Search Results - "Malone, Jacob G"

Life in earth – the root microbiome to the rescue? by Mauchline, Tim H, Malone, Jacob G

“…Highlights • The soil microbiome has great potential for crop growth promotion and biocontrol. • Next generation sequencing has facilitated novel research into…”
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Plasmids manipulate bacterial behaviour through translational regulatory crosstalk by Thompson, Catriona M A, Hall, James P J, Chandra, Govind, Martins, Carlo, Saalbach, Gerhard, Panturat, Supakan, Bird, Susannah M, Ford, Samuel, Little, Richard H, Piazza, Ainelen, Harrison, Ellie, Jackson, Robert W, Brockhurst, Michael A, Malone, Jacob G

“…Beyond their role in horizontal gene transfer, conjugative plasmids commonly encode homologues of bacterial regulators. Known plasmid regulator homologues have…”
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The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways by Malone, Jacob G, Jaeger, Tina, Manfredi, Pablo, Dötsch, Andreas, Blanka, Andrea, Bos, Raphael, Cornelis, Guy R, Häussler, Susanne, Jenal, Urs

“…The genetic adaptation of pathogens in host tissue plays a key role in the establishment of chronic infections. While whole genome sequencing has opened up the…”
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Bacterial Rotary Export ATPases Are Allosterically Regulated by the Nucleotide Second Messenger Cyclic-di-GMP by Trampari, Eleftheria, Stevenson, Clare E.M., Little, Richard H., Wilhelm, Thomas, Lawson, David M., Malone, Jacob G.

“…The widespread second messenger molecule cyclic di-GMP (cdG) regulates the transition from motile and virulent lifestyles to sessile, biofilm-forming ones in a…”
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Quick change: post-transcriptional regulation in Pseudomonas by Grenga, Lucia, Little, Richard H., Malone, Jacob G.

“…Abstract Pseudomonas species have evolved dynamic and intricate regulatory networks to fine-tune gene expression, with complex regulation occurring at every…”
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The genotype of barley cultivars influences multiple aspects of their associated microbiota via differential root exudate secretion by Pacheco-Moreno, Alba, Bollmann-Giolai, Anita, Chandra, Govind, Brett, Paul, Davies, Jack, Thornton, Owen, Poole, Philip, Ramachandran, Vinoy, Brown, James K M, Nicholson, Paul, Ridout, Chris, DeVos, Sarah, Malone, Jacob G

“…Plant-associated microbes play vital roles in promoting plant growth and health, with plants secreting root exudates into the rhizosphere to attract beneficial…”
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Trehalose and α-glucan mediate distinct abiotic stress responses in Pseudomonas aeruginosa by Woodcock, Stuart D, Syson, Karl, Little, Richard H, Ward, Danny, Sifouna, Despoina, Brown, James K M, Bornemann, Stephen, Malone, Jacob G

“…An important prelude to bacterial infection is the ability of a pathogen to survive independently of the host and to withstand environmental stress. The…”
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Plant-Associated Pseudomonads by Rivilla, Rafael, Malone, Jacob G

“…Bacteria belonging to the genus (the pseudomonads) are a group of Gammaproteobacteria that are characterized by a high metabolic versatility and adaption to…”
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YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa by Malone, Jacob G, Jaeger, Tina, Spangler, Christian, Ritz, Daniel, Spang, Anne, Arrieumerlou, Cécile, Kaever, Volkhard, Landmann, Regine, Jenal, Urs

“…During long-term cystic fibrosis lung infections, Pseudomonas aeruginosa undergoes genetic adaptation resulting in progressively increased persistence and the…”
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Understanding the biosynthesis, metabolic regulation, and anti-phytopathogen activity of 3,7-dihydroxytropolone in Pseudomonas spp by Moffat, Alaster D, Höing, Lars, Santos-Aberturas, Javier, Markwalder, Tim, Malone, Jacob G, Teufel, Robin, Truman, Andrew W

“…The genus is a prolific source of specialized metabolites with significant biological activities, including siderophores, antibiotics, and plant hormones…”
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Adaptive Remodeling of the Bacterial Proteome by Specific Ribosomal Modification Regulates Pseudomonas Infection and Niche Colonisation by Little, Richard H, Grenga, Lucia, Saalbach, Gerhard, Howat, Alexandra M, Pfeilmeier, Sebastian, Trampari, Eleftheria, Malone, Jacob G

“…Post-transcriptional control of protein abundance is a highly important, underexplored regulatory process by which organisms respond to their environments…”
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A Minimal Threshold of c-di-GMP Is Essential for Fruiting Body Formation and Sporulation in Myxococcus xanthus by Skotnicka, Dorota, Smaldone, Gregory T, Petters, Tobias, Trampari, Eleftheria, Liang, Jennifer, Kaever, Volkhard, Malone, Jacob G, Singer, Mitchell, Søgaard-Andersen, Lotte

“…Generally, the second messenger bis-(3'-5')-cyclic dimeric GMP (c-di-GMP) regulates the switch between motile and sessile lifestyles in bacteria. Here, we show…”
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Cyclic di-GMP Signaling Links Biofilm Formation and Mn(II) Oxidation in Pseudomonas resinovorans by Piazza, Ainelén, Parra, Lucia, Ciancio Casalini, Lucila, Sisti, Federico, Fernández, Julieta, Malone, Jacob G, Ottado, Jorgelina, Serra, Diego O, Gottig, Natalia

“…Bioaugmentation of biological sand filters with Mn(II)-oxidizing bacteria (MOB) is used to increase the efficiency of Mn removal from groundwater. While the…”
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Biophysical and proteomic analyses of Pseudomonas syringae pv. tomato DC3000 extracellular vesicles suggest adaptive functions during plant infection by Janda, Martin, Rybak, Katarzyna, Krassini, Laura, Meng, Chen, Feitosa-Junior, Oséias, Stigliano, Egidio, Szulc, Beata, Sklenar, Jan, Menke, Frank L H, Malone, Jacob G, Brachmann, Andreas, Klingl, Andreas, Ludwig, Christina, Robatzek, Silke

“…Vesiculation is a process employed by Gram-negative bacteria to release extracellular vesicles (EVs) into the environment. EVs from pathogenic bacteria play…”
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One ligand, two regulators and three binding sites: How KDPG controls primary carbon metabolism in Pseudomonas by Campilongo, Rosaria, Fung, Rowena K Y, Little, Richard H, Grenga, Lucia, Trampari, Eleftheria, Pepe, Simona, Chandra, Govind, Stevenson, Clare E M, Roncarati, Davide, Malone, Jacob G

“…Effective regulation of primary carbon metabolism is critically important for bacteria to successfully adapt to different environments. We have identified an…”
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Pan-genome analysis identifies intersecting roles for Pseudomonas specialized metabolites in potato pathogen inhibition by Pacheco-Moreno, Alba, Stefanato, Francesca L, Ford, Jonathan J, Trippel, Christine, Uszkoreit, Simon, Ferrafiat, Laura, Grenga, Lucia, Dickens, Ruth, Kelly, Nathan, Kingdon, Alexander Dh, Ambrosetti, Liana, Nepogodiev, Sergey A, Findlay, Kim C, Cheema, Jitender, Trick, Martin, Chandra, Govind, Tomalin, Graham, Malone, Jacob G, Truman, Andrew W

“…Agricultural soil harbors a diverse microbiome that can form beneficial relationships with plants, including the inhibition of plant pathogens. spp. are one of…”
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Differential Regulation of Genes for Cyclic-di-GMP Metabolism Orchestrates Adaptive Changes During Rhizosphere Colonization by Pseudomonas fluorescens by Little, Richard H, Woodcock, Stuart D, Campilongo, Rosaria, Fung, Rowena K Y, Heal, Robert, Humphries, Libby, Pacheco-Moreno, Alba, Paulusch, Stefan, Stigliano, Egidio, Vikeli, Eleni, Ward, Danny, Malone, Jacob G

“…Bacteria belonging to the genus are highly successful colonizers of the plant rhizosphere. The ability of different species to live either commensal lifestyles…”
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Analyzing the Complex Regulatory Landscape of Hfq - an Integrative, Multi-Omics Approach by Grenga, Lucia, Chandra, Govind, Saalbach, Gerhard, Galmozzi, Carla V, Kramer, Günter, Malone, Jacob G

“…The ability of bacteria to respond to environmental change is based on the ability to coordinate, redirect and fine-tune their genetic repertoire as and when…”
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Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides by Nguyen, Don D., Melnik, Alexey V., Koyama, Nobuhiro, Lu, Xiaowen, Schorn, Michelle, Fang, Jinshu, Aguinaldo, Kristen, Lincecum, Tommie L., Ghequire, Maarten G. K., Carrion, Victor J., Cheng, Tina L., Duggan, Brendan M., Malone, Jacob G., Mauchline, Tim H., Sanchez, Laura M., Kilpatrick, A. Marm, Raaijmakers, Jos M., De Mot, René, Moore, Bradley S., Medema, Marnix H., Dorrestein, Pieter C.

“…Pseudomonads are cosmopolitan microorganisms able to produce a wide array of specialized metabolites. These molecules allow Pseudomonas to scavenge nutrients,…”
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Bacterial pathogenesis of plants: future challenges from a microbial perspective by Pfeilmeier, Sebastian, Caly, Delphine L., Malone, Jacob G.

“…Summary Future Challenges in Plant Pathology Plant infection is a complicated process. On encountering a plant, pathogenic microorganisms must first adapt to…”
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