Search Results - "Malkov, Andrei V."

Highly Stereoselective Synthesis of Z-Homoallylic Alcohols by Kinetic Resolution of Racemic Secondary Allyl Boronates by Incerti-Pradillos, Celia A., Kabeshov, Mikhail A., Malkov, Andrei V.

“…α to Z: Racemic α‐chiral allyl boronates, which are readily synthesized from the respective primary allyl halides, undergo a highly efficient kinetic…”
Get full text

3-Chlorooxindoles: Versatile Starting Materials for Asymmetric Organocatalytic Synthesis of Spirooxindoles by Noole, Artur, Ošeka, Maksim, Pehk, Tõnis, Öeren, Mario, Järving, Ivar, Elsegood, Mark R. J., Malkov, Andrei V., Lopp, Margus, Kanger, Tõnis

“…3‐Chlorooxoindoles have emerged as versatile precursors in the synthesis of spirocyclopropyl oxindoles. High enantio‐ and diastereoselectivity was attained…”
Get full text

Highly Enantio- and Diastereoselective Generation of Two Quaternary Centers in Spirocyclopropanation of Oxindole Derivatives by Noole, Artur, Sucman, Natalia S., Kabeshov, Mikhail A., Kanger, Tõnis, Macaev, Fliur Z., Malkov, Andrei V.

“…Spirocyclopropanes: Only one out of eight possible stereoisomers was obtained in the asymmetric cascade cyclopropanation of alkylidene oxindoles with ethyl…”
Get full text

Enantioselective Synthesis of 1,2-Diarylaziridines by the Organocatalytic Reductive Amination of α-Chloroketones by Malkov, Andrei V., Stončius, Sigitas, Kočovský, Pavel

“…One‐sided triangles: A simple protocol has been developed for the synthesis of highly useful single enantiomers of 1,2‐diarylaziridines. The method involves…”
Get full text

Vicinal Amino Alcohols as Organocatalysts in Asymmetric Cross-Aldol Reaction of Ketones:  Application in the Synthesis of Convolutamydine A by Malkov, Andrei V, Kabeshov, Mikhail A, Bella, Marco, Kysilka, Ondřej, Malyshev, Denis A, Pluháčková, Kristýna, Kočovský, Pavel

“…Leucinol and valinol have been identified as efficient organocatalysts for the aldol reaction of isatin and its derivatives (as examples of activated,…”
Get full text

Dynamic Kinetic Resolution in the Asymmetric Synthesis of β-Amino Acids by Organocatalytic Reduction of Enamines with Trichlorosilane by Malkov, Andrei V., Stončius, Sigitas, Vranková, Kvetoslava, Arndt, Matthias, Kočovský, Pavel

“…Resolved dynamically: A new, expedient protocol has been developed for the asymmetric synthesis of β3‐ and β2, 3‐amino acid derivatives from enamine precursors…”
Get full text

Intramolecular Carbonyl Nitroso Ene Reaction Catalyzed by Iron(III) Chloride/Hydrogen Peroxide as an Efficient Tool for Direct Allylic Amination by Atkinson, Duncan, Kabeshov, Mikhail A., Edgar, Mark, Malkov, Andrei V.

“…A mild, simple oxidation protocol employing iron(III) chloride as a catalyst and hydrogen peroxide as a stoichiometric oxidant was found to be compatible with…”
Get full text

Vanadium-Catalyzed Asymmetric Epoxidation of Allylic Alcohols in Water by Malkov, Andrei V, Czemerys, Louise, Malyshev, Denis A

“…Asymmetric V-catalyzed epoxidation of allylic alcohols can be carried out in water with chiral ligands, which incorporate sulfonamide and hydroxamic acid…”
Get full text

Catalytic Asymmetric Crotylation of Aldehydes: Application in Total Synthesis of (−)-Elisabethadione by O'Hora, Paul S., Incerti-Pradillos, Celia A., Kabeshov, Mikhail A., Shipilovskikh, Sergei A., Rubtsov, Aleksandr E., Elsegood, Mark R. J., Malkov, Andrei V.

“…A new, highly efficient Lewis base catalyst for a practical enantio‐ and diastereoselective crotylation of unsaturated aldehydes with E‐ and…”
Get full text

A Novel Bifunctional Allyldisilane as a Triple Allylation Reagent in the Stereoselective Synthesis of Trisubstituted Tetrahydrofurans by Malkov, Andrei V., Kysilka, Ondřej, Edgar, Mark, Kadlčíková, Aneta, Kotora, Martin, Kočovský, Pavel

“…Three for the price of two: A bifunctional allyldisilane undergoes a two‐step triple allylation sequence with pairs of aldehydes to give all‐cis trisubstituted…”
Get full text

Palladium-Catalyzed Stereoselective Intramolecular Oxidative Amidation of Alkenes in the Synthesis of 1,3- and 1,4-Amino Alcohols and 1,3-Diamines by Malkov, Andrei V., Lee, Darren S., Barłóg, Maciej, Elsegood, Mark R. J., Kočovský, Pavel

“…An efficient and practical Pd‐catalyzed intramolecular oxidative allylic amidation provides facile access to derivatives of 1,3‐ and 1,4‐amino alcohols and…”
Get full text

Harnessing Applied Potential: Selective β‑Hydrocarboxylation of Substituted Olefins by Alkayal, Anas, Tabas, Volodymyr, Montanaro, Stephanie, Wright, Iain A, Malkov, Andrei V, Buckley, Benjamin R

“…The construction of carboxylic acid compounds in a selective fashion from low value materials such as alkenes remains a long-standing challenge to synthetic…”
Get full text

Enantioselective and Catalytic Method for α‐Crotylation of Aldehydes with a Kinetic Self‐Refinement of Stereochemistry by Malkov, Andrei V., Kabeshov, Mikhail A., Barłog, Maciej, Kočovský, Pavel

“…Kinetic refinery: A practical, highly stereoselective, two‐step catalytic protocol for the α‐allylation of aldehydes, starting from crotyltrichlorosilanes, has…”
Get full text

Selective Electrosynthetic Hydrocarboxylation of α,β‐Unsaturated Esters with Carbon Dioxide by Sheta, Ahmed M., Alkayal, Anas, Mashaly, Mohammad A., Said, Samy B., Elmorsy, Saad S., Malkov, Andrei V., Buckley, Benjamin R.

“…The carboxylation of low‐value commodity chemicals to provide higher‐value carboxylic acids is of significant interest. Recently alternative routes to the…”
Get full text

Asymmetric Allylic Substitution Catalyzed by C1-Symmetrical Complexes of Molybdenum: Structural Requirements of the Ligand and the Stereochemical Course of the Reaction by Malkov, Andrei V., Gouriou, Laure, Lloyd-Jones, Guy C., Starý, Ivo, Langer, Vratislav, Spoor, Paul, Vinader, Victoria, Kočovský, Pavel

“…Application of new chiral ligands (R)‐(−)‐12 a and (S)‐(+)‐12 c (VALDY), derived from amino acids, to the title reaction, involving cinnamyl (linear) and…”
Get full text

New Lewis-Basic N-Oxides as Chiral Organocatalysts in Asymmetric Allylation of Aldehydes by Malkov, Andrei V, Bell, Mark, Orsini, Monica, Pernazza, Daniele, Massa, Antonio, Herrmann, Pavel, Meghani, Premji, Kočovský, Pavel

“…Allylation of aromatic and heteroaromatic aldehydes 1a − k with allyltrichlorosilane 2 can be catalyzed by the new heterobidentate, terpene-derived bipyridine…”
Get full text

Soluble Polymer‐Supported Organocatalysts: Asymmetric Reduction of Imines with Trichlorosilane Catalyzed by an Amino Acid Derived Formamide Anchored to a Soluble Polymer by Malkov, Andrei V., Figlus, Marek, Prestly, Mark R., Rabani, Gouher, Cooke, Graeme, Kočovský, Pavel

“…A novel polymeric platform for catalyst immobilization has been developed, featuring inverted solubility pattern: soluble in a nonpolar and insoluble in a…”
Get full text

A Mild Method for Electrochemical Reduction of Heterocyclic N‐Oxides by Fukazawa, Yasuaki, Rubtsov, Aleksandr E., Malkov, Andrei V.

“…Deoxygenation of heteroaromatic N‐oxides is commonly accomplished using chemical or enzymatic methods. In this work, we report on an expedient protocol for…”
Get full text

Dehydration of Amides to Nitriles under Conditions of a Catalytic Appel Reaction by Shipilovskikh, Sergei A, Vaganov, Vladimir Yu, Denisova, Elena I, Rubtsov, Aleksandr E, Malkov, Andrei V

“…A highly expedient protocol for a catalytic Appel-type dehydration of amides to nitriles has been developed that employs oxalyl chloride and triethylamine…”
Get full text

Chiral N-Oxides in Asymmetric Catalysis by Malkov, Andrei V., Kočovský, Pavel

“…This microreview highlights the utilization of chiral amine N‐oxides in catalytic asymmetric transformations, which are discussed in a more general context of…”
Get full text