Search Results - "Malmström, R. E."

Effectiveness of Drugs in Routine Care: A Model for Sequential Monitoring of New Medicines Using Dronedarone as Example by Cars, T, Lindhagen, L, Malmström, RE, Neovius, M, Schwieler, J, Wettermark, B, Sundström, J

“…Although there is no doubt about the scientific value of randomized controlled clinical trials, they are usually conducted in selected populations different…”
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Rapid determination of anticoagulating effects of dabigatran in whole blood with rotational thromboelastometry and a thrombin‐based trigger by Taune, V., Skeppholm, M., Ågren, A., Gryfelt, G., Malmström, R. E., Wikman, A., Van Ryn, J., Wallén, H.

“…Essentials A rapid test to detect thrombin inhibition by dabigatran would be valuable in acute situations. A thrombin‐based trigger was applied in whole blood…”
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Thrombin‐reduced miR‐27b attenuates platelet angiogenic activities in vitro via enhancing platelet synthesis of anti‐angiogenic thrombospondin‐1 by Miao, X., Rahman, M. F.‐U., Jiang, L., Min, Y., Tan, S., Xie, H., Lee, L., Wang, M., Malmström, R. E., Lui, W.‐O., Li, N.

“…Essentials It is unclear if platelet micro‐RNAs can regulate de novo protein synthesis of platelets. Platelet de novo protein synthesis of thrombospondin‐1…”
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Influence of multiple initiatives in Sweden to enhance ARB prescribing efficiency following generic losartan; findings and implications for other countries by Godman, B, Wettermark, B, Miranda, J, Bennie, M, Martin, A, Malmström, R E

“…Encouraging the prescribing of ACEIs first line vs. angiotensin receptor blockers (ARBs) has been a health authority focus with generic ACEIs as ACEIs and ARBs…”
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l -Arginine and tetrahydrobiopterin protects against ischemia/reperfusion-induced endothelial dysfunction in patients with type 2 diabetes mellitus and coronary artery disease by Settergren, M, Böhm, F, Malmström, R.E, Channon, K.M, Pernow, J

“…Abstract Diminished levels of l -arginine and endothelial nitric oxide synthase (eNOS) uncoupling through deficiency of tetrahydrobiopterin (BH4 ) may…”
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Comparison of calibrated dilute thrombin time and aPTT tests with LC-MS/MS for the therapeutic monitoring of patients treated with dabigatran etexilate by Douxfils, J, Dogné, J-M, Mullier, F, Chatelain, B, Rönquist-Nii, Y, Malmström, R E, Hjemdahl, P

“…Ways to monitor dabigatran etexilate (DE) therapy would be useful in certain situations. Functional assays such as aPTT or Hemoclot® Thrombin Inhibitor (HTI)…”
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Influence of statin treatment on platelet inhibition by clopidogrel – a randomized comparison of rosuvastatin, atorvastatin and simvastatin co‐treatment by Malmström, R. E., Östergren, J., Jørgensen, L., Hjemdahl, P.

“… Objectives.  Possible interactions between clopidogrel and atorvastatin, simvastatin or rosuvastatin (a ‘non‐CYP3A4’ metabolized statin) were investigated in…”
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Endothelin attenuates endothelium-dependent platelet inhibition in man by Malmström, R.E, Settergren, M, Pernow, J

“…The vascular endothelium produces several substances, including nitric oxide (NO) and endothelin-1 (ET-1), which participate in the regulation of vascular tone…”
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A single test to assay warfarin, dabigatran, rivaroxaban, apixaban, unfractionated heparin, and enoxaparin in plasma by Letertre, L. R., Gudmundsdottir, B. R., Francis, C. W., Gosselin, R. C., Skeppholm, M., Malmstrom, R. E., Moll, S., Hawes, E., Francart, S., Onundarson, P. T.

“…Essentials Simple and fast assaying of different anticoagulants (ACs) is useful in emergent situations. We used highly diluted prothrombin time (dPT) or highly…”
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Different initiatives across Europe to enhance losartan utilization post generics: impact and implications by Moon, James C, Godman, Brian, Petzold, Max, Alvarez-Madrazo, Samantha, Bennett, Kathleen, Bishop, Iain, Bucsics, Anna, Hesse, Ulrik, Martin, Andrew, Simoens, Steven, Zara, Corinne, Malmström, Rickard E

“…There is an urgent need for health authorities across Europe to fully realize potential savings from increased use of generics to sustain their healthcare…”
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Nitric oxide and endothelin-1 release after one-lung ventilation during thoracoabdominal esophagectomy by Lund, M., Ny, L., Malmström, R. E., Lundberg, J. O., Öst, Å., Björnstedt, M., Lundell, L., Tsai, J. A.

“…SUMMARY One‐lung ventilation (OLV) is applied during esophagectomy to improve exposure during the thoracic part of the operation. Collapse of lung tissue,…”
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Neuropeptide Y Y1 receptor mechanisms in sympathetic vascular control by Malmström, R E

“…The Y1 receptor is the predominant vascular NPY receptor subtype in pig hind limb and kidney. Thus, vascular responses to exogenous and endogenous NPY were…”
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Poor performance with a platelet counting technique to monitor clopidogrel inhibitory effects in the point-of-care setting by Malmström, R.E, Östergren, J, Jørgensen, L, Hjemdahl, P

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Characterization and molecular cloning of vascular neuropeptide Y receptor subtypes in pig and dog by Malmström, Rickard E., Hökfelt, Tomas, Björkman, Jan-Arne, Nihlén, Carina, Byström, Mona, Ekstrand, A.Jonas, Lundberg, Jan M.

“…Cloning with subsequent in vitro and in vivo characterization of vascular neuropeptide Y (NPY) receptor subtypes in porcine and canine peripheral tissues was…”
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Existence of both neuropeptide Y, Y1 and Y2 receptors in pig spleen: evidence using subtype-selective antagonists in vivo by Malmstrom, RE

“…The effects of the first selective, non-peptide, NPY Y2 receptor antagonist…”
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Vascular neuropeptide Y Y1-receptors in the rat kidney: vasoconstrictor effects and expression of Y1-receptor mRNA by Modin, A., Malmström, R.E., Meister, B.

“…Neuropeptide Y (NPY) -receptor subtypes were studied in the rat kidney in vivo by systemic administration of NPY, the two agonists [Leu 31, Pro 34]NPY…”
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Neuropeptide Y Y1 receptor mediated mesenteric vasoconstriction in the pig in vivo by Malmstrom, RE

“…The object of the present study was to investigate the effects of the sympathetic cotransmitter neuropeptide Y (NPY), and the closely related gut hormone…”
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Sex Differences in Spontaneous Reports on Adverse Drug Events for Antihypertensive Drugs by Rydberg, D.M, Mejyr, S, Loikas, D, Schenck-Gustafsson, K, von Euler, M, Malmström, R.E

“…Methods A cross sectional analysis combining number of reports for ten groups of antihypertensive drugs; ACE inhibitors (ACE-I), with or without thiazide…”
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Vascular pharmacology of BIIE0246, the first selective non-peptide neuropeptide Y Y(2) receptor antagonist, in vivo by Malmstrom, RE

“…BIIE0246, a recently introduced non-peptide neuropeptide Y (NPY) Y(2) receptor antagonist, was pharmacologically characterized in vivo, on vascular responses…”
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Neuropeptide Y accounts for sympathetic vasoconstriction in guinea-pig vena cava: evidence using BIBP 3226 and 3435 by Malmström, Richard E., Lundberg, Jan M.

“…The ability of the novel, non-peptide, neuropeptide Y Y 1 receptor antagonist, BIBP 3226 (( R)- N 2-(diphenylacetyl)-…”
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