Search Results - "Malka, Assaf"
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Controlling autoimmune diabetes onset by targeting Protease-Activated Receptor 2
Published in Biomedicine & pharmacotherapy (01-06-2024)“…Type 1 diabetes (T1D) is a challenging autoimmune disease, characterized by an immune system assault on insulin-producing β-cells. As insulin facilitates…”
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The mitochondria as a target for cardioprotection in acute myocardial ischemia
Published in Pharmacology & therapeutics (Oxford) (01-04-2014)“…The ischemic heart suffers from nutrient deprivation, lack of oxygen, metabolic acidosis, hyperkalemia and Ca(2+) overload as well as high level of reactive…”
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3
Gestational diabetes induces behavioral and brain gene transcription dysregulation in adult offspring
Published in Translational psychiatry (25-11-2020)“…The etiology of Autism Spectrum Disorders (ASD) includes a strong genetic component and a complicated environmental component. Recent evidence indicates that…”
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4
Modified Snake α-Neurotoxin Averts β-Amyloid Binding to α7 Nicotinic Acetylcholine Receptor and Reverses Cognitive Deficits in Alzheimer’s Disease Mice
Published in Molecular neurobiology (01-05-2021)“…Alzheimer’s disease (AD) is the most common cause of senile dementia and one of the greatest medical, social, and economic challenges. According to a dominant…”
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5
Resolving the conflicts around Par2 opposing roles in regeneration by comparing immune-mediated and toxic-induced injuries
Published in Inflammation and Regeneration (29-11-2022)“…Abstract Background Different factors may lead to hepatitis. Among which are liver inflammation and poisoning. We chose two hepatitis models, typical for these…”
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The cardioprotective efficacy of TVP 1022 against ischemia/reperfusion injury and cardiac remodeling in rats
Published in Pharmacology research & perspectives (01-12-2016)“…Following acute myocardial infarction (MI), early and successful reperfusion is the most effective strategy for reducing infarct size and improving the…”
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7
ChiTaRS-3.1-the enhanced chimeric transcripts and RNA-seq database matched with protein-protein interactions
Published in Nucleic acids research (04-01-2017)“…Discovery of chimeric RNAs, which are produced by chromosomal translocations as well as the joining of exons from different genes by trans-splicing, has added…”
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P systems with protein rules
Published in Journal of the Franklin Institute (01-05-2022)“…Membrane computing or P-systems is a subfield of natural computing, which models living systems with mathematical tools. In classical membrane-computing, cells…”
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Opposite PAR2 roles in liver regeneration from autoimmune or direct damage. Solving the conflict
Published in Journal of hepatology (01-07-2022)Get full text
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Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production
Published in Diabetologia (01-10-2023)“…Aim/hypothesis Hyperglycaemia is associated with alpha cell dysfunction, leading to dysregulated glucagon secretion in type 1 and type 2 diabetes; however, the…”
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Layer-specific strain analysis: investigation of regional deformations in a rat model of acute versus chronic myocardial infarction
Published in American journal of physiology. Heart and circulatory physiology (01-09-2012)“…Myocardial infarction (MI) injury extends from the endocardium toward the epicardium. This phenomenon should be taken into consideration in the detection of…”
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Detection of small subendocardial infarction using speckle tracking echocardiography in a rat model
Published in Echocardiography (Mount Kisco, N.Y.) (01-10-2016)“…Background It is challenging to detect small nontransmural infarcts visually or automatically. As it is important to detect myocardial infarction (MI) at early…”
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Strain Analysis in the Detection of Myocardial Infarction at the Acute and Chronic Stages
Published in Echocardiography (Mount Kisco, N.Y.) (01-03-2016)“…Background Myocardial ischemia causes contractile dysfunction in ischemic, stunned, and tethered regions with larger infarcted zones having a negative…”
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TVP1022: A Novel Cardioprotective Drug Attenuates Left Ventricular Remodeling After Ischemia/Reperfusion in Pigs
Published in Journal of cardiovascular pharmacology (01-08-2015)“…BACKGROUND:The current cornerstone treatment of myocardial infarction (MI) is restoration of coronary blood flow by means of thrombolytic therapy or primary…”
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15
The cardioprotective efficacy of TVP1022 against ischemia/reperfusion injury and cardiac remodeling in rats
Published in Pharmacology research & perspectives (01-12-2016)“…Following acute myocardial infarction (MI), early and successful reperfusion is the most effective strategy for reducing infarct size and improving the…”
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