Search Results - "Malik, Raleigh"
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938-P: The Relationship between Timing of Initiation on a Glucagon-Like Peptide-1 Receptor Agonist and HbA1c among Patients with Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Onjective: Examine the relationship between timing of initiation on a glucagon-like peptide-1 receptor agonist (GLP-1 RA) and HbA1c. Methods: The IBM…”
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Tirzepatide in Hispanic/Latino Patients With Type 2 Diabetes: A Subgroup Analysis of the SURPASS Program
Published in The journal of clinical endocrinology and metabolism (18-01-2024)“…Abstract Context Efficacy and safety of tirzepatide, a once-weekly glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist,…”
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Effect of dulaglutide 3.0 and 4.5 mg on weight in patients with type 2 diabetes: Exploratory analyses of AWARD‐11
Published in Diabetes, obesity & metabolism (01-10-2021)“…Aim To evaluate the impact of dulaglutide 3.0 and 4.5 mg versus 1.5 mg on body weight in patients with type 2 diabetes (T2D) based on exploratory analyses of…”
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The Relationship Between Timing of Initiation on a Glucagon-like Peptide-1 Receptor Agonist and Glycosylated Hemoglobin Values Among Patients With Type 2 Diabetes
Published in Clinical therapeutics (01-09-2020)“…This study examines the relationship between timing of initiation on a glucagon-like peptide-1 receptor agonist (GLP-1 RA) and glycosylated hemoglobin (HbA1c)…”
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Greater Adherence and Persistence with Injectable Dulaglutide Compared with Injectable Semaglutide at 1-Year Follow-up: Data from US Clinical Practice
Published in Clinical therapeutics (01-04-2022)“…Greater medication adherence and persistence have been associated with improved glycemic control in patients with type 2 diabetes mellitus. This study compared…”
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Maternal and postweaning diet interaction alters hypothalamic gene expression and modulates response to a high-fat diet in male offspring
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-10-2009)“…Epidemiological data and results from animal studies indicate that imbalances in maternal nutrition impact the expression of metabolic disorders in the…”
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Real-World Effectiveness of Dulaglutide in Patients with Type 2 Diabetes Mellitus: A Literature Review
Published in Diabetes therapy (01-07-2020)“…Introduction Randomized controlled trials (RCTs) have demonstrated the efficacy of dulaglutide in adults with type 2 diabetes mellitus (T2DM), but results may…”
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Glycaemic efficacy of an expanded dose range of dulaglutide according to baseline glycated haemoglobin (HbA1c) subgroup: Post hoc analysis of AWARD‐11
Published in Diabetes, obesity & metabolism (01-12-2021)“…The AWARD‐11 trial demonstrated the safety and efficacy of dulaglutide 3.0 and 4.5 mg compared to dulaglutide 1.5 mg in patients with type 2 diabetes…”
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Patient Perceptions of and Preferences Between Characteristics of Injectable Diabetes Treatments
Published in Diabetes therapy (01-09-2021)“…Introduction The administration of medications targeting type 2 diabetes mellitus (T2D) has evolved over time. As injection delivery systems continue to…”
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LHX3 interacts with inhibitor of histone acetyltransferase complex subunits LANP and TAF-1β to modulate pituitary gene regulation
Published in PloS one (04-07-2013)“…LIM-homeodomain 3 (LHX3) is a transcription factor required for mammalian pituitary gland and nervous system development. Human patients and animal models with…”
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The role of DNA methylation in regulation of the murine Lhx3 gene
Published in Gene (25-01-2014)“…LHX3 is a LIM-homeodomain transcription factor with critical roles in pituitary and nervous system development. Mutations in the LHX3 gene are associated with…”
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Enabling social listening for cardiac safety monitoring: Proceedings from a drug information association–cardiac safety research consortium cosponsored think tank
Published in The American heart journal (01-12-2017)“…This white paper provides a summary of the presentations and discussions from a think tank on “Enabling Social Listening for Cardiac Safety Monitoring” trials…”
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Model of pediatric pituitary hormone deficiency separates the endocrine and neural functions of the LHX3 transcription factor in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (04-01-2011)“…The etiology of most pediatric hormone deficiency diseases is poorly understood. Children with combined pituitary hormone deficiency (CPHD) have insufficient…”
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A recessive mutation resulting in a disabling amino acid substitution (T194R) in the LHX3 homeodomain causes combined pituitary hormone deficiency
Published in Hormone research in paediatrics (01-01-2012)“…Recessive mutations in the LHX3 homeodomain transcription factor gene are associated with developmental disorders affecting the pituitary and nervous system…”
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Mechanistic investigation of 9-bromoanthracene photodimers as initiators in atom transfer radical polymerization
Published in Polymer (Guilford) (03-05-2006)“…Mechanistic pathways accounting for the lack of control in polymerizations employing photodimers of 9-bromoanthracene as alkyl halide initiators in atom…”
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Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)
Published in Diabetes care (01-03-2021)“…To compare efficacy and safety of dulaglutide at doses of 3.0 and 4.5 mg versus 1.5 mg in patients with type 2 diabetes inadequately controlled with metformin…”
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Tirzepatide versus Semaglutide 2.4 mg for People with Obesity or Overweight and Type 2 Diabetes
Published in Obesity (Silver Spring, Md.) (01-11-2023)“…Background: Tirzepatide is a glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist under investigation for chronic weight…”
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790-P: The Effect of Tirzepatide vs. Placebo on Changes and Shifts in BMI Category in Adults with Type 2 Diabetes-A Post Hoc Analysis of the SURMOUNT-2 Study
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Tirzepatide (TZP) is a GIP and GLP-1 receptor agonist indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight…”
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Evaluating Health-Related Quality of Life With Tirzepatide in the SURMOUNT-1 Study
Published in Obesity (Silver Spring, Md.) (01-11-2022)“…Background: In SURMOUNT-1, a phase 3, 72-week, randomized, double-blind clinical trial in participants with obesity, tirzepatide, a novel glucose-dependent…”
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Abstract 15280: Does Weight Reduction Drive the Reduction in Blood Pressure in People Living With Obesity Treated With Tirzepatide?: Insights From SURMOUNT-1 Study
Published in Circulation (New York, N.Y.) (07-11-2023)“…Abstract only Background: Tirzepatide (TZP) is a GIP/GLP-1 receptor agonist indicated for the treatment of type 2 diabetes and in development for chronic…”
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