Search Results - "Malone, Cheryl L"

Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus by Kiedrowski, Megan R, Kavanaugh, Jeffrey S, Malone, Cheryl L, Mootz, Joe M, Voyich, Jovanka M, Smeltzer, Mark S, Bayles, Kenneth W, Horswill, Alexander R

“…Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is an emerging contributor to biofilm-related infections. We recently reported that…”
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Staphopains Modulate Staphylococcus aureus Biofilm Integrity by Mootz, Joe M, Malone, Cheryl L, Shaw, Lindsey N, Horswill, Alexander R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Biofilm dispersal of community-associated methicillin-resistant Staphylococcus aureus on orthopedic implant material by Lauderdale, Katherine J., Malone, Cheryl L., Boles, Blaise R., Morcuende, Jose, Horswill, Alexander R.

“…Orthopedic implant‐related bacterial infections are associated with high morbidity that may lead to limb amputation and exert significant financial burden on…”
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Differential regulation of staphylococcal virulence by the sensor kinase SaeS in response to neutrophil-derived stimuli by Flack, Caralyn E., Zurek, Oliwia W., Meishery, Delisha D., Pallister, Kyler B., Malone, Cheryl L., Horswill, Alexander R., Voyich, Jovanka M.

“…Two-component systems (TCSs) are highly conserved across bacteria and are used to rapidly sense and respond to changing environmental conditions. The human…”
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Staphylococcus aureus Nuc2 is a functional, surface-attached extracellular nuclease by Kiedrowski, Megan R, Crosby, Heidi A, Hernandez, Frank J, Malone, Cheryl L, McNamara, 2nd, James O, Horswill, Alexander R

“…Staphylococcus aureus is a prominent bacterial pathogen that causes a diverse range of acute and chronic infections. Recently, it has been demonstrated that…”
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Proteolytic Cleavage Inactivates the Staphylococcus aureus Lipoteichoic Acid Synthase by Wörmann, Mirka E, Reichmann, Nathalie T, Malone, Cheryl L, Horswill, Alexander R, Gründling, Angelika

“…Lipoteichoic acid (LTA) is a crucial cell envelope component in Gram-positive bacteria. In Staphylococcus aureus, the polyglycerolphosphate LTA molecule is…”
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The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis by Walker, Jennifer N, Crosby, Heidi A, Spaulding, Adam R, Salgado-Pabón, Wilmara, Malone, Cheryl L, Rosenthal, Carolyn B, Schlievert, Patrick M, Boyd, Jeffrey M, Horswill, Alexander R

“…Staphylococcus aureus is a prominent bacterial pathogen that is known to agglutinate in the presence of human plasma to form stable clumps. There is increasing…”
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Biosynthesis of Staphylococcus aureus Autoinducing Peptides by Using the Synechocystis DnaB Mini-Intein by Malone, Cheryl L, Boles, Blaise R, Horswill, Alexander R

“…The Agr quorum-sensing system of Staphylococcus aureus modulates the expression of virulence factors in response to autoinducing peptides (AIPs). The peptides…”
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Modulation of Yeast Sln1 Kinase Activity by the Ccw12 Cell Wall Protein by Narang, Sandhya S., Malone, Cheryl L., Deschenes, Robert J., Fassler, Jan S.

“…The yeast Sln1p sensor kinase is best known as an osmosensor involved in the regulation of the hyperosmolarity glycerol mitogen-activated protein kinase…”
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Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy To Target Antibiotic-Resistant Infections by Todd, Daniel A, Parlet, Corey P, Crosby, Heidi A, Malone, Cheryl L, Heilmann, Kristopher P, Horswill, Alexander R, Cech, Nadja B

“…There has been major interest by the scientific community in antivirulence approaches against bacterial infections. However, partly due to a lack of viable…”
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Staphylococcus aureus metalloprotease aureolysin cleaves complement C3 to mediate immune evasion by Laarman, Alexander J, Ruyken, Maartje, Malone, Cheryl L, van Strijp, Jos A G, Horswill, Alexander R, Rooijakkers, Suzan H M

“…Complement is one of the first host defense barriers against bacteria. Activated complement attracts neutrophils to the site of infection and opsonizes…”
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Fluorescent reporters for Staphylococcus aureus by Malone, Cheryl L., Boles, Blaise R., Lauderdale, Katherine J., Thoendel, Matthew, Kavanaugh, Jeffrey S., Horswill, Alexander R.

“…With the emergence of Staphylococcus aureus as a prominent pathogen in community and healthcare settings, there is a growing need for effective reporter tools…”
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Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis by Laarman, Alexander J, Mijnheer, Gerdien, Mootz, Joe M, van Rooijen, Willemien J M, Ruyken, Maartje, Malone, Cheryl L, Heezius, Erik C, Ward, Richard, Milligan, Graeme, van Strijp, Jos A G, de Haas, Carla J C, Horswill, Alexander R, van Kessel, Kok P M, Rooijakkers, Suzan H M

“…The CXC chemokine receptor 2 (CXCR2) on neutrophils, which recognizes chemokines produced at the site of infection, plays an important role in antimicrobial…”
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A cytoplasmic coiled‐coil domain is required for histidine kinase activity of the yeast osmosensor, SLN1 by Tao, Wei, Malone, Cheryl L., Ault, Addison D., Deschenes, Robert J., Fassler, Jan S.

“…Summary The yeast histidine kinase, Sln1p, is a plasma membrane‐associated osmosensor that regulates the activity of the osmotic stress MAP kinase pathway…”
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Novel Phenol-soluble Modulin Derivatives in Community-associated Methicillin-resistant Staphylococcus aureus Identified through Imaging Mass Spectrometry by Gonzalez, David J., Okumura, Cheryl Y., Hollands, Andrew, Kersten, Roland, Akong-Moore, Kathryn, Pence, Morgan A., Malone, Cheryl L., Derieux, Jaclyn, Moore, Bradley S., Horswill, Alexander R., Dixon, Jack E., Dorrestein, Pieter C., Nizet, Victor

“…Staphylococcus aureus causes a wide range of human disease ranging from localized skin and soft tissue infections to potentially lethal systemic infections. S…”
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yeast histidine protein kinase, Sln1p, mediates phosphotransfer to two response regulators, Ssk1p and Skn7p by Li, S, Ault, A, Malone, C.L, Raitt, D, Dean, S, Johnston, L.H, Deschenes, R.J, Fassler, J.S

“…The Saccharomyces cerevisiae Sln1 protein is a ‘two‐component’ regulator involved in osmotolerance. Two‐component regulators are a family of…”
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Activated Alleles of Yeast SLN1 Increase Mcm1-dependent Reporter Gene Expression and Diminish Signaling through the Hog1 Osmosensing Pathway by Fassler, Jan S., Gray, William M., Malone, Cheryl L., Tao, Wei, Lin, Hong, Deschenes, Robert J.

“…Two-component signal transduction systems involving histidine autophosphorylation and phosphotransfer to an aspartate residue on a receiver molecule have only…”
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The Staphylococcus aureus ArIRS two-component system is a novel regulator of agglutination and pathogenesis by Walker, Jennifer N, Crosby, Heidi A, Spaulding, Adam R, Salgado-Pabon, Wilmara, Malone, Cheryl L, Rosenthal, Carolyn B, Schlievert, Patrick M, Boyd, Jeffrey M, Horswill, Alexander R

“…Staphylococcus aureus is a prominent bacterial pathogen that is known to agglutinate in the presence of human plasma to form stable clumps. There is increasing…”
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The Staphylococcus aureus ArlRS Two-Component System Is a Novel Regulator of Agglutination and Pathogenesis: e1003819 by Walker, Jennifer N, Crosby, Heidi A, Spaulding, Adam R, Salgado-Pabón, Wilmara, Malone, Cheryl L, Rosenthal, Carolyn B, Schlievert, Patrick M, Boyd, Jeffrey M, Horswill, Alexander R

“…Staphylococcus aureus is a prominent bacterial pathogen that is known to agglutinate in the presence of human plasma to form stable clumps. There is increasing…”
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Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis: CXCR2 inhibition by Staphopain A by Laarman, Alexander J, Mijnheer, Gerdien, Mootz, Joe M, van Rooijen, Willemien J M, Ruyken, Maartje, Malone, Cheryl L, Heezius, Erik C, Ward, Richard, Milligan, Graeme, van Strijp, Jos A G, de Haas, Carla J C, Horswill, Alexander R, van Kessel, Kok P M, Rooijakkers, Suzan H M

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