Search Results - "Mallón, Alina Rodríguez"
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Functional and Mass Spectrometric Evaluation of an Anti-Tick Antigen Based on the P0 Peptide Conjugated to Bm86 Protein
Published in Pathogens (Basel) (25-06-2020)“…A synthetic 20 amino acid peptide of the ribosomal protein P0 from ticks, when conjugated to keyhole limpet hemocyanin from Megathura crenulata and used as an…”
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One Health Approach to Identify Research Needs on Rhipicephalus microplus Ticks in the Americas
Published in Pathogens (Basel) (13-10-2022)“…We aim to provide a harmonized view of the factors that affect the survival and promote the spread of R. microplus in the Neotropics, approaching its different…”
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Conformational and thermal stability improvements for the large-scale production of yeast-derived rabbit hemorrhagic disease virus-like particles as multipurpose vaccine
Published in PloS one (27-02-2013)“…Recombinant virus-like particles (VLP) antigenically similar to rabbit hemorrhagic disease virus (RHDV) were recently expressed at high levels inside Pichia…”
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Subunit influenza vaccine candidate based on CD154 fused to HAH5 increases the antibody titers and cellular immune response in chickens
Published in Veterinary microbiology (28-09-2011)“…World Health Organization has a great concern about the spreading of avian influenza virus H5N1. To counteract its massive spread, poultry vaccination is…”
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The Bm86 Discovery: A Revolution in the Development of Anti-Tick Vaccines
Published in Pathogens (Basel) (02-02-2023)“…The presence in nature of species with genetic resistance to ticks, or with acquired resistance after repeated tick infestations, has encouraged the scientific…”
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A chemical conjugate of the tick P0 peptide is efficacious against Amblyomma mixtum
Published in Transboundary and emerging diseases (01-07-2020)“…After Rhipicephalus microplus, the most important tick species affecting livestock industry in Cuba belong to the Amblyomma genus. There are few reports of…”
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A single dose of the novel chimeric subunit vaccine E2-CD154 confers early full protection against classical swine fever virus
Published in Vaccine (03-08-2017)“…•A stable HEK 293 cell line was generated to produce E2-CSFV antigen fused to CD154.•The E2-CD154 protein was secreted into the medium in suspension…”
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Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K carrier protein from Neisseria meningitidis
Published in Analytical and bioanalytical chemistry (01-09-2021)“…A peptide from the P0 acidic ribosomal protein (pP0) of ticks conjugated to keyhole limpet hemocyanin from Megathura crenulata has shown to be effective…”
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Exploring the impact of Anaplasma phagocytophilum on colonization resistance of Ixodes scapularis microbiota using network node manipulation
Published in Current research in parasitology & vector-borne diseases (01-01-2024)“…Upon ingestion from an infected host, tick-borne pathogens (TBPs) have to overcome colonization resistance, a defense mechanism by which tick microbiota…”
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A novel tick antigen shows high vaccine efficacy against the dog tick, Rhipicephalus sanguineus
Published in Vaccine (27-02-2012)“…Highlights ► Definition of a peptide of the tick P0 protein that confers protection against ticks. ► The R. sanguineus -rabbit model is an adequate system to…”
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High efficacy of a 20 amino acid peptide of the acidic ribosomal protein P0 against the cattle tick, Rhipicephalus microplus
Published in Ticks and tick-borne diseases (01-06-2015)“…Current strategies to control cattle ticks use integrated control programs (ICP) that include vaccination. Reduction in the use of chemicals and in the cost of…”
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Efficacy of the Vaccine Candidate Based on the P0 Peptide against Dermacentor nitens and Ixodes ricinus Ticks
Published in Pathogens (Basel) (01-11-2023)“…The control of ticks through vaccination offers a sustainable alternative to the use of chemicals that cause contamination and the selection of resistant tick…”
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Plasticity of the HEK-293 cells, related to the culture media, as platform to produce a subunit vaccine against classical swine fever virus
Published in AMB Express (05-09-2019)“…Classical swine fever (CSF) is a contagious disease that causes a high mortality to domestic and wild pigs. Its causative agent is an enveloped Pestivirus…”
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Ticks and Tick-Borne Diseases in Cuba, Half a Century of Scientific Research
Published in Pathogens (Basel) (28-07-2020)“…Ticks and the vast array of pathogens they transmit, including bacteria, viruses, protozoa, and helminths, constitute a growing burden for human and animal…”
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Developing Anti-tick Vaccines
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2016)“…Ticks are responsible for the transmission of viral, bacterial, and protozoal diseases of man and animals and also produce significant economic losses to…”
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A hydrolyzed N‐propionylthiosuccinimide linker is cleaved by metastable fragmentation, increasing reliability of conjugation site identification in conjugate vaccines
Published in Rapid communications in mass spectrometry (01-09-2024)“…RATIONALE Conjugation sites are a quality attribute of conjugate vaccines. Proteolysis of bioconjugates synthesized by maleimide–thiol chemistry generates type…”
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Differential nested patterns of Anaplasma marginale and Coxiella-like endosymbiont across Rhipicephalus microplus ontogeny
Published in Microbiological research (01-09-2024)“…Understanding the intricate ecological interactions within the microbiome of arthropod vectors is crucial for elucidating disease transmission dynamics and…”
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Competitive RT-PCR Strategy for Quantitative Evaluation of the Expression of Tilapia (Oreochromis niloticus) Growth Hormone Receptor Type I
Published in Biological procedures online (10-03-2009)“…Quantization of gene expression requires that an accurate measurement of a specific transcript is made. In this paper, a quantitative reverse…”
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CYTED Network to develop an immunogen compatible with integrated management strategies for tick control in cattle
Published in Vaccine (29-10-2018)“…INCOGARR is a thematic network recently approved to be financially supported by the Ibero-American Program of Science and Technology for Development (CYTED)…”
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Two initial vaccinations with the Bm86-based Gavacplus vaccine against Rhipicephalus (Boophilus) microplus induce similar reproductive suppression to three initial vaccinations under production conditions
Published in BMC veterinary research (16-09-2010)“…The cattle tick, Rhipicephalus (Boophilus) microplus, affects livestock production in many regions of the world. Up to now, the widespread use of chemical…”
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