Search Results - "Malo, Antje"

Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection by Thomsen, Martin K., Nandakumar, Ramya, Stadler, Daniela, Malo, Antje, Valls, Roser Marin, Wang, Fan, Reinert, Line S., Dagnæs‐Hansen, Frederik, Hollensen, Anne Kruse, Mikkelsen, Jacob Giehm, Protzer, Ulrike, Paludan, Søren R.

“…Hepatitis B virus (HBV) is a major human pathogen, and about one third of the global population will be exposed to the virus in their lifetime. HBV infects…”
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Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis by Seyhun, Ersin, Malo, Antje, Schäfer, Claus, Moskaluk, Christopher A, Hoffmann, Ralf-Thorsten, Göke, Burkhard, Kubisch, Constanze H

“…In acute pancreatitis, endoplasmic reticulum (ER) stress prompts an accumulation of malfolded proteins inside the ER, initiating the unfolded protein response…”
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Interferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis by Xia, Yuchen, Stadler, Daniela, Lucifora, Julie, Reisinger, Florian, Webb, Dennis, Hösel, Marianna, Michler, Thomas, Wisskirchen, Karin, Cheng, Xiaoming, Zhang, Ke, Chou, Wen-Min, Wettengel, Jochen M, Malo, Antje, Bohne, Felix, Hoffmann, Dieter, Eyer, Florian, Thimme, Robert, Falk, Christine S, Thasler, Wolfgang E, Heikenwalder, Mathias, Protzer, Ulrike

“…Background & Aims Viral clearance involves immune cell cytolysis of infected cells. However, studies of hepatitis B virus (HBV) infection in chimpanzees have…”
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T cell receptor grafting allows virological control of Hepatitis B virus infection by Wisskirchen, Karin, Kah, Janine, Malo, Antje, Asen, Theresa, Volz, Tassilo, Allweiss, Lena, Wettengel, Jochen M, Lütgehetmann, Marc, Urban, Stephan, Bauer, Tanja, Dandri, Maura, Protzer, Ulrike

“…T cell therapy is a promising means to treat chronic HBV infection and HBV-associated hepatocellular carcinoma. T cells engineered to express an HBV-specific T…”
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4-Phenylbutyric acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini by Malo, Antje, Krüger, Burkhard, Göke, Burkhard, Kubisch, Constanze H

“…Endoplasmic reticulum (ER) stress leads to misfolded proteins inside the ER and initiates unfolded protein response (UPR). Unfolded protein response components…”
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Ethanol attenuates presentation of cytotoxic T‐lymphocyte epitopes on hepatocytes of HBV‐infected humanized mice by Ganesan, Murali, Wang, Weimin, Mathews, Saumi, Makarov, Edward, New‐Aaron, Moses, Dagur, Raghubendra Singh, Malo, Antje, Protzer, Ulrike, Kharbanda, Kusum K., Casey, Carol A., Poluektova, Larisa Y., Osna, Natalia A.

“…Background and Aims Approximately 3.5% of the global population is chronically infected with Hepatitis B Virus (HBV), which puts them at high risk of end‐stage…”
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Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection by Loffredo-Verde, Eva, Bhattacharjee, Sonakshi, Malo, Antje, Festag, Julia, Kosinska, Anna D, Ringelhan, Marc, Rim Sarkar, Sabrina, Steiger, Katja, Heikenwaelder, Mathias, Protzer, Ulrike, Prazeres da Costa, Clarissa U

“…Abstract Background Chronic hepatitis B develops more frequently in countries with high prevalence of helminth infections. The crosstalk between these 2 major…”
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Activation of cannabinoid receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms by Michler, Thomas, Storr, Martin, Kramer, Johannes, Ochs, Stefanie, Malo, Antje, Reu, Simone, Göke, Burkhard, Schäfer, Claus

“…The endocannabinoid system has been shown to mediate beneficial effects on gastrointestinal inflammation via cannabinoid receptors 1 (CB(1)) and 2 (CB(2))…”
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Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy by Müller, Thomas R., Jarosch, Sebastian, Hammel, Monika, Leube, Justin, Grassmann, Simon, Bernard, Bettina, Effenberger, Manuel, Andrä, Immanuel, Chaudhry, M. Zeeshan, Käuferle, Theresa, Malo, Antje, Cicin-Sain, Luka, Steinberger, Peter, Feuchtinger, Tobias, Protzer, Ulrike, Schumann, Kathrin, Neuenhahn, Michael, Schober, Kilian, Busch, Dirk H.

“…Adoptive transfer of T cells expressing a transgenic T cell receptor (TCR) has the potential to revolutionize immunotherapy of infectious diseases and cancer…”
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Regulation of HSP60 and the role of MK2 in a new model of severe experimental pancreatitis by Li, Yong-Yu, Ochs, Stephanie, Gao, Zhi-Rong, Malo, Antje, Chen, Chang-Jie, Lv, Shuai, Gallmeier, Eike, Göke, Burkhard, Schäfer, Claus

“…The objective of this study was to investigate the role of MAPKAP kinase 2 (MK2) and heat shock protein (HSP) HSP60 in the pathogenesis of a new model of…”
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Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis by Tietz, Anne Barbara, Malo, Antje, Diebold, Joachim, Kotlyarov, Alexey, Herbst, Andreas, Kolligs, Frank T, Brandt-Nedelev, Barbara, Halangk, Walter, Gaestel, Matthias, Göke, Burkhard, Schäfer, Claus

“…Inflammatory effects contribute to the pathogenesis of pancreatitis. Clearly, proinflammatory cytokines like TNF-alpha and IL-6 are involved in this process…”
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M1836 Acute Experimental Pancreatitis Is Ameliorated By Activation of Cannabinoid-1 (CB1) Receptors by Storr, Martin, Kramer, Johannes, Michler, Thomas, Malo, Antje, Göke, Burkhard, Schaefer, Claus

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Potential role for the narcolepsy- and multiple sclerosis-associated HLA allele DQB1 ∗0602 in schizophrenia subtypes by Großkopf, Andrea, Müller, Norbert, Malo, Antje, Wank, Rudolf

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Severity of skin reactions in erythema multiforme correlates with distinct HLA DQB1 alleles by Antje, Malo, Eckhart, Kämpgen, Rudolf, Wank

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Lack of Protection from HIV infection by the Mutant HIV Coreceptor CCR5 in Intravenously HIV Infected Hemophilia Patients by Malo, Antje, Rommel, Franz, Bogner, Johannes, Gruber, Rudi, Schramm, Wolfgang, Goebel, Frank D., Riethmüller, Gerd, Wank, Rudolf

“…The CCR5 chemokine receptor is an important coreceptor for macrophage-tropic HIV strains. Homozygous carriers of the mutated CCR5 receptor with a 32 by…”
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HIV-1-infected long-term slow progressors heterozygous for Δ32-CCR5 show significantly lower plasma viral load than wild-type slow progressors by WALLI, R, REINHART, B, LUCKOW, B, LEDERER, E, LOCH, O, MALO, A, WANK, R, SCHLÖNDORFF, D, GOEBEL, F. D

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