Search Results - "Malissen, Nausicaa"

Clinical Features, Management, and Outcomes of Immune Checkpoint Inhibitor-Related Cardiotoxicity by Escudier, Marion, Cautela, Jennifer, Malissen, Nausicaa, Ancedy, Yann, Orabona, Morgane, Pinto, Johan, Monestier, Sandrine, Grob, Jean-Jacques, Scemama, Ugo, Jacquier, Alexis, Lalevee, Nathalie, Barraud, Jeremie, Peyrol, Michael, Laine, Marc, Bonello, Laurent, Paganelli, Franck, Cohen, Ariel, Barlesi, Fabrice, Ederhy, Stephane, Thuny, Franck

“…Immune checkpoint inhibitors (ICIs) represent a major advance in the treatment of cancer. Although clinical trials reported a low incidence of immune-related…”
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Long-term treatment of cutaneous manifestations of tuberous sclerosis complex with topical 1% sirolimus cream: A prospective study of 25 patients by Malissen, Nausicaa, MD, Vergely, Laurence, PharmD, Simon, Marguerite, PharmD, Roubertie, Agathe, MD, PhD, Malinge, Marie-Claire, MD, Bessis, Didier, MD

“…Background Data on long-term topical sirolimus treatment of the cutaneous manifestations of tuberous sclerosis complex are rare. Objective To evaluate the…”
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Cross-cultural adaptation into French and validation of the SCAR-Q questionnaire by Radulesco, Thomas, Mancini, Julien, Penicaud, Martin, Grob, Jean-Jacques, Richard, Marie-Aleth, Dessi, Patrick, Malissen, Nausicaa, Michel, Justin

“…Purpose Most questionnaires designed to evaluate patient-reported outcomes regarding scarring are available in English. The objective was to generate a…”
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HVEM has a broader expression than PD-L1 and constitutes a negative prognostic marker and potential treatment target for melanoma by Malissen, Nausicaa, Macagno, Nicolas, Granjeaud, Samuel, Granier, Clémence, Moutardier, Vincent, Gaudy-Marqueste, Caroline, Habel, Nadia, Mandavit, Marion, Guillot, Bernard, Pasero, Christine, Tartour, Eric, Ballotti, Robert, Grob, Jean-Jacques, Olive, Daniel

“…HVEM (Herpes Virus Entry Mediator) engagement of BTLA (B and T Lymphocyte Attenuator) triggers inhibitory signals in T cells and could play a role in evading…”
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Diabetes and Blood Glucose Disorders Under Anti-PD1 by Magis, Quentin, Gaudy-Marqueste, Caroline, Basire, Agnes, Loundou, Anderson, Malissen, Nausicaa, Troin, Laura, Monestier, Sandrine, Mallet, Stéphanie, Hesse, Sylvie, Richard, Marie-Aleth, Valéro, René, Beliard, Sophie, Grob, Jean-Jacques

“…Acute type 1 diabetes (AD1) is a rare but definitive immune-related adverse event associated with anti-PD1. Most of the reported cases are close to what has…”
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Clinical Impact of High Throughput Sequencing on Liquid Biopsy in Advanced Solid Cancer by Gouton, Etienne, Malissen, Nausicaa, André, Nicolas, Jeanson, Arnaud, Pelletier, Annick, Testot-Ferry, Albane, Gaudy-Marqueste, Caroline, Dahan, Laetitia, Tabouret, Emeline, Chevalier, Thomas, Greillier, Laurent, Tomasini, Pascale

“…Cancer therapies targeting actionable molecular alterations (AMA) have developed, but the clinical routine impact of high-throughput molecular profiling…”
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Early Phase of Primary Melanoma Growth from the Patient Point of view: A Prospective Cross Sectional Study on Melanoma over 1 mm in Thickness by Malissen, N, Abed, S, Macagno, N, Amatore, F, Loundou, A, Grange, F, Gaudy-Marqueste, C, Grob, J

“…Most melanomas are diagnosed by the patients themselves or by their partners or relatives; they alone can describe its history. We designed a prospective…”
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Study of metastatic kinetics in metastatic melanoma treated with B-RAF inhibitors: Introducing mathematical modelling of kinetics into the therapeutic decision by Hartung, Niklas, Huynh, Cécilia T-K, Gaudy-Marqueste, Caroline, Flavian, Antonin, Malissen, Nausicaa, Richard-Lallemand, Marie-Aleth, Hubert, Florence, Grob, Jean-Jacques

“…Evolution of metastatic melanoma (MM) under B-RAF inhibitors (BRAFi) is unpredictable, but anticipation is crucial for therapeutic decision. Kinetics changes…”
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The scalp hair collar and tuft signs: A retrospective multicenter study of 78 patients with a systematic review of the literature by Bessis, Didier, MD, Bigorre, Michèle, MD, Malissen, Nausicaa, MD, Captier, Guillaume, MD, PhD, Chiaverini, Christine, MD, Abasq, Claire, MD, Barbarot, Sébastien, MD, PhD, Boccara, Olivia, MD, Bourrat, Emmanuelle, MD, El Fertit, Hassan, MD, Eschard, Catherine, MD, Hubiche, Thomas, MD, Lacour, Jean-Philippe, MD, PhD, Leboucq, Nicolas, MD, Mahé, Emmanuel, MD, PhD, Mallet, Stéphanie, MD, Marque, Myriam, MD, Martin, Ludovic, MD, PhD, Mazereeuw-Hautier, Juliette, MD, PhD, Milla, Nathalie, MD, Phan, Alice, MD, PhD, Plantin, Patrice, MD, Picot, Marie-Christine, MD, PhD, Puzenat, Eve, MD, Rigau, Valérie, MD, PhD, Vabres, Pierre, MD, PhD, Fraitag, Sylvie, MD, Boralevi, Franck, MD, PhD

“…Background Hair collar sign (HCS) and hair tuft of the scalp (HTS) are cutaneous signs of an underlying neuroectodermal defect, but most available data are…”
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Metastatic Melanoma: Recent Therapeutic Progress and Future Perspectives by Malissen, Nausicaa, Grob, Jean-Jacques

“…The prognosis of patients with metastatic melanoma has dramatically improved in recent years with the introduction of two new therapeutic strategies. BRAF and…”
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Treatment of Recurrent Melanoma Following Adjuvant Therapy by Malissen, Nausicaa, Grob, Jean-Jacques

“…In the era of effective therapies in melanoma, notably the widespread use of two types of adjuvant treatments: anti-PD-1 immunotherapies and therapies…”
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Mathematical modeling of routine biological parameters kinetics in order to predict durable benefit for first-line immunotherapy in metastatic or unresectable melanoma by Forestier, Jessica, Daumas, Alice Julie, Richard, Marie-Aleth, Gaudy-Marqueste, Caroline, Benzekry, Sebastien, Malissen, Nausicaa

“…e21549 Background: PD1, CTLA4 and LAG3 blockade have shown remarkable efficacy in melanoma patients. Predictive biomarkers are needed to predict response,…”
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Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification by Leader, Andrew M., Grout, John A., Maier, Barbara B., Nabet, Barzin Y., Park, Matthew D., Tabachnikova, Alexandra, Chang, Christie, Walker, Laura, Lansky, Alona, Le Berichel, Jessica, Troncoso, Leanna, Malissen, Nausicaa, Davila, Melanie, Martin, Jerome C., Magri, Giuliana, Tuballes, Kevin, Zhao, Zhen, Petralia, Francesca, Samstein, Robert, D’Amore, Natalie Roy, Thurston, Gavin, Kamphorst, Alice O., Wolf, Andrea, Flores, Raja, Wang, Pei, Müller, Sören, Mellman, Ira, Beasley, Mary Beth, Salmon, Hélène, Rahman, Adeeb H., Marron, Thomas U., Kenigsberg, Ephraim, Merad, Miriam

“…Immunotherapy is a mainstay of non-small cell lung cancer (NSCLC) management. While tumor mutational burden (TMB) correlates with response to immunotherapy,…”
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Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma by Magen, Assaf, Hamon, Pauline, Fiaschi, Nathalie, Soong, Brian Y., Park, Matthew D., Mattiuz, Raphaël, Humblin, Etienne, Troncoso, Leanna, D’souza, Darwin, Dawson, Travis, Kim, Joel, Hamel, Steven, Buckup, Mark, Chang, Christie, Tabachnikova, Alexandra, Schwartz, Hara, Malissen, Nausicaa, Lavin, Yonit, Soares-Schanoski, Alessandra, Giotti, Bruno, Hegde, Samarth, Ioannou, Giorgio, Gonzalez-Kozlova, Edgar, Hennequin, Clotilde, Le Berichel, Jessica, Zhao, Zhen, Ward, Stephen C., Fiel, Isabel, Kou, Baijun, Dobosz, Michael, Li, Lianjie, Adler, Christina, Ni, Min, Wei, Yi, Wang, Wei, Atwal, Gurinder S., Kundu, Kunal, Cygan, Kamil J., Tsankov, Alexander M., Rahman, Adeeb, Price, Colles, Fernandez, Nicolas, He, Jiang, Gupta, Namita T., Kim-Schulze, Seunghee, Gnjatic, Sacha, Kenigsberg, Ephraim, Deering, Raquel P., Schwartz, Myron, Marron, Thomas U., Thurston, Gavin, Kamphorst, Alice O., Merad, Miriam

“…Despite no apparent defects in T cell priming and recruitment to tumors, a large subset of T cell rich tumors fail to respond to immune checkpoint blockade…”
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Safety and immunogenicity after 2 doses of the BNT162b2 COVID-19 vaccine in an early-phase oncology trial centre population by Malissen, Nausicaa, Ninove, Laetitia, de Lamballerie, Xavier, André, Nicolas, Gaudy-Marqueste, Caroline

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Loss of H3K27 trimethylation is not suitable for distinguishing malignant peripheral nerve sheath tumor from melanoma: a study of 387 cases including mimicking lesions by Le Guellec, Sophie, Macagno, Nicolas, Velasco, Valérie, Lamant, Laurence, Lae, Marick, Filleron, Thomas, Malissen, Nausicaa, Cassagnau, Elisabeth, Terrier, Philippe, Chevreau, Christine, Ranchere-Vince, Dominique, Coindre, Jean-Michel

“…The diagnosis of malignant peripheral nerve sheath tumor remains challenging, especially in the sporadic setting. Malignant peripheral nerve sheath tumor is a…”
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Stereotactic radiosurgery combined with anti-PD1 for the management of melanoma brain metastases: A retrospective study of safety and efficacy by Carron, Romain, Gaudy-Marqueste, Caroline, Amatore, Florent, Padovani, Laetitia, Malissen, Nausicaa, Balossier, Anne, Loundou, Anderson, Bonnet, Nathalie, Muracciole, Xavier, Régis, Jean-Marie, Grob, Jean-Jacques

“…Brain metastases can be effectively treated with stereotactic radiosurgery (SRS). Immune checkpoint inhibitors are now pivotal in metastatic melanoma care, but…”
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Clinical benefit of personalized treatment following high throughput sequencing in metastatic melanoma: A national retrospective study by Connell, Emily, Gérard, Emilie, Oules, Bénédicte, Brunet-Possenti, Florence, Lamoureux, Anouck, Bonnefille, Hugo, Mary-Prey, Sorilla, Mouret, Stéphane, Kramkimel, Nora, Lesage, Candice, Stoebner, Pierre-Emmanuel, Jeanson, Arnaud, Ouafik, L’houcine, Gaudy-Marqueste, Caroline, Tomasini, Pascale, Charles, Julie, Amini Adle, Mona, Malissen, Nausicaa

“…e21534 Background: Despite the approval of effective therapies in metastatic melanoma, durable benefit concerns only a fraction of patients and new therapeutic…”
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Macrophage activation syndrome: A new complication of checkpoint inhibitors by Malissen, Nausicaa, Lacotte, Julie, Du-Thanh, Aurélie, Gaudy-Marqueste, Caroline, Guillot, Bernard, Grob, Jean-Jacques

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Molecularly matched targeted therapy: a promising approach for refractory metastatic melanoma by Connell, Emily, Gerard, Émilie, Oules, Bénédicte, Brunet-Possenti, Florence, Lamoureux, Anouck, Bonnefille, Hugo, Mary-Prey, Sorilla, Carrasquilla, Ana, Mouret, Stéphane, Kramkimel, Nora, Lesage, Candice, Stoebner, Pierre-Emmanuel, Bartoli, Axel, Monestier, Sandrine, Correard, Florian, Gros, Audrey, Jeanson, Arnaud, Ouafik, L'Houcine, Gaudy-Marqueste, Caroline, Tomasini, Pascale, Charles, Julie, Amini-Adle, Mona, Malissen, Nausicaa

“…Only a fraction of patients with metastatic melanoma derive durable benefit from approved treatments. The clinical impact of personalized medicine strategies…”
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