Search Results - "Malik, Neelam"

Curcumin Derivatives Linked to a Reduction of Oxidative Stress in Mental Dysfunctions and Inflammatory Disorders by Dhiman, Priyanka, Malik, Neelam

“…Stress is a critical factor in the etiology of inflammation and neurodegeneration. The risk factor for the majority of psychiatric disorders is oxidative…”
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Quercetin and Related Chromenone Derivatives as Monoamine Oxidase Inhibitors: Targeting Neurological and Mental Disorders by Dhiman, Priyanka, Malik, Neelam, Sobarzo-Sánchez, Eduardo, Uriarte, Eugenio, Khatkar, Anurag

“…Monoamine oxidase inhibitions are considered as important targets for the treatment of depression, anxiety, and neurodegenerative disorders, including…”
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3D-QSAR and in-silico Studies of Natural Products and Related Derivatives as Monoamine Oxidase Inhibitors by Dhiman, Priyanka, Malik, Neelam, Khatkar, Anurag

“…Background: The computational development of human monoamine oxidase (MAO) inhibitors led to advancement in drug design and the treatment of many…”
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In Silico and 3D QSAR Studies of Natural Based Derivatives as Xanthine Oxidase Inhibitors by Malik, Neelam, Dhiman, Priyanka, Khatkar, Anurag

“…A large number of disorders and their symptoms emerge from deficiency or overproduction of specific metabolites has drawn the attention for the discovery of…”
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Natural based piperine derivatives as potent monoamine oxidase inhibitors: an in silico ADMET analysis and molecular docking studies by Dhiman, Priyanka, Malik, Neelam, Khatkar, Anurag

“…Neurodegenerative disorders follow numerous pathological ways concerning overexpression of monoamine oxidase and formation of reactive oxygen species. The…”
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Insights on Quercetin Therapeutic Potential for Neurodegenerative Diseases and its Nano-technological Perspectives by Goyal, Rajat, Mittal, Garima, Khurana, Suman, Malik, Neelam, Kumar, Vivek, Soni, Arti, Chopra, Hitesh, Kamal, Mohammad Amjad

“…The neurodegeneration process begins in conjunction with the aging of the neurons. It manifests in different parts of the brain as Aβ plaques, neurofibrillary…”
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In Silico Design, Synthesis of Hybrid Combinations: Quercetin Based MAO Inhibitors with Antioxidant Potential by Dhiman, Priyanka, Malik, Neelam, Khatkar, Anurag

“…Monoamine oxidase (MAO) is a critical target used for the cure of neuropsychological diseases. A series of quercetin based derivatives was designed,…”
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Computational Analysis and Synthesis of Syringic Acid Derivatives as Xanthine Oxidase Inhibitors by Malik, Neelam, Khatkar, Anurag, Dhiman, Priyanka

“…Xanthine oxidase (XO; EC 1.17.3.2) has been considered as a potent drug target for the cure and management of pathological conditions prevailing due to high…”
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Hybrid caffeic acid derivatives as monoamine oxidases inhibitors: synthesis, radical scavenging activity, molecular docking studies and in silico ADMET analysis by Dhiman, Priyanka, Malik, Neelam, Khatkar, Anurag

“…Background Monoamine oxidase has been implicated in numerous neurological disorders. Although synthetic monoamine oxidase inhibitors (MAOI) have emerged with…”
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Flavonoids and Anthranquinones as Xanthine Oxidase and Monoamine Oxidase Inhibitors: A New Approach Towards Inflammation and Oxidative Stress by Malik, Neelam, Dhiman, Priyanka, Sobarzo-Sanchez, Eduardo, Khatkar, Anurag

“…The development of xanthine oxidase and monoamine oxidase inhibitors led to important breakthroughs in the therapy of oxidative damage, hyperuricemia, gout,…”
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Docking-Related Survey on Natural-Product-Based New Monoamine Oxidase Inhibitors and Their Therapeutic Potential by Dhiman, Priyanka, Malik, Neelam, Khatkar, Anurag

“…This is an exciting period for research on monoamine oxidase and its effects on central nervous system. As the current hitting-one-target, therapeutic strategy…”
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In-silico Design and ADMET Studies of Natural Compounds as Inhibitors of Xanthine Oxidase (XO) Enzyme by Malik, Neelam, Dhiman, Priyanka, Khatkar, Anurag

“…Xanthine oxidase a ubiquitous enzyme has been found to be involved in various pathological disorders including gout, hyperuricemia, inflammation, oxidative…”
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In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors by Malik, Neelam, Dhiman, Priyanka, Khatkar, Anurag

“…Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many…”
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Lead optimization for promising monoamine oxidase inhibitor from eugenol for the treatment of neurological disorder: synthesis and in silico based study by Dhiman, Priyanka, Malik, Neelam, Khatkar, Anurag

“…Natural based inhibitors of monoamine oxidase are promising drug candidates for the treatment of several neurodegenerative and neuropsychological disorders…”
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In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors by Malik, Neelam, Dhiman, Priyanka, Khatkar, Anurag

“…Background Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase…”
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Spondylodiscitis complicated by the ingestion of a button battery: a case report by Sudhakar, Praharaju Janaki, Al Dossary, Jameela, Malik, Neelam

“…A one-and-a-half year old boy who presented with a cough, irritability, and refusal of food was found to have an impacted foreign body in his upper esophagus…”
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Mechanistic approach towards interaction of newly synthesized Hesperidin derivatives against xanthine oxidase by Malik, Neelam, Dhiman, Priyanka, Khatkar, Anurag

“…Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many…”
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Wunderlich syndrome following rupture of a renal angiomyolipoma by Parameswaran, Bimal, Khalid, Mohammed, Malik, Neelam

“…Wunderlich syndrome refers to spontaneous non-traumatic renal bleeding into the subcapsular and/or perirenal space. The appropriate treatment for this…”
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Leiomyoma of bladder by Sudhakar, P. J., Malik, Ashok, Malik, Neelam

“…A case of leiomyoma of urinary bladder, a rare benign tumor, is presented. The patient was a 45-year-old woman with long duration history of dysuria…”
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3D-QSAR andin-silico Studies of Natural Products and Related Derivatives as Monoamine Oxidase Inhibitors by Dhiman, Priyanka, Malik, Neelam, Khatkar, Anurag

“…Background: The computational development of human monoamine oxidase (MAO) inhibitors led to advancement in drug design and the treatment of many…”
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