Search Results - "Mallo, Diego"

Refine Results
  1. 1

    Minimal barriers to invasion during human colorectal tumor growth by Ryser, Marc D., Mallo, Diego, Hall, Allison, Hardman, Timothy, King, Lorraine M., Tatishchev, Sergei, Sorribes, Inmaculada C., Maley, Carlo C., Marks, Jeffrey R., Hwang, E. Shelley, Shibata, Darryl

    Published in Nature communications (09-03-2020)
    “…Intra-tumoral heterogeneity (ITH) could represent clonal evolution where subclones with greater fitness confer more malignant phenotypes and invasion…”
    Get full text
    Journal Article
  2. 2
  3. 3

    Evolution of Barrett’s esophagus through space and time at single-crypt and whole-biopsy levels by Martinez, Pierre, Mallo, Diego, Paulson, Thomas G., Li, Xiaohong, Sanchez, Carissa A., Reid, Brian J., Graham, Trevor A., Kuhner, Mary K., Maley, Carlo C.

    Published in Nature communications (23-02-2018)
    “…The low risk of progression of Barrett’s esophagus (BE) to esophageal adenocarcinoma can lead to over-diagnosis and over-treatment of BE patients. This may be…”
    Get full text
    Journal Article
  4. 4

    Multilocus inference of species trees and DNA barcoding by Mallo, Diego, Posada, David

    “…The unprecedented amount of data resulting from next-generation sequencing has opened a new era in phylogenetic estimation. Although large datasets should, in…”
    Get full text
    Journal Article
  5. 5

    Multilocus inference of species trees and DNA barcoding by Mallo, Diego, Posada, David

    “…The unprecedented amount of data resulting from next-generation sequencing has opened a new era in phylogenetic estimation. Although large datasets should, in…”
    Get full text
    Journal Article
  6. 6

    SimPhy: Phylogenomic Simulation of Gene, Locus, and Species Trees by Mallo, Diego, De Oliveira Martins, Leonardo, Posada, David

    Published in Systematic biology (01-03-2016)
    “…We present a fast and flexible software package—SimPhy—for the simulation of multiple gene families evolving under incomplete lineage sorting, gene duplication…”
    Get full text
    Journal Article
  7. 7

    Stronger Together: Cancer Clones Cooperate to Alleviate Growth Barriers in Critical Cancer Progression Transitions by Compton, Zachary T, Mallo, Diego, Maley, Carlo C

    Published in Cancer research (Chicago, Ill.) (15-12-2023)
    “…Hershey and colleagues recently showed how clones in a triple-negative breast cancer cell line cooperate for their mutual fitness benefit. In this system,…”
    Get full text
    Journal Article
  8. 8

    A Bayesian Supertree Model for Genome-Wide Species Tree Reconstruction by De Oliveira Martins, Leonardo, Mallo, Diego, Posada, David

    Published in Systematic biology (01-05-2016)
    “…Current phylogenomic data sets highlight the need for species tree methods able to deal with several sources of gene tree/species tree incongruence. At the…”
    Get full text
    Journal Article
  9. 9

    Abstract 2502: Genetic and functional heterogeneity of DCIS as predictors of invasive cancer by Fortunato, Angelo, Mallo, Diego, King, Lorraine, Hardman, Timothy, Hall, Allison, Marks, Jeffrey R., Hwang, Shelley Shelley, Maley, Carlo C.

    Published in Cancer research (Chicago, Ill.) (15-08-2020)
    “…Abstract Genetic diversity both between and within individual tumors constitutes a challenge to personalized cancer medicine. Intra-tumor heterogeneity…”
    Get full text
    Journal Article
  10. 10
  11. 11

    Natural Selection in Cancer Biology: From Molecular Snowflakes to Trait Hallmarks by Fortunato, Angelo, Boddy, Amy, Mallo, Diego, Aktipis, Athena, Maley, Carlo C, Pepper, John W

    “…Evolution by natural selection is the conceptual foundation for nearly every branch of biology and increasingly also for biomedicine and medical research. In…”
    Get full text
    Journal Article
  12. 12
  13. 13

    Diversity and distribution of unicellular opisthokonts along the European coast analysed using high-throughput sequencing by del Campo, Javier, Mallo, Diego, Massana, Ramon, de Vargas, Colomban, Richards, Thomas A., Ruiz-Trillo, Iñaki

    Published in Environmental microbiology (01-09-2015)
    “…Summary The opisthokonts are one of the major super groups of eukaryotes. It comprises two major clades: (i) the Metazoa and their unicellular relatives and…”
    Get full text
    Journal Article
  14. 14
  15. 15

    Abstract 2683: Ductal carcinoma in situ is a multiclonal disease by Ryser, Marc D., Sorribes, Inmaculada C., Greenwald, Matthew, Hall, Allison, Mallo, Diego, King, Lorraine M., Hardman, Timothy, Simpson, Lunden, Maley, Carlo C., Marks, Jeffrey R., Shibata, Darryl, Hwang, E. Shelley

    Published in Cancer research (Chicago, Ill.) (15-08-2020)
    “…Abstract Introduction. Ductal carcinoma in situ (DCIS) of the breast has a limited propensity to progress to invasive breast cancer. However, due to a lack of…”
    Get full text
    Journal Article
  16. 16

    Abstract PR009: Tick tock trees: Reconstructing the evolutionary dynamics of human tissues using fluctuating methylation clocks by Mallo, Diego, Bousquets-Muñoz, Pablo, Grant, Heather E., Shibata, Darryl, Graham, Trevor A., Maley, Carlo C., Gabbutt, Calum

    Published in Cancer research (Chicago, Ill.) (01-02-2024)
    “…Abstract The development of cancer from healthy somatic cells is fundamentally an evolutionary process. Understanding this process is vital to improving its…”
    Get full text
    Journal Article
  17. 17

    A new method to accurately identify single nucleotide variants using small FFPE breast samples by Fortunato, Angelo, Mallo, Diego, Rupp, Shawn M, King, Lorraine M, Hardman, Timothy, Lo, Joseph Y, Hall, Allison, Marks, Jeffrey R, Hwang, E Shelley, Maley, Carlo C

    Published in Briefings in bioinformatics (05-11-2021)
    “…Most tissue collections of neoplasms are composed of formalin-fixed and paraffin-embedded (FFPE) excised tumor samples used for routine diagnostics. DNA…”
    Get full text
    Journal Article
  18. 18
  19. 19

    Abstract A038: Evaluating DCIS progression: A comparative analysis of CNA predictive power derived from lpWGS and WES data by Iyer, Manasa, Mallo, Diego, Maley, Carlo C., Fortunato, Angelo, Cisneros, Luis, King, Lorraine M., Ryser, Marc D., Lo, Joseph Y., Hall, Allison, Marks, Jeffrey R., Hwang, Shelley

    Published in Cancer research (Chicago, Ill.) (01-02-2024)
    “…Abstract Ductal carcinoma in situ (DCIS) is a very common non-life threatening, pre-invasive form of breast cancer constituting 25% of all new breast cancer…”
    Get full text
    Journal Article
  20. 20

    Abstract B004: PISCA-box: A user-friendly interface for Phylogenetic Inference using Somatic Chromosomal Alterations (PISCA) by Grant, Heather E., Alcraft, Rachel, Bousquets-Muñoz, Pablo, Gabbutt, Calum, Berner, Alison, Yalchin, Mehmet, Maley, Carlo C., Graham, Trevor A., Mallo, Diego

    Published in Cancer research (Chicago, Ill.) (01-02-2024)
    “…Abstract PISCA, originally introduced by Martinez et al. in 2018, represents a pivotal Bayesian phylogenetics tool for the modeling of tumor evolution using…”
    Get full text
    Journal Article