Search Results - "Malkovsky, Miroslav"
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Molecular detection of human T-lymphotropic virus type 1 infection among oncology patients in Germany: A retrospective view
Published in PloS one (28-05-2019)“…Human T-cell lymphotropic virus (HTLV) belongs to a larger group of primate T-cell lymphotropic viruses (PTLVs) within the family Retroviridae. It is estimated…”
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Therapeutic Plasma Exchange–Neutralizing Antibody Combination Therapy for Severe Coronavirus Disease 2019
Published in The Journal of infectious diseases (06-07-2020)Get full text
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Cutting Edge: TGF-β1 and IL-15 Induce FOXP3+ γδ Regulatory T Cells in the Presence of Antigen Stimulation
Published in The Journal of immunology (1950) (15-09-2009)“…Abstract Several subsets of αβ regulatory T cells (Tregs) have been described and studied intensively, but the potential regulatory role of γδ T cells remains…”
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Immunological considerations underlying heat shock protein-mediated cancer vaccine strategies
Published in Immunology letters (01-01-2018)“…•Active immunotherapy has proven effective for the treatment of some types of prostate cancer.•Combination therapy involving active immunotheraputic strategies…”
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In memoriam: Paul Fisch (1959–2018) our dear friend, pioneer of γδ T cell research, esteemed scientist, and dedicated clinician
Published in Clinical & translational immunology (2019)“…In the wake of the sudden passing of Professor Paul Fisch, colleagues, collaborators and friends shared their thoughts on Paul's significant contributions to…”
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Recombinant interleukin-2 directly augments the cytotoxicity of human monocytes
Published in Nature (London) (15-01-1987)“…Interleukin-2 (IL-2), originally described as a growth factor required for sustained proliferation of T cells in vitro is a glycoprotein hormone of known…”
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Improved analysis of TCR gamma delta variable region expression in humans
Published in Journal of immunological methods (01-07-2016)“…Deeper understanding of gamma delta tau cell increases in various clinical situations requires the assessment of TCR gamma and delta variable (V) region gene…”
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Pilot trial of interleukin-2 and zoledronic acid to augment γδ T cells as treatment for patients with refractory renal cell carcinoma
Published in Cancer Immunology, Immunotherapy (01-10-2011)“…Prior to the advent of VEGF-targeted therapies, renal cell carcinoma (RCC) was among the few solid tumors shown to respond to cytokine-based therapies such as…”
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BRAF V600E Mutations in Nevi and Melanocytic Tumors of Uncertain Malignant Potential
Published in Journal of investigative dermatology (01-11-2018)Get full text
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Improved analysis of TCRγδ variable region expression in humans
Published in Journal of immunological methods (01-07-2016)“…Deeper understanding of γδ Τ cell increases in various clinical situations requires the assessment of TCRγ and δ variable (V) region gene expression and…”
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A novel thymoma-associated immunodeficiency with increased naive T cells and reduced CD247 expression
Published in The Journal of immunology (1950) (01-04-2015)“…The mechanisms underlying thymoma-associated immunodeficiency are largely unknown, and the significance of increased blood γδ Τ cells often remains elusive. In…”
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Cyclophilin A Modulates Processing of Human Immunodeficiency Virus Type 1 p55Gag: Mechanism for Antiviral Effects of Cyclosporin A
Published in Virology (New York, N.Y.) (05-06-1998)“…The molecular chaperone cyclophilin A (Cyp A) modulates human immunodeficiency virus type 1 (HIV-1) infectivity through its interactions with Gag structural…”
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Zoledronic acid and interleukin-2 treatment improves immunocompetence in HIV-infected persons by activating Vγ9Vδ2 T cells
Published in AIDS (London) (13-03-2009)Get full text
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Antiviral reactivities of γδ T cells
Published in Microbes and infection (2005)“…The complex antiviral immune mechanisms involve both adaptive and innate reactions mediated by γδ T lymphocytes, whose unique immunosurveillance contributions…”
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Drug-Induced Expansion and Differentiation of Vγ9Vδ2 T Cells In Vivo: The Role of Exogenous IL-2
Published in The Journal of immunology (1950) (01-08-2005)“…Abstract Human Vγ9Vδ2 T cells recognize nonpeptidic Ags generated by the 1-deoxy-d-xylulose 5-phosphate (many eubacteria, algae, plants, and Apicomplexa) and…”
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Therapeutic plasma exchange for the treatment of systemic sclerosis: A comprehensive review and analysis
Published in Journal of Scleroderma and Related Disorders (01-06-2018)“…Background: Therapeutic plasma exchange has been tried as a treatment approach for systemic sclerosis since 1978 based on the rationale that some circulating…”
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Histological Analysis of γδ T Lymphocytes Infiltrating Human Triple-Negative Breast Carcinomas
Published in Frontiers in immunology (10-12-2014)“…Breast cancer is the leading cause of cancer death in women and the second most common cancer worldwide after lung cancer. The remarkable heterogeneity of…”
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Drug-induced expansion and differentiation of V gamma 9V delta 2 T cells in vivo: the role of exogenous IL-2
Published in The Journal of immunology (1950) (01-08-2005)“…Human Vgamma9Vdelta2 T cells recognize nonpeptidic Ags generated by the 1-deoxy-d-xylulose 5-phosphate (many eubacteria, algae, plants, and Apicomplexa) and…”
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Anti-severe acute respiratory syndrome coronavirus immune responses: the role played by V gamma 9V delta 2 T cells
Published in The Journal of infectious diseases (01-05-2006)“…Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus (SARS-CoV) strain. Analyses of T cell repertoires in health care workers who survived…”
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Anti–Severe Acute Respiratory Syndrome Coronavirus Immune Responses: The Role Played by Vγ9Vδ2 T Cells
Published in The Journal of infectious diseases (01-05-2006)“…Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus (SARS-CoV) strain. Analyses of T cell repertoires in health care workers who survived…”
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