D, Maluf, Sharbel Weidner, Ph.D, Henriques, João Antonio Pêgas, Ph.D, Fenech, Michael, Ph.D, Franke, Silvia Isabel Rech, Ph.D

“…Abstract Objective This study evaluated the association between primary DNA damage and chromosomal damage with iron intake and red blood cell parameters of…”
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Chromosome Instability and Oxidative Stress Markers in Patients with Ataxia Telangiectasia and Their Parents by Maluf, Sharbel Weidner, Prá, Daniel, Rodrigues, Graziela, Bona, Silvia, da Rosa, Darlan Pase, Jardim, Laura Bannach, Palazzo, Roberta Passos, Valiati, Victor Hugo, Bitelo Ludwig, Luciane, Marroni, Norma Anair Possa

“…Ataxia telangiectasia (AT) is a rare neurodegenerative disorder, inherited in an autosomal recessive manner. Total blood samples were collected from 20…”
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In vivo Genotoxicity of the Pyrethroid Pesticide β-Cyfluthrin Using the Comet Assay in the Fish Bryconamericus iheringii by Marinowic, Daniel R., Mergener, Michele, Pollo, Tiago A., Maluf, Sharbel W., da Silva, Luciano Basso

“…Environmental pollution by pesticide residues is a major environmental concern due to the extensive use of these substances in agriculture. The insecticide…”
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DNA damage, oxidative stress, and inflammation in children with celiac disease by Maluf, Sharbel Weidner, Wilhelm Filho, Danilo, Parisotto, Eduardo Benedetti, Medeiros, Guilherme da Silva de, Pereira, Carolina Hilgert Jacobsen, Maraslis, Flora Troina, Dornelles Schoeller, Carlos C., Rosa, Julia Savan da, Fröde, Tânia Silvia

“…The objective of this study was to evaluate the level of genomic instability in patients with celiac disease and to establish a relationship between…”
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DNA damage in blood leukocytes of individuals with sickle cell disease treated with hydroxyurea by Friedrisch, João Ricardo, Prá, Daniel, Maluf, Sharbel Weidner, Bittar, Christina Matzembacher, Mergener, Michelle, Pollo, Tiago, Kayser, Michele, da Silva, Maria Aparecida Lima, Henriques, João Antonio Pêgas, da Rocha Silla, Lucia Mariano

“…Hydroxyurea (HU) plays an important role in the treatment of patients with sickle cell disease (SCD). Although HU has been associated with an increased risk of…”
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DNA damage in children and adolescents with cardiovascular disease risk factors by Kliemann, Mariele, Prá, Daniel, Müller, Luiza L, Hermes, Liziane, Horta, Jorge A, Reckziegel, Miriam B, Burgos, Miria S, Maluf, Sharbel W, Franke, Silvia I R, Silva, Juliana da

“…The risk of developing cardiovascular disease (CVD) is related to lifestyle (e.g. diet, physical activity and smoking) as well as to genetic factors. This…”
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Are MPS II heterozygotes actually asymptomatic? A study based on clinical and biochemical data, X-inactivation analysis and imaging evaluations by de Camargo Pinto, Louise Lapagesse, Maluf, Sharbel Weidner, Leistner-Segal, Sandra, Zimmer da Silva, Camila, Brusius-Facchin, Ana, Burin, Maira Graef, Brustolin, Silvia, Llerena, Juan, Moraes, Lucia, Vedolin, Leonardo, Schuch, Alice, Giugliani, Roberto, Schwartz, Ida Vanessa Doederlein

“…For some X‐linked disorders the expressivity and penetrance in females are almost similar to those ones found in males. For mucopolysaccharidosis type II (MPS…”
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Monitoring DNA damage following radiation exposure using cytokinesis–block micronucleus method and alkaline single-cell gel electrophoresis by Maluf, Sharbel Weidner

“…The structure of DNA can be damaged as a result of exposure to ionizing radiation. Determining the frequency of chromosome aberrations is a well-known method…”
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DNA damage in peripheral blood of patients with chronic obstructive pulmonary disease (COPD) by Maluf, Sharbel Weidner, Mergener, Michelle, Dalcanale, Luciane, Costa, Cassia C., Pollo, Tiago, Kayser, Michele, da Silva, Luciano Basso, Pra, Daniel, Teixeira, Paulo José Zimermann

“…Chronic obstructive pulmonary disease (COPD) is a condition characterized by chronic airway inflammation and remodeling, lung parenchymal inflammation, and…”
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Induction and removal of DNA damage in blood leukocytes of patients with type 2 diabetes mellitus undergoing hemodialysis by Bagatini, Pamela Brambilla, Palazzo, Roberta Passos, Rodrigues, Manoela Tressoldi, Costa, Cynthia Hernandes, Maluf, Sharbel Weidner

“…Type 2 diabetes mellitus (T2DM) is associated with a high production of reactive oxygen species, which may cause oxidative DNA damage. High levels of genomic…”
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Assessment of DNA damage in lymphocytes of workers exposed to X-radiation using the micronucleus test and the comet assay by Maluf, Sharbel Weidner, Passos, Daniela Ferreira, Bacelar, Alexandre, Speit, Günter, Erdtmann, Bernardo

“…The mutagenic and carcinogenic effects of genotoxic agents on exposed people have constituted an increasing concern. Therefore, the objective of this work was…”
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Follow-up study of the genetic damage in lymphocytes of pharmacists and nurses handling antineoplastic drugs evaluated by cytokinesis-block micronuclei analysis and single cell gel electrophoresis assay by Maluf, Sharbel Weidner, Erdtmann, Bernardo

“…A follow-up study was carried out 4 years after an initial evaluation of the micronucleus frequency in 10 healthy individuals who had been occupationally…”
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A patient presenting a 22q13 deletion associated with an apparently balanced translocation t(16;22): An illustrative case in the investigation of patients with low ARSA activity by Artigalás, Osvaldo, Paskulin, Giorgio, Riegel, Mariluce, Burin, Maira, Saraiva-Pereira, Maria Luiza, Maluf, Sharbel, Kiss, Andrea, Schwartz, Ida Vanessa D

“…A 10-year-old speechless, mentally deficient male, with low arylsulfatase A (ARSA) activity, and presumably, methachromatic leukodystrophy, underwent genetic…”
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Vitamin C Intake Reduces the Cytotoxicity Associated with Hyperglycemia in Prediabetes and Type 2 Diabetes by Maluf, Sharbel Weidner, Prá, Daniel, Horta, Jorge André, Pereira, Camila Schreiner, Molz, Patrícia, Hermes, Liziane, Fishborn, Arcênio, Santos, Maria Carolina, Müller, Luiza Louzada, Franke, Silvia Isabel Rech, Wichmann, Francisca Maria Assmann

“…Hyperglycemia leads to the formation of free radicals and advanced glycation end-products (AGEs). Antioxidants can reduce the level of protein glycation and…”
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