Search Results - "Malla, Sandhya"
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LSD1: Expanding Functions in Stem Cells and Differentiation
Published in Cells (Basel, Switzerland) (20-11-2021)“…Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSC) provide a powerful model system to uncover fundamental mechanisms that control cellular…”
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The scaffolding function of LSD1 controls DNA methylation in mouse ESCs
Published in Nature communications (05-09-2024)“…Lysine-specific histone demethylase 1 (LSD1), which demethylates mono- or di- methylated histone H3 on lysine 4 (H3K4me1/2), is essential for early…”
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Lipoprotein lipase in mouse kidney: effects of nutritional status and high-fat diet
Published in American journal of physiology. Renal physiology (01-03-2019)“…Activity of lipoprotein lipase (LPL) is high in mouse kidney, but the reason is poorly understood. The aim was to characterize localization, regulation, and…”
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Steering pluripotency and differentiation with N6-methyladenosine RNA modification
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-03-2019)“…Chemical modifications of RNA provide a direct and rapid way to modulate the existing transcriptome, allowing the cells to adapt rapidly to the changing…”
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Steering pluripotency and differentiation with N 6 -methyladenosine RNA modification
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-03-2019)“…Chemical modifications of RNA provide a direct and rapid way to modulate the existing transcriptome, allowing the cells to adapt rapidly to the changing…”
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Differential tissue specific expression of Kif23 alternative transcripts in mice with the human mutation causing congenital dyserythropoietic anemia type III
Published in Blood cells, molecules, & diseases (01-11-2020)“…Kinesin Family Member 23 (KIF23), a cell cycle regulator, has a key task in cytokinesis. KIF23 over-expression in cancer has been associated with tumor growth,…”
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Cooperative role of LSD1 and CHD7 in regulating differentiation of mouse embryonic stem cells
Published in Scientific reports (18-11-2024)“…Lysine-specific histone demethylase 1 (LSD1) is a histone demethylase that plays a critical role in epigenetic regulation by removing the methyl group from…”
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ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export
Published in EMBO reports (03-02-2022)“…The pluripotent state is not solely governed by the action of the core transcription factors OCT4, SOX2, and NANOG, but also by a series of co‐transcriptional…”
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Biochemical, oxidative and histological changes caused by sub-acute oral exposure of some synthetic cyanogens in rats: Ameliorative effect of α-ketoglutarate
Published in Food and chemical toxicology (01-05-2014)“…•Sub-acute oral toxicity of different cyanogens was studied in female rats.•Rats received fourteen days oral treatments of malononitrile, propionitrile or…”
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