Search Results - "Mallat, Ziad"

Targeting the Immune System in Atherosclerosis by Zhao, Tian X., Mallat, Ziad

“…Atherosclerosis has long been known as an inflammatory disease. However, whether targeting inflammation improves outcomes was unproven until the recent results…”
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Recent Advances on the Role of Cytokines in Atherosclerosis by Ait-Oufella, Hafid, Taleb, Soraya, Mallat, Ziad, Tedgui, Alain

“…Atherosclerosis is a chronic inflammatory disease of the arterial wall driven by innate and adaptive immune responses. Inflammation controls the development…”
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Vascular smooth muscle cells in atherosclerosis by Basatemur, Gemma L., Jørgensen, Helle F., Clarke, Murray C. H., Bennett, Martin R., Mallat, Ziad

“…Vascular smooth muscle cells (VSMCs) are a major cell type present at all stages of an atherosclerotic plaque. According to the ‘response to injury’ and…”
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Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways by Tedgui, Alain, Mallat, Ziad

“…Institut National de la Santé et de la Recherche Médicale U. 689, Cardiovascular Research Center Lariboisiere, and University Paris 7, Paris, France…”
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Diabetes and aortic aneurysm: current state of the art by Raffort, Juliette, Lareyre, Fabien, Clément, Marc, Hassen-Khodja, Réda, Chinetti, Giulia, Mallat, Ziad

“…Abstract Aortic aneurysm is a life-threatening disease due to the risk of aortic rupture. The only curative treatment available relies on surgical approaches;…”
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Adaptive (T and B Cells) Immunity and Control by Dendritic Cells in Atherosclerosis by Ait-Oufella, Hafid, Sage, Andrew P, Mallat, Ziad, Tedgui, Alain

“…Chronic inflammation in response to lipoprotein accumulation in the arterial wall is central in the development of atherosclerosis. Both innate and adaptive…”
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Conflicting vascular and metabolic impact of the IL-33/sST2 axis by Altara, Raffaele, Ghali, Rana, Mallat, Ziad, Cataliotti, Alessandro, Booz, George W, Zouein, Fouad A

“…Abstract Interleukin 33 (IL-33), which is expressed by several immune cell types, endothelial and epithelial cells, and fibroblasts, is a cytokine of the IL-1…”
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Adaptive immunity in atherosclerosis: mechanisms and future therapeutic targets by Lahoute, Charlotte, Herbin, Olivier, Mallat, Ziad, Tedgui, Alain

“…Chronic inflammation of the vascular wall is a hallmark of atherosclerosis. The authors of this Review discuss the role of various T and B cell subsets in the…”
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Micro-RNAs in abdominal aortic aneurysms: insights from animal models and relevance to human disease by Raffort, Juliette, Lareyre, Fabien, Clement, Marc, Mallat, Ziad

“…Abdominal aortic aneurysm (AAA) is a major health concern and may be associated with high rates of mortality linked to acute complications. Diagnosis and…”
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Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms by Clément, Marc, Chappell, Joel, Raffort, Juliette, Lareyre, Fabien, Vandestienne, Marie, Taylor, Annabel L, Finigan, Alison, Harrison, James, Bennett, Martin R, Bruneval, Patrick, Taleb, Soraya, Jørgensen, Helle F, Mallat, Ziad

“…OBJECTIVE—Recent studies suggested the occurrence of phenotypic switching of vascular smooth muscle cells (VSMCs) during the development of aortic aneurysm…”
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Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health by Laurans, Ludivine, Venteclef, Nicolas, Haddad, Yacine, Chajadine, Mouna, Alzaid, Fawaz, Metghalchi, Sarvenaz, Sovran, Bruno, Denis, Raphael G. P., Dairou, Julien, Cardellini, Marina, Moreno-Navarrete, Jose-Maria, Straub, Marjolene, Jegou, Sarah, McQuitty, Claire, Viel, Thomas, Esposito, Bruno, Tavitian, Bertrand, Callebert, Jacques, Luquet, Serge H., Federici, Massimo, Fernandez-Real, José Manuel, Burcelin, Remy, Launay, Jean-Marie, Tedgui, Alain, Mallat, Ziad, Sokol, Harry, Taleb, Soraya

“…The association between altered gut microbiota, intestinal permeability, inflammation and cardiometabolic diseases is becoming increasingly clear but remains…”
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MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism by Li, Xuan, Thome, Sarah, Ma, Xiaodan, Amrute-Nayak, Mamta, Finigan, Alison, Kitt, Lauren, Masters, Leanne, James, John R., Shi, Yuguang, Meng, Guoyu, Mallat, Ziad

“…Excessive activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome is involved in many chronic inflammatory diseases, including…”
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Nationwide study in France investigating the impact of diabetes on mortality in patients undergoing abdominal aortic aneurysm repair by Raffort, Juliette, Lareyre, Fabien, Fabre, Roxane, Mallat, Ziad, Pradier, Christian, Bailly, Laurent

“…The aim of this nationwide study was to analyze the impact of diabetes on post-operative mortality in patients undergoing AAA repair in France. This 10-year…”
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Genetic and Pharmacological Inhibition of TREM-1 Limits the Development of Experimental Atherosclerosis by Joffre, Jeremie, MD, Potteaux, Stephane, PhD, Zeboudj, Lynda, MSc, Loyer, Xavier, PhD, Boufenzer, Amir, PhD, Laurans, Ludivine, MSc, Esposito, Bruno, BSc, Vandestienne, Marie, MSc, de Jager, Saskia C.A., MD, PhD, Hénique, Carole, PhD, Zlatanova, Ivana, MSc, Taleb, Soraya, PhD, Bruneval, Patrick, MD, PhD, Tedgui, Alain, PhD, Mallat, Ziad, MD, PhD, Gibot, Sebastien, MD, PhD, Ait-Oufella, Hafid, MD, PhD

“…Abstract Background Innate immune responses activated through myeloid cells contribute to the initiation, progression, and complications of atherosclerosis in…”
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MARK4 controls ischaemic heart failure through microtubule detyrosination by Yu, Xian, Chen, Xiao, Amrute-Nayak, Mamta, Allgeyer, Edward, Zhao, Aite, Chenoweth, Hannah, Clement, Marc, Harrison, James, Doreth, Christian, Sirinakis, George, Krieg, Thomas, Zhou, Huiyu, Huang, Hongda, Tokuraku, Kiyotaka, Johnston, Daniel St, Mallat, Ziad, Li, Xuan

“…Myocardial infarction is a major cause of premature death in adults. Compromised cardiac function after myocardial infarction leads to chronic heart failure…”
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Inhibition of MicroRNA-92a Prevents Endothelial Dysfunction and Atherosclerosis in Mice by Loyer, Xavier, Potteaux, Stéphane, Vion, Anne-Clémence, Guérin, Coralie L, Boulkroun, Sheerazed, Rautou, Pierre-Emmanuel, Ramkhelawon, Bhama, Esposito, Bruno, Dalloz, Marion, Paul, Jean-Louis, Julia, Pierre, Maccario, Jean, Boulanger, Chantal M, Mallat, Ziad, Tedgui, Alain

“…RATIONALE FOR STUDY:MicroRNAs (miRNAs) are small noncoding RNAs that regulate protein expression at post-transcriptional level. We hypothesized that a specific…”
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Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling by Santos-Zas, Icia, Lemarié, Jeremie, Zlatanova, Ivana, Cachanado, Marine, Seghezzi, Jean-Christophe, Benamer, Hakim, Goube, Pascal, Vandestienne, Marie, Cohen, Raphael, Ezzo, Maya, Duval, Vincent, Zhang, Yujiao, Su, Jin-Bo, Bizé, Alain, Sambin, Lucien, Bonnin, Philippe, Branchereau, Maxime, Heymes, Christophe, Tanchot, Corinne, Vilar, José, Delacroix, Clement, Hulot, Jean-Sebastien, Cochain, Clement, Bruneval, Patrick, Danchin, Nicolas, Tedgui, Alain, Mallat, Ziad, Simon, Tabassome, Ghaleh, Bijan, Silvestre, Jean-Sébastien, Ait-Oufella, Hafid

“…Acute myocardial infarction is a common condition responsible for heart failure and sudden death. Here, we show that following acute myocardial infarction in…”
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The role of adaptive T cell immunity in atherosclerosis by Mallat, Ziad, Taleb, Soraya, Ait-Oufella, Hafid, Tedgui, Alain

“…There is now solid evidence that T cell adaptive immunity is involved in atherogenesis. While initial studies have focused on the pathogenic arm of the immune…”
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Apoptotic Cell Death and Efferocytosis in Atherosclerosis by Van Vré, Emily A, Ait-Oufella, Hafid, Tedgui, Alain, Mallat, Ziad

“…Apoptotic cell death is an important feature of atherosclerotic plaques, and it seems to exert both beneficial and detrimental effects depending on the cell…”
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Myeloid-Epithelial-Reproductive Receptor Tyrosine Kinase and Milk Fat Globule Epidermal Growth Factor 8 Coordinately Improve Remodeling After Myocardial Infarction via Local Delivery of Vascular Endothelial Growth Factor by Howangyin, Kiave-Yune, Zlatanova, Ivana, Pinto, Cristina, Ngkelo, Anta, Cochain, Clément, Rouanet, Marie, Vilar, José, Lemitre, Mathilde, Stockmann, Christian, Fleischmann, Bernd K, Mallat, Ziad, Silvestre, Jean-Sébastien

“…BACKGROUND—In infarcted heart, improper clearance of dying cells by activated neighboring phagocytes may precipitate the transition to heart failure. We…”
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