Search Results - "Malone, Peter R."

The Androgen Receptor Is Significantly Associated with Vascular Endothelial Growth Factor and Hypoxia Sensing via Hypoxia-Inducible Factors HIF-1a, HIF-2a, and the Prolyl Hydroxylases in Human Prostate Cancer by BEADY, Jane L, FOX, Stephen B, CHENG HAN, CAMPO, Leticia, TURLEY, Helen, KANGA, Suresh, MALONE, Peter R, HARRIS, Adrian L

“…Purpose: Hypoxia regulates key biological processes including angiogenesis via the transcription factor, hypoxia-inducible factor (HIF). In prostate cancer,…”
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Prospective Study of Quantitation of Plasma DNA Levels in the Diagnosis of Malignant versus Benign Prostate Disease by BODDY, Jane L, GAL, Shira, MALONE, Peter R, HARRIS, Adrian L, WAINSCOAT, Jim S

“…Purpose: The aim of this study was to determine the potential of cell-free DNA levels as a diagnostic marker for prostate cancer, having first established the…”
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Restoration of the Lost Obscured Coronal Sulcus: A Novel Surgical Technique for Penile Lichen Sclerosus with Severe Preputial Adhesions by Skrodzka, Marta, Britnell, Wiliam, Ayers, Jennifer, Rea, Amanda, Morgenstern, Saskia, Hadway, Paul, Muneer, Asif, Malone, Peter R.

“…Lichen sclerosus (LS) may cause the glans and prepuce to become fused, making a standard circumcision impossible. Most authorities recommend excision of the…”
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CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma by Feber, Andrew, Worth, Daniel C, Chakravarthy, Ankur, de Winter, Patricia, Shah, Kunal, Arya, Manit, Saqib, Muhammad, Nigam, Raj, Malone, Peter R, Tan, Wei Shen, Rodney, Simon, Freeman, Alex, Jameson, Charles, Wilson, Gareth A, Powles, Tom, Beck, Stephan, Fenton, Tim, Sharp, Tyson V, Muneer, Asif, Kelly, John D

“…Other than an association with HPV infection, little is known about the genetic alterations determining the development of penile cancer. Although penile…”
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Epigenetics markers of metastasis and HPV-induced tumorigenesis in penile cancer by Feber, Andrew, Arya, Manit, de Winter, Patricia, Saqib, Muhammad, Nigam, Raj, Malone, Peter R, Tan, Wei Shen, Rodney, Simon, Lechner, Matthias, Freeman, Alex, Jameson, Charles, Muneer, Asif, Beck, Stephan, Kelly, John D

“…Penile cancer is a rare malignancy in the developed world with just more than 1,600 new cases diagnosed in the United States per year; however, the incidence…”
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Urethrocutaneous fistula: preserve the tract and turn it inside out: the PATIO repair by Malone, Peter R.

“…OBJECTIVE To describe a novel technique for repairing penile urethrocutaneous (UC) fistula, by dissecting out the fistula tract, but instead of excising it, to…”
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A tie‐over dressing for graft application in distal penectomy and glans resurfacing: the TODGA technique by Malone, Peter R., Thomas, Johanna S., Blick, Chris

“…Study Type – Therapy (case series) Level of Evidence 4 What’s known on the subject? and What does the study add? The treatment of penile cancer has been…”
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The chances of subsequent cancer detection in patients with a PSA > 20 ng/ml and an initial negative biopsy by Shaida, Nadeem, Jones, Catherine M, Ravindranath, Navin, Malone, Peter R

“…Transrectal ultrasound (TRUS)-guided prostate biopsy is known to carry a significant false-negative rate, leading some patients to have multiple biopsies. We…”
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The results of real‐time brachytherapy for the management of low‐ and intermediate‐risk prostate cancer in patients with prostate volumes up to 100 mL by Dallas, Nicola L., Malone, Peter R., Jones, Adam, Doggart, Andrew J., McConway, Kevin J., Rogers, Paul B.

“…Study Type – Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Historically, the majority of centres in the…”
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Nuclear localization of factor inhibitor hypoxia-inducible factor in prostate cancer is associated with poor prognosis by Shaida, Nadeem, Chan, Peter, Turley, Helen, Jones, Catherine M, Kanga, Suresh, Ritchie, Robert W, Malone, Peter R, Harris, Adrian L, Fox, Stephen B

“…We determined the role of factor inhibiting hypoxia-inducible factor-1 in prostate cancer specimens. A tissue microarray of 152 prostate cancers was…”
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Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the Androgen receptor in prostate cancer but is not directly regulated by Androgens or hypoxia by Banham, Alison H., Boddy, Jane, Launchbury, Rosalind, Han, Cheng, Turley, Helen, Malone, Peter R., Harris, Adrian L., Fox, Stephen B.

“…BACKGROUND FOXP1 is a member of the winged helix or forkhead transcription factors. Recent studies have indicated possible roles for FOXP1 as a candidate tumor…”
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Living with a 100 ml prostate: Outcomes over a decade by Hobbs, Catherine P, Henderson, John M, Malone, Peter R

“…Objective: The objective of this article is to determine outcomes and guide the management of patients with a prostate volume of 100 ml or greater. Patients…”
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Plastic meatotomy for pure meatal stenosis in patients with lichen sclerosus by Steffens, Joachim A., Anheuser, Petra, Treiyer, Adrian E., Reisch, Britta, Malone, Peter R.

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The role of cell-free DNA size distribution in the management of prostate cancer by Boddy, Jane L, Gal, Shira, Malone, Peter R, Shaida, Nadeem, Wainscoat, James S, Harris, Adrian L

“…Cell-free DNA has been shown to have diagnostic potential in a number of malignant diseases. Recently, the integrity or size distribution of these fragments…”
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What Is the Optimal Dose for Real-Time Prostate Brachytherapy? The Use of ESTRO/EAU/EORTC 2007 Volume Definitions to Achieve a Post Implant D90 >140 Gy by Dallas, Nicola L., FRCR, Doggart, Andrew J., M.Sc, Jones, Joanne C., M.Sc, Malone, Peter R., M.S, Jones, Adam, M.D, Rogers, Paul B., FRCR

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A Seven-Year Follow-up of Men Following a Benign Prostate Biopsy by Boddy, Jane L., Pike, Derek J., Malone, Peter R.

“…Objectives: To determine the incidence and clinical relevance of newly diagnosed cases of prostate cancer in a group of men who had an elevated PSA and benign…”
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Epigenetics markers of metastasis and HPV induced tumourigenesis in Penile cancer by Feber, Andrew, Arya, Manit, de Winter, Patricia, Saqib, Muhammad, Nigam, Raj, Malone, Peter R, Tan, Wei Shen, Rodney, Simon, Lechner, Matthias, Freeman, Alex, Jameson, Charles, Muneer, Asif, Beck, Stephan, Kelly, John D

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The results of real-time brachytherapy for the management of low- and intermediate-risk prostate cancer in patients with prostate volumes up to 100mL by Dallas, Nicola L, Malone, Peter R, Jones, Adam, Doggart, Andrew J, McConway, Kevin J, Rogers, Paul B

“…Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Historically, the majority of centres in the…”
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Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1α, HIF-2α and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines by Shaida, Nadeem, Launchbury, Rosalind, Boddy, Jane L., Jones, Catherine, Campo, Leticia, Turley, Helen, Kanga, Suresh, Banham, Alison H., Malone, Peter R., Harris, Adrian L., Fox, Stephen B.

“…Background BNIP3 is a hypoxia‐induced protein involved in cell death and survival but its role in human tumors is unclear. This study investigated the role of…”
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The number of regulatory T cells in prostate cancer is associated with the androgen receptor and hypoxia-inducible factor (HIF)-2α but not HIF-1α by Fox, Stephen B., Launchbury, Rosalind, Bates, Gaynor J., Han, Cheng, Shaida, Nadeem, Malone, Peter R., Harris, Adrian L., Banham, Alison H.

“…BACKGROUND Regulatory T cells (TR) mediate peripheral immunological tolerance and are implicated in tumor progression. Because prostate cancer is being…”
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