Search Results - "Malmierca, Mónica G."
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Volatile communication in Actinobacteria: a language for secondary metabolism regulation
Published in Microbial cell factories (18-06-2024)“…Volatile compounds are key elements in the interaction and communication between organisms at both interspecific and intraspecific levels. In complex bacterial…”
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Colibrimycins, Novel Halogenated Hybrid Polyketide Synthase-Nonribosomal Peptide Synthetase (PKS-NRPS) Compounds Produced by Streptomyces sp. Strain CS147
Published in Applied and environmental microbiology (11-01-2022)“…The improvement of genome sequencing techniques has brought to light the biosynthetic potential of actinomycetes due to the large number of gene clusters they…”
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Novel aspinolide production by Trichoderma arundinaceum with a potential role in Botrytis cinerea antagonistic activity and plant defence priming
Published in Environmental microbiology (01-04-2015)“…Summary Harzianum A (HA), a trichothecene produced by Trichoderma arundinaceum, has recently been described to have antagonistic activity against fungal plant…”
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4
Unearthing a Cryptic Biosynthetic Gene Cluster for the Piperazic Acid-Bearing Depsipeptide Diperamycin in the Ant-Dweller Streptomyces sp. CS113
Published in International journal of molecular sciences (16-02-2024)“…Piperazic acid is a cyclic nonproteinogenic amino acid that contains a hydrazine N-N bond formed by a piperazate synthase (KtzT-like). This amino acid, found…”
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Production of trichodiene by Trichoderma harzianum alters the perception of this biocontrol strain by plants and antagonized fungi
Published in Environmental microbiology (01-08-2015)“…Summary Trichothecenes are phytotoxic sesquiterpenic mycotoxins that can act as virulence factors in plant diseases. Harzianum A (HA) is a non‐phytotoxic…”
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New Sipanmycin Analogues Generated by Combinatorial Biosynthesis and Mutasynthesis Approaches Relying on the Substrate Flexibility of Key Enzymes in the Biosynthetic Pathway
Published in Applied and environmental microbiology (21-01-2020)“…The appearance of new infectious diseases, the increase in multidrug-resistant bacteria, and the need for more effective chemotherapeutic agents have oriented…”
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Cooperative Involvement of Glycosyltransferases in the Transfer of Amino Sugars during the Biosynthesis of the Macrolactam Sipanmycin by Streptomyces sp. Strain CS149
Published in Applied and environmental microbiology (15-09-2018)“…Macrolactams comprise a family of natural compounds with important bioactivities, such as antibiotic, antifungal, and antiproliferative activities. Sipanmycins…”
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Volatile Compounds in Actinomycete Communities: A New Tool for Biosynthetic Gene Cluster Activation, Cooperative Growth Promotion, and Drug Discovery
Published in Cells (Basel, Switzerland) (01-11-2022)“…The increasing appearance of multiresistant pathogens, as well as emerging diseases, has highlighted the need for new strategies to discover natural compounds…”
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Relevance of trichothecenes in fungal physiology: Disruption of tri5 in Trichoderma arundinaceum
Published in Fungal genetics and biology (01-04-2013)“…► A tri5 gene disrupted mutant was isolated. ► The tri5-disrupted mutant does not produce Harzianum A. ► Disruption of tri5 affects the expression of other key…”
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Co-Expression of Transcriptional Regulators and Housekeeping Genes in Streptomyces spp.: A Strategy to Optimize Metabolite Production
Published in Microorganisms (Basel) (15-06-2023)“…The search for novel bioactive compounds to overcome resistance to current therapeutics has become of utmost importance. spp. are one of the main sources of…”
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The Volatile Organic Compounds of Streptomyces spp.: An In-Depth Analysis of Their Antifungal Properties
Published in Microorganisms (Basel) (16-07-2023)“…The study of volatile organic compounds (VOCs) has expanded because of the growing need to search for new bioactive compounds that could be used as therapeutic…”
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Overexpression of the trichodiene synthase gene tri5 increases trichodermin production and antimicrobial activity in Trichoderma brevicompactum
Published in Fungal genetics and biology (01-03-2011)“…Trichoderma brevicompactum produces trichodermin, a simple trichothecene-type toxin that shares the first steps of the sesquiterpene biosynthetic pathway with…”
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13
Searching for Glycosylated Natural Products in Actinomycetes and Identification of Novel Macrolactams and Angucyclines
Published in Frontiers in microbiology (30-01-2018)“…Many bioactive natural products are glycosylated compounds in which the sugar components usually participate in interaction and molecular recognition of the…”
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Trichothecenes and aspinolides produced by Trichoderma arundinaceum regulate expression of Botrytis cinerea genes involved in virulence and growth
Published in Environmental microbiology (01-11-2016)“…Summary Trichoderma arundinaceum (Ta37) and Botrytis cinerea (B05.10) produce the sesquiterpenoids harzianum A (HA) and botrydial (BOT), respectively. TaΔTri5,…”
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A Multidisciplinary Approach to Unraveling the Natural Product Biosynthetic Potential of a Streptomyces Strain Collection Isolated from Leaf-Cutting Ants
Published in Microorganisms (Basel) (26-10-2021)“…The rapid emergence of bacterial resistance to antibiotics has urged the need to find novel bioactive compounds against resistant microorganisms. For that…”
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Botrydial and botcinins produced by Botrytis cinerea regulate the expression of Trichoderma arundinaceum genes involved in trichothecene biosynthesis
Published in Molecular plant pathology (01-09-2016)“…Summary Trichoderma arundinaceum IBT 40837 (Ta37) and Botrytis cinerea produce the sesquiterpenes harzianum A (HA) and botrydial (BOT), respectively, and also…”
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An Overview of Lsr2 Repressor Effect in Streptomyces spp. Secondary Metabolism
Published in Microorganisms (Basel) (14-11-2024)“…The genus Streptomyces is one of the largest producers of secondary metabolites with bioactive properties of interest. However, many of the genes involved in…”
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Volatilome: Smells like microbial spirit
Published in Advances in applied microbiology (2024)“…In recent years, the study of volatile compounds has sparked interest due to their implications in signaling and the enormous variety of bioactive properties…”
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Influence of Rhizoctonia solani and Trichoderma spp. in growth of bean (Phaseolus vulgaris L.) and in the induction of plant defense-related genes
Published in Frontiers in plant science (16-09-2015)“…Many Trichoderma species are well-known for their ability to promote plant growth and defense. We study how the interaction of bean plants with R. solani…”
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Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings
Published in Toxins (01-09-2011)“…Trichoderma brevicompactum IBT 40841 produces trichodermin, a trichothecene-type toxin that shares most of the steps of its biosynthesis with harzianum A,…”
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