Search Results - "Malone, Thomas C"

The Globalization of Cultural Eutrophication in the Coastal Ocean: Causes and Consequences by Malone, Thomas C., Newton, Alice

“…Coastal eutrophication caused by anthropogenic nutrient inputs is one of the greatest threats to the health of coastal estuarine and marine ecosystems…”
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A global ocean observing system framework for sustainable development by Malone, Thomas C., DiGiacomo, Paul M., Gonçalves, Emanuel, Knap, Anthony H., Talaue-McManus, Liana, de Mora, Stephen

“…Sustainable development depends on maintaining ecosystem services which are concentrated in coastal marine and estuarine ecosystems. Analyses of the science…”
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Enhancing the Global Ocean Observing System to meet evidence based needs for the ecosystem-based management of coastal ecosystem services by Malone, Thomas C., DiGiacomo, Paul M., Gonçalves, Emanuel, Knap, Anthony H., Talaue-McManus, Liana, de Mora, Stephen, Muelbert, Jose

“…Ecosystem‐based approaches (EBAs) to managing anthropogenic pressures on ecosystems, adapting to changes in ecosystem states (indicators of ecosystem health),…”
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The coastal module of the Global Ocean Observing System (GOOS): an assessment of current capabilities to detect change by Malone, Thomas C.

“…Two related topics are addressed in this paper. The first is the challenging and difficult task of producing scientifically credible quantitative assessments…”
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Iminium ion and acyliminium ion initiated cyclization reactions of vinylsilanes. Regiocontrolled synthesis of tetrahydropyridines and related heterocycles by Flann, Chris, Malone, Thomas C, Overman, Larry E

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Multiscale Experiments in Coastal Ecology: Improving Realism and Advancing Theory by PETERSEN, JOHN E, KEMP, W. MICHAEL, BARTLESON, RICK, BOYNTON, WALTER R, CHEN, CHUNG-CHI, CORNWELL, JEFFREY C, GARDNER, ROBERT H, HINKLE, DEBORAH C, HOUDE, EDWARD D, MALONE, THOMAS C, MOWITT, WILLIAM P, MURRAY, LAURA, SANFORD, LAWRENCE P, STEVENSON, J. COURT, SUNDBERG, KAREN L, SUTTLES, STEVE E

“…The Multiscale Experimental Ecosystem Research Center has conducted a series of mesocosm experiments to quantify the effects of scale—in terms of time, depth,…”
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Opportunities and Challenges of Establishing Coastal Observing Systems by Christian, Robert R., Paul M. Di Giacomo, Malone, Thomas C., Talaue-McManus, Liana

“…Some of the challenges to establishing and sustaining environmental monitoring are potentially overcome under the framework of global observing systems…”
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The coastal component of the U.S. integrated ocean observing system by MALONE, Thomas C

“…The combined effects of human activities and natural variability present significant challenges to the goals of protecting, restoring, and sustaining coastal…”
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Synthesis and pharmacological evaluation of 4a-phenanthrenamine derivatives acting at the phencyclidine binding site of the N-methyl-D-aspartate receptor complex by Bigge, Christopher F, Malone, Thomas C, Hays, Sheryl J, Johnson, Graham, Novak, Perry M, Lescosky, Leonard J, Retz, Daniel M, Ortwine, Daniel F, Probert, Albert W

“…A novel series of octahydrophenanthrenamines and their heterocyclic analogues have been synthesized as potential noncompetitive antagonists of the…”
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Synthesis and pharmacological evaluation of hexahydrofluorenamines as noncompetitive antagonists at the N-methyl-D-aspartate receptor by Hays, Sheryl J, Novak, Perry M, Ortwine, Daniel F, Bigge, Christopher F, Colbry, Norman L, Johnson, Graham, Lescosky, Leonard J, Malone, Thomas C, Michael, Andre

“…The noncompetitive (PCP) site of the N-methyl-D-aspartate (NMDA) receptor complex has been implicated in a number of pathologies, including the etiology of…”
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A pilot project to detect and forecast harmful algal blooms in the northern Gulf of Mexico by FISHER, William S, MALONE, Thomas C, GIATTINA, James D

“…More timely access to data and information on the initiation, evolution and effects of harmful algal blooms can reduce adverse impacts on valued natural…”
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Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]-quinoxaline-2,3-dione and related quinoxalinediones: characterization of .alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D-aspartate) receptor and anticonvulsant activity by Bigge, Christopher F, Malone, Thomas C, Boxer, Peter A, Nelson, Carrie B, Ortwine, Daniel F, Schelkun, Robert, Retz, Daniel M, Lescosky, Leonard J, Borosky, Susan A

“…Four related series of substituted quinoxalinediones containing angular fused-piperidine rings have been synthesized as…”
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Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists by Ortwine, Daniel F, Malone, Thomas C, Bigge, Christopher F, Drummond, James T, Humblet, Christine, Johnson, Graham, Pinter, Garry W

“…The preparation and binding affinity of a series of tetrahydroisoquinoline carboxylic acids at the N-methyl-D-aspartate (NMDA) subtype of the glutamate…”
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Microbial Biomass in the Coastal Plume of Chesapeake Bay: Phytoplankton-Bacterioplankton Relationships by Malone, Thomas C., Ducklow, Hugh W.

“…Turnover rate of suspended organic matter (POC) increased seasonally with temperature as the proportions of POC accounted for by bacterioplankton increased…”
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Synthesis of cis-4-(phosphonooxy)-2-piperidinecarboxylic acid, an N-methyl-D-aspartate antagonist by Hays, Sheryl J, Malone, Thomas C, Johnson, Graham

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Toward a National Agenda for Research in the Coastal Zone: Where Are We? by Malone, Thomas C., Nemazie, David A.

“…In response to the complex challenges of understanding and managing the effects of human activities on coastal ecosystems, the research establishment has…”
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Enhancing the G lobal O cean O bserving S ystem to meet evidence based needs for the ecosystem‐based management of coastal ecosystem services by Malone, Thomas C., DiGiacomo, Paul M., Gonçalves, Emanuel, Knap, Anthony H., Talaue‐McManus, Liana, de Mora, Stephen, Muelbert, Jose

“…Abstract Ecosystem‐based approaches ( EBAs ) to managing anthropogenic pressures on ecosystems, adapting to changes in ecosystem states (indicators of…”
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Stereocontrolled synthesis of exocyclic trisubstituted double bonds by stereospecific iminium ion-vinylsilane cyclizations. A short synthetic route to indoloquinolizidine alkaloids by Overman, Larry E, Malone, Thomas C

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GOOS regional alliances and the development of the coastal module of GOOS by Malone, Thomas C., Nowlin, Worth D.

“…Coastal nations worldwide are experiencing changes in their coastal marine and estuarine systems that jeopardize sustainable development, human health and…”
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Enhancing the Global Ocean Observing System to meet evidence based needs for the ecosystem-based management of coastal ecosystem services: Special section on oceans and seas by MALONE, Thomas C, DIGIACOMO, Paul M, GONGALVES, Emanuel, KNAP, Anthony H, TALAUE-McMANUS, Liana, DE MORA, Stephen, MUELBERT, Jose

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