Search Results - "Malinen, Eirik"

Deep learning-based auto-delineation of gross tumour volumes and involved nodes in PET/CT images of head and neck cancer patients by Moe, Yngve Mardal, Groendahl, Aurora Rosvoll, Tomic, Oliver, Dale, Einar, Malinen, Eirik, Futsaether, Cecilia Marie

“…Purpose Identification and delineation of the gross tumour and malignant nodal volume (GTV) in medical images are vital in radiotherapy. We assessed the…”
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Sharp dose profiles for high precision proton therapy using strongly focused proton beams by Reaz, Fardous, Sjobak, Kyrre Ness, Malinen, Eirik, Edin, Nina Frederike Jeppesen, Adli, Erik

“…The main objective of radiotherapy is to exploit the curative potential of ionizing radiation while inflicting minimal radiation-induced damage to healthy…”
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Proton- compared to X-irradiation leads to more acinar atrophy and greater hyposalivation accompanied by a differential cytokine response by Juvkam, Inga Solgård, Zlygosteva, Olga, Sitarz, Mateusz, Sørensen, Brita Singers, Aass, Hans Christian D., Edin, Nina Jeppesen, Galtung, Hilde Kanli, Søland, Tine Merete, Malinen, Eirik

“…Proton therapy gives less dose to healthy tissue compared to conventional X-ray therapy, but systematic comparisons of normal tissue responses are lacking. The…”
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Author Correction: Combination of proton- or X-irradiation with anti-PDL1 immunotherapy in two murine oral cancers by Rykkelid, Anne Marit, Sinha, Priyanshu Manojkumar, Folefac, Charlemagne Asonganyi, Horsman, Michael R., Sørensen, Brita Singers, Søland, Tine Merete, Schreurs, Olaf Joseph Franciscus, Malinen, Eirik, Edin, Nina Frederike J.

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Classification of Dynamic Contrast Enhanced MR Images of Cervical Cancers Using Texture Analysis and Support Vector Machines by Torheim, Turid, Malinen, Eirik, Kvaal, Knut, Lyng, Heidi, Indahl, Ulf G., Andersen, Erlend K. F., Futsaether, Cecilia M.

“…Dynamic contrast enhanced MRI (DCE-MRI) provides insight into the vascular properties of tissue. Pharmacokinetic models may be fitted to DCE-MRI uptake…”
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Hypoxia-Induced Gene Expression in Chemoradioresistant Cervical Cancer Revealed by Dynamic Contrast-Enhanced MRI by HALLE, Cathinka, ANDERSEN, Erlend, MALINEN, Eirik, LYNG, Heidi, LANDO, Malin, AARNES, Eva-Katrine, HASVOLD, Grete, HOLDEN, Marit, SYLJUASEN, Randi G, SUNDFØR, Kolbein, KRISTENSEN, Gunnar B, HOLM, Ruth

“…Knowledge of the molecular background of functional magnetic resonance (MR) images is required to fully exploit their potential in cancer management. We…”
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Combination of proton- or X-irradiation with anti-PDL1 immunotherapy in two murine oral cancers by Rykkelid, Anne Marit, Sinha, Priyanshu Manojkumar, Folefac, Charlemagne Asonganyi, Horsman, Michael R., Sørensen, Brita Singers, Søland, Tine Merete, Schreurs, Olaf Joseph Franciscus, Malinen, Eirik, Edin, Nina Frederike J.

“…Combining radiation therapy with immunotherapy is a strategy to improve both treatments. The purpose of this study was to compare responses for two syngeneic…”
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Identification and Validation of Reference Genes for RT-qPCR Studies of Hypoxia in Squamous Cervical Cancer Patients by Fjeldbo, Christina S, Aarnes, Eva-Katrine, Malinen, Eirik, Kristensen, Gunnar B, Lyng, Heidi

“…Hypoxia is an adverse factor in cervical cancer, and hypoxia-related gene expression could be a powerful biomarker for identifying the aggressive hypoxic…”
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Strategies for Biologic Image-Guided Dose Escalation: A Review by Søvik, Åste, Ph.D, Malinen, Eirik, Ph.D, Olsen, Dag Rune, Ph.D

“…There is increasing interest in how to incorporate functional and molecular information obtained by noninvasive, three-dimensional tumor imaging into…”
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Low-Dose-Rate Radiation-Induced Secretion of TGF-β3 Together with an Activator in Small Extracellular Vesicles Modifies Low-Dose Hyper-Radiosensitivity through ALK1 Binding by Hanson, Ingunn, Pitman, Kathinka E., Altanerova, Ursula, Altaner, Čestmír, Malinen, Eirik, Edin, Nina F. J.

“…Hyper-radiosensitivity (HRS) is the increased sensitivity to low doses of ionizing radiation observed in most cell lines. We previously demonstrated that HRS…”
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Proton Compared to X-Irradiation Induces Different Protein Profiles in Oral Cancer Cells and Their Derived Extracellular Vesicles by Juvkam, Inga Solgård, Zlygosteva, Olga, Sitarz, Mateusz, Thiede, Bernd, Sørensen, Brita Singers, Malinen, Eirik, Edin, Nina Jeppesen, Søland, Tine Merete, Galtung, Hilde Kanli

“…Extracellular vesicles (EVs) are membrane-bound particles released from cells, and their cargo can alter the function of recipient cells. EVs from X-irradiated…”
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Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer by Fjeldbo, Christina S, Julin, Cathinka H, Lando, Malin, Forsberg, Malin F, Aarnes, Eva-Katrine, Alsner, Jan, Kristensen, Gunnar B, Malinen, Eirik, Lyng, Heidi

“…A 31-gene expression signature reflected in dynamic contrast enhanced (DCE)-MR images and correlated with hypoxia-related aggressiveness in cervical cancer was…”
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Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck by Zlygosteva, Olga, Juvkam, Inga Solgård, Aass, Hans Christian D, Galtung, Hilde K, Søland, Tine M, Malinen, Eirik, Edin, Nina F. J

“…Cytokines are mediators of inflammation that could lead to fibrosis. The aim was to monitor cytokine levels in saliva and serum after locally fractionated…”
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A preclinical model to investigate normal tissue damage following fractionated radiotherapy to the head and neck by Juvkam, Inga Solgård, Zlygosteva, Olga, Arous, Delmon, Galtung, Hilde Kanli, Malinen, Eirik, Søland, Tine Merete, Edin, Nina Jeppesen

“…Radiotherapy (RT) of head and neck (H&N) cancer is known to cause both early- and late-occurring toxicities. To better appraise normal tissue responses and…”
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Radiotherapy-related lymphopenia in patients with advanced non-small cell lung cancer receiving palliative radiotherapy by Abravan, Azadeh, Eide, Hanne Astrid, Helland, Åslaug, Malinen, Eirik

“…•Risk of grade 3 lymphopenia increased with RT dose to the soft tissue and trabecular bone.•High baseline CRP/Albumin was negatively associated with overall…”
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Long-term Cardiac Mortality After Hypofractionated Radiation Therapy in Breast Cancer by Tjessem, Kristin Holm, MD, Johansen, Safora, PhD, Malinen, Eirik, PhD, Reinertsen, Kristin V., MD, PhD, Danielsen, Turi, PhD, Fosså, Sophie D., MD, PhD, Fosså, Alexander, MD, PhD

“…Purpose To explore very-long-term mortality from ischemic heart disease (IHD) after locoregional radiation therapy of breast cancer (BC) in relation to degree…”
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Cluster analysis of dynamic contrast enhanced MRI reveals tumor subregions related to locoregional relapse for cervical cancer patients by Torheim, Turid, Groendahl, Aurora R, Andersen, Erlend K F, Lyng, Heidi, Malinen, Eirik, Kvaal, Knut, Futsaether, Cecilia M

“…Solid tumors are known to be spatially heterogeneous. Detection of treatment-resistant tumor regions can improve clinical outcome, by enabling implementation…”
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Ultra-early changes in vascular parameters from dynamic contrast enhanced MRI of breast cancer xenografts following systemic therapy with doxorubicin and liver X receptor agonist by Pitman, Kathinka E, Bakke, Kine M, Kristian, Alexandr, Malinen, Eirik

“…Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) may be used to depict tumour vascular structure and for therapy response assessment in various…”
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Mapping Bone Marrow Response in the Vertebral Column by Positron Emission Tomography Following Radiotherapy and Erlotinib Therapy of Lung Cancer by Abravan, Azadeh, Eide, Hanne Astrid, Løndalen, Ayca Muftuler, Helland, Åslaug, Malinen, Eirik

“…Purpose To map functional bone marrow (BM) by 2-deoxy-2-[ 18 F]fluoro- d -glucose ([ 18 F]FDG) positron emission tomography (PET) in the vertebral column of…”
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Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of chemoradiotherapy failure independent of intratumour heterogeneity by Fjeldbo, Christina S., Hompland, Tord, Hillestad, Tiril, Aarnes, Eva-Katrine, Günther, Clara-Cecilie, Kristensen, Gunnar B., Malinen, Eirik, Lyng, Heidi

“…Emerging biomarkers from medical imaging or molecular characterization of tumour biopsies open up for combining the two and exploiting their synergy in…”
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