Search Results - "Malleret, Benoît"
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A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development
Published in Scientific reports (14-10-2011)“…Microscopic examination of Giemsa-stained thin blood smears remains the gold standard method used to quantify and stage malaria parasites. However, this…”
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Significant biochemical, biophysical and metabolic diversity in circulating human cord blood reticulocytes
Published in PloS one (08-10-2013)“…The transition from enucleated reticulocytes to mature normocytes is marked by substantial remodeling of the erythrocytic cytoplasm and membrane. Despite…”
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CD8+ T cells and IFN-γ mediate the time-dependent accumulation of infected red blood cells in deep organs during experimental cerebral malaria
Published in PloS one (11-04-2011)“…Infection with Plasmodium berghei ANKA (PbA) in susceptible mice induces a syndrome called experimental cerebral malaria (ECM) with severe pathologies…”
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Functional and Immunologic Mapping of Domains of the Reticulocyte-Binding Protein Plasmodium vivax PvRBP2a
Published in The Journal of infectious diseases (23-09-2024)“…Abstract We previously described a novel Plasmodium vivax invasion mechanism into human reticulocytes via the PvRBP2a-CD98 receptor-ligand pair. Using linear…”
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5
cccDNA-Targeted Drug Screen Reveals a Class of Antihistamines as Suppressors of HBV Genome Levels
Published in Biomolecules (Basel, Switzerland) (24-09-2023)“…Chronic infection with hepatitis B virus (HBV) is incurable, as the current therapeutics cannot eliminate its persistent genomic material, cccDNA. Screening…”
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Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression
Published in Blood (01-12-2008)“…Plasmacytoid dendritic cells (pDCs) are antigen-presenting cells that develop into type-I interferon (IFN-I)–producing cells in response to pathogens. Their…”
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Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells
Published in Nature microbiology (01-08-2021)“…More than one-third of the world’s population is exposed to Plasmodium vivax malaria, mainly in Asia 1 . P. vivax preferentially invades reticulocytes…”
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Dynamics of T-Cell Responses and Memory T Cells during Primary Simian Immunodeficiency Virus Infection in Cynomolgus Macaques
Published in Journal of Virology (01-12-2007)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An integrated lab-on-chip for rapid identification and simultaneous differentiation of tropical pathogens
Published in PLoS neglected tropical diseases (01-07-2014)“…Tropical pathogens often cause febrile illnesses in humans and are responsible for considerable morbidity and mortality. The similarities in clinical symptoms…”
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10
Reverse transcription PCR to detect low density malaria infections
Published in Wellcome open research (2021)“…Targeted malaria elimination strategies require highly sensitive tests to detect low density malaria infections (LDMI). Commonly used methods for malaria…”
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Effect of SIVmac infection on plasmacytoid and CD1c⁺ myeloid dendritic cells in cynomolgus macaques
Published in Immunology (01-06-2008)“…Dendritic cells (DCs) are known to be essential for the induction and regulation of immune responses. Non-human primates are essential in biomedical research…”
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Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells
Published in Immunity (Cambridge, Mass.) (17-09-2019)“…Human mononuclear phagocytes comprise phenotypically and functionally overlapping subsets of dendritic cells (DCs) and monocytes, but the extent of their…”
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Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow
Published in Nature immunology (01-07-2015)“…The progenitor stage of commitment toward the conventional dendritic cell subsets and the transcriptional networks that control it remain poorly understood…”
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Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
Published in Science (American Association for the Advancement of Science) (15-03-2019)“…Macrophages are a heterogeneous cell population involved in tissue homeostasis, inflammation, and various pathologies. Although the major tissue-resident…”
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Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration
Published in Immunity (Cambridge, Mass.) (09-08-2022)“…Brain macrophage populations include parenchymal microglia, border-associated macrophages, and recruited monocyte-derived cells; together, they control brain…”
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Single-cell analysis of human skin identifies CD14+ type 3 dendritic cells co-producing IL1B and IL23A in psoriasis
Published in The Journal of experimental medicine (06-09-2021)“…Inflammatory skin diseases including atopic dermatitis (AD) and psoriasis (PSO) are underpinned by dendritic cell (DC)-mediated T cell responses. Currently,…”
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Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE
Published in Science (American Association for the Advancement of Science) (20-11-2020)“…Mast cells (MCs) are central effector cells in allergic reactions that are often mediated by immunoglobulin E (IgE). Allergies commonly start at an early age,…”
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Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax
Published in Science (American Association for the Advancement of Science) (05-01-2018)“…shows a strict host tropism for reticulocytes. We identified transferrin receptor 1 (TfR1) as the receptor for reticulocyte-binding protein 2b (PvRBP2b). We…”
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Four human Plasmodium species quantification using droplet digital PCR
Published in PloS one (19-04-2017)“…Droplet digital polymerase chain reaction (ddPCR) is a partial PCR based on water-oil emulsion droplet technology. It is a highly sensitive method for…”
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Erythrocyte tropism of malarial parasites: The reticulocyte appeal
Published in Frontiers in microbiology (26-10-2022)“…Erythrocytes are formed from the enucleation of erythroblasts in the bone marrow, and as erythrocytes develop from immature reticulocytes into mature…”
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