Search Results - "Mallajosyula, Jyothi"

Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo by Chinta, Shankar J., Mallajosyula, Jyothi K., Rane, Anand, Andersen, Julie K.

“…▶ α-Syn physically localizes to dopaminergic mitochondria in vivo and impacts on mitochondrial function. ▶ Localization coincides with a selective age-related…”
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MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology by Mallajosyula, Jyothi K, Kaur, Deepinder, Chinta, Shankar J, Rajagopalan, Subramanian, Rane, Anand, Nicholls, David G, Di Monte, Donato A, Macarthur, Heather, Andersen, Julie K

“…Age-related increases in monoamine oxidase B (MAO-B) may contribute to neurodegeneration associated with Parkinson's disease (PD). The MAO-B inhibitor…”
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Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson’s disease by Siddiqui, Almas, Chinta, Shankar J., Mallajosyula, Jyothi K., Rajagopolan, Subramanian, Hanson, Ingrid, Rane, Anand, Melov, Simon, Andersen, Julie K.

“…Alpha-synuclein has been reported to be present in the nucleus and levels enhanced by oxidative stress. Herein, we sought to investigate the mechanistic role…”
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Nanoparticle encapsidation of Flock house virus by auto assembly of Tobacco mosaic virus coat protein by Maharaj, Payal D, Mallajosyula, Jyothi K, Lee, Gloria, Thi, Phillip, Zhou, Yiyang, Kearney, Christopher M, McCormick, Alison A

“…Tobacco Mosaic virus (TMV) coat protein is well known for its ability to self-assemble into supramolecular nanoparticles, either as protein discs or as rods…”
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In planta Production of Flock House Virus Transencapsidated RNA and Its Potential Use as a Vaccine by Zhou, Yiyang, Maharaj, Payal D., Mallajosyula, Jyothi K., McCormick, Alison A., Kearney, Christopher M.

“…We have developed a transencapsidated vaccine delivery system based on the insect virus, Flock House virus (FHV). FHV is attractive due to its small genome…”
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Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: Implications for early intervention on disease progression by Siddiqui, Almas, Mallajosyula, Jyothi K, Rane, Anand, Andersen, Julie K

“…Abstract We previously demonstrated that elevation of astrocytic monoamine oxidase B (MAO-B) levels in a doxycycline (dox)-inducible transgenic mouse model…”
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Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: Implications for early intervention on disease progression by Siddiqui, Almas, Mallajosyula, Jyothi K, Rane, Anand, Andersen, Julie K

“…Abstract We previously demonstrated that elevation of astrocytic monoamine oxidase B (MAO-B) levels in a doxycycline (dox)-inducible transgenic mouse model…”
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Single-dose monomeric HA subunit vaccine generates full protection from influenza challenge by Mallajosyula, Jyothi K, Hiatt, Ernie, Hume, Steve, Johnson, Ashley, Jeevan, Trushar, Chikwamba, Rachel, Pogue, Gregory P, Bratcher, Barry, Haydon, Hugh, Webby, Richard J, McCormick, Alison A

“…Recombinant subunit vaccines are an efficient strategy to meet the demands of a possible influenza pandemic, because of rapid and scalable production. However,…”
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Correction: MAO-B Elevation in Mouse Brain Astrocytes Results in Parkinson's Pathology by Mallajosyula, Jyothi K., Kaur, Deepinder, Chinta, Shankar J., Rajagopalan, Subramanian, Rane, Anand, Nicholls, David G., Di Monte, Donato A., Macarthur, Heather, Andersen, Julie K.

“…Permission has been granted by Journal of Neuroscience for the publication of this figure in the PLoS ONE article under a Creative Commons Attribution license…”
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Metabolic Control Analysis in a Cellular Model of Elevated MAO-B: Relevance to Parkinson’s Disease by Mallajosyula, Jyothi K., Chinta, Shankar J., Rajagopalan, Subramanian, Nicholls, David G., Andersen, Julie K.

“…We previously demonstrated that spare respiratory capacity of the TCA cycle enzyme alpha-ketoglutarate dehydrogenase (KGDH) was completely abolished upon…”
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Corrigendum to “Ability to delay neuropathological events associated with astrocytic MAO-B increase in a Parkinsonian mouse model: Implications for early intervention on disease progression” [Neurobiol Dis. 40/2 (2010) 444–448] by Siddiqui, Almas, Mallajosyula, Jyothi K, Rane, Anand, Andersen, Julie K

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The Genomes OnLine Database (GOLD) v.5: a metadata management system based on a four level (meta)genome project classification by Reddy, T B K, Thomas, Alex D, Stamatis, Dimitri, Bertsch, Jon, Isbandi, Michelle, Jansson, Jakob, Mallajosyula, Jyothi, Pagani, Ioanna, Lobos, Elizabeth A, Kyrpides, Nikos C

“…The Genomes OnLine Database (GOLD; http://www.genomesonline.org) is a comprehensive online resource to catalog and monitor genetic studies worldwide. GOLD…”
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Metabolic Control Analysis in a Cellular Model of Elevated MAO-B: Relevance to Parkinsonas Disease by Mallajosyula, Jyothi K, Chinta, Shankar J, Rajagopalan, Subramanian, Nicholls, David G, Andersen, Julie K

“…We previously demonstrated that spare respiratory capacity of the TCA cycle enzyme alpha-ketoglutarate dehydrogenase (KGDH) was completely abolished upon…”
Get full text