Search Results - "Malikov, Viacheslav"

Localized Phosphorylation of a Kinesin-1 Adaptor by a Capsid-Associated Kinase Regulates HIV-1 Motility and Uncoating by Malikov, Viacheslav, Naghavi, Mojgan H.

“…Although microtubule motors mediate intracellular virus transport, the underlying interactions and control mechanisms remain poorly defined. This is…”
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HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus by Malikov, Viacheslav, da Silva, Eveline Santos, Jovasevic, Vladimir, Bennett, Geoffrey, de Souza Aranha Vieira, Daniel A., Schulte, Bianca, Diaz-Griffero, Felipe, Walsh, Derek, Naghavi, Mojgan H.

“…Intracellular transport of cargos, including many viruses, involves directed movement on microtubules mediated by motor proteins. Although a number of viruses…”
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HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration by Chai, Qingqing, Jovasevic, Vladimir, Malikov, Viacheslav, Sabo, Yosef, Morham, Scott, Walsh, Derek, Naghavi, Mojgan H.

“…While beta-amyloid (Aβ), a classic hallmark of Alzheimer’s disease (AD) and dementia, has long been known to be elevated in the human immunodeficiency virus…”
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FEZ1 Is Recruited to a Conserved Cofactor Site on Capsid to Promote HIV-1 Trafficking by Huang, Pei-Tzu, Summers, Brady James, Xu, Chaoyi, Perilla, Juan R., Malikov, Viacheslav, Naghavi, Mojgan H., Xiong, Yong

“…HIV-1 uses the microtubule network to traffic the viral capsid core toward the nucleus. Viral nuclear trafficking and infectivity require the kinesin-1 adaptor…”
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Author Correction: HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegeneration by Chai, Qingqing, Jovasevic, Vladimir, Malikov, Viacheslav, Sabo, Yosef, Morham, Scott, Walsh, Derek, Naghavi, Mojgan H.

“…The original version of this Article contained an error in the Methods section ‘Viruses and drugs’. The timing for drug treatment of CHME3 4 × 4 or 293T cells…”
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Role of plasma membrane estrogen receptors in mediating the estrogen induction of progesterone receptors in hypothalamic ventromedial neurons by Sá, Susana I., Pereira, Pedro A., Malikov, Viacheslav, Ferreira, Isabel M.P.L.V.O., Madeira, M. Dulce

“…ABSTRACT Progesterone is well known for its role in the modulation of sexual behavior. In the ventromedial nucleus (VMN), a part of the mediobasal hypothalamus…”
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Centering of a radial microtubule array by translocation along microtubules spontaneously nucleated in the cytoplasm by Rodionov, Vladimir, Malikov, Viacheslav, Cytrynbaum, Eric N, Kashina, Anna, Mogilner, Alexander

“…Positioning of a radial array of microtubules (MTs) in the cell centre is crucial for cytoplasmic organization, but the mechanisms of such centering are…”
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Self-Organization of a Radial Microtubule Array by Dynein-Dependent Nucleation of Microtubules by Vorobjev, Ivan, Malikov, Viacheslav, Rodionov, Vladimir

“…Polarized radial arrays of cytoplasmic microtubules (MTs) with minus ends clustered at the cell center define the organization of the cytoplasm through…”
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FEZ1 Plays Dual Roles in Early HIV-1 Infection by Independently Regulating Capsid Transport and Host Interferon-Stimulated Gene Expression by Malikov, Viacheslav, Naghavi, Mojgan H

“…Fasciculation and elongation factor zeta 1 (FEZ1), a multifunctional kinesin-1 adaptor, binds human immunodeficiency virus type 1 (HIV-1) capsids and is…”
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Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport by Delaney, Michael Keegan, Malikov, Viacheslav, Chai, Qingqing, Zhao, Guangyuan, Naghavi, Mojgan H.

“…Diaphanous (Dia)-related formins (DRFs) coordinate cytoskeletal remodeling by controlling actin nucleation and microtubule (MT) stabilization to facilitate…”
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HIV‐1 capsids mimic a microtubule regulator to coordinate early stages of infection by Santos da Silva, Eveline, Shanmugapriya, Shanmugapriya, Malikov, Viacheslav, Gu, Feng, Delaney, M Keegan, Naghavi, Mojgan H

“…While the microtubule end‐binding protein, EB1 facilitates early stages of HIV‐1 infection, how it does so remains unclear. Here, we show that beyond its…”
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FEZ1 phosphorylation regulates HSPA8 localization and interferon-stimulated gene expression by Malikov, Viacheslav, Meade, Nathan, Simons, Lacy M., Hultquist, Judd F., Naghavi, Mojgan H.

“…Fasciculation and elongation protein zeta-1 (FEZ1) is a multifunctional kinesin adaptor involved in processes ranging from neurodegeneration to retrovirus and…”
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Cytoplasmic dynein nucleates microtubules to organize them into radial arrays in vivo by Malikov, Viacheslav, Kashina, Anna, Rodionov, Vladimir

“…Numerous evidence demonstrates that dynein is crucial for organization of microtubules (MTs) into radial arrays, but its exact function in this process is…”
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