Search Results - "Malik, Athar N."
-
1
A Unified Framework for Dopamine Signals across Timescales
Published in Cell (10-12-2020)“…Rapid phasic activity of midbrain dopamine neurons is thought to signal reward prediction errors (RPEs), resembling temporal difference errors used in machine…”
Get full text
Journal Article -
2
Genome-wide identification and characterization of functional neuronal activity–dependent enhancers
Published in Nature neuroscience (01-10-2014)“…In this study, the authors describe the subset of activity-regulated enhancers that modulate transcription in cultured neurons and that participate in the…”
Get full text
Journal Article -
3
MEF2D Drives Photoreceptor Development through a Genome-wide Competition for Tissue-Specific Enhancers
Published in Neuron (Cambridge, Mass.) (08-04-2015)“…Organismal development requires the precise coordination of genetic programs to regulate cell fate and function. MEF2 transcription factors (TFs) play…”
Get full text
Journal Article -
4
Evolution of Osteocrin as an activity-regulated factor in the primate brain
Published in Nature (London) (10-11-2016)“…Sensory stimuli drive the maturation and function of the mammalian nervous system in part through the activation of gene expression networks that regulate…”
Get full text
Journal Article -
5
Intraoperative thalamocortical tract monitoring via direct cortical recordings during craniotomy
Published in Clinical neurophysiology (01-07-2021)“…•Direct cortical somatosensory evoked potential (SSEP) recordings are feasible and can reliably monitor thalamocortical input to fronto-parietal regions.•SSEP…”
Get full text
Journal Article -
6
Neurogenic Stress Cardiomyopathy After Aneurysmal Subarachnoid Hemorrhage
Published in World neurosurgery (01-06-2015)“…Background Neurogenic stress cardiomyopathy (NSC) is a known complication of aneurysmal subarachnoid hemorrhage (SAH). Detailed analyses of risk factors for…”
Get full text
Journal Article -
7
Activity-dependent regulation of inhibitory synapse development by Npas4
Published in Nature (30-10-2008)“…Neuronal activity regulates the development and maturation of excitatory and inhibitory synapses in the mammalian brain. Several recent studies have identified…”
Get full text
Journal Article -
8
Tremor Mimicking Ventricular Tachycardia on Telemetry
Published in World neurosurgery (01-03-2021)“…A 79-year-old man with coronary artery disease and tremor-predominant Parkinson's disease underwent a gross total resection of a high-grade glioma and…”
Get full text
Journal Article -
9
Using Whole-Exome Sequencing to Identify Inherited Causes of Autism
Published in Neuron (Cambridge, Mass.) (23-01-2013)“…Despite significant heritability of autism spectrum disorders (ASDs), their extreme genetic heterogeneity has proven challenging for gene discovery. Studies of…”
Get full text
Journal Article -
10
Al-Zahrawi (936–1013 AD): On the Surgical Treatment of Neurological Disorders by the Father of Operative Surgery
Published in World neurosurgery (01-04-2024)“…Medical knowledge during the medieval ages flourished under the influence of great scholars of the Islamic Golden age such as Ibn Sina (Latinized as Avicenna),…”
Get full text
Journal Article -
11
Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation
Published in Biomaterials (01-04-2005)“…The development of biocompatible photopolymerizing polymers for biomedical and tissue engineering applications has the potential to reduce the invasiveness and…”
Get full text
Journal Article -
12
Robot-assisted, CT-guided placement of responsive neurostimulator system with bilateral centromedian thalamus depth electrodes for multifocal intractable epilepsy
Published in Neurosurgical Focus: Video (01-07-2024)“…The responsive neurostimulator system has become increasingly popular in the surgical management of refractory epilepsy, with targeting of various thalamic…”
Get full text
Journal Article -
13
Exploring the Role of the Pulvinar Nucleus of the Thalamus in Occipital Lobe Epilepsy: A Case Report
Published in Curēus (Palo Alto, CA) (18-01-2024)“…Understanding the role of the pulvinar nucleus may be critical for guiding circuit-targeted neurosurgical intervention in some patients. In this report, a…”
Get full text
Journal Article -
14
CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development
Published in Nature genetics (01-11-2012)“…Christopher Walsh and colleagues identify mutations in CHMP1A in human cerebellar hypoplasia and microcephaly. Cells lacking CHMP1A show decreased cell…”
Get full text
Journal Article -
15
Laser ablation for refractory mesial temporal lobe epilepsy
Published in Epileptic disorders (01-06-2022)Get full text
Journal Article -
16
Physician Practice Pattern Variations in Common Clinical Scenarios Within 5 US Metropolitan Areas
Published in JAMA health forum (28-01-2022)“…Importance While variations in quality of care have been described between US regions, physician-level practice pattern variations within regions remain poorly…”
Get full text
Journal Article -
17
A chemical genetic approach reveals distinct EphB signaling mechanisms during brain development
Published in Nature neuroscience (01-12-2012)“…The EphB family of receptor tyrosine kinases can signal bidirectionally and functions in a kinase-dependent and kinase-independent manner. To determine the…”
Get full text
Journal Article -
18
Isolated cerebral mucormycosis of the basal ganglia
Published in Clinical neurology and neurosurgery (01-09-2014)“…Highlights • Isolated cerebral mucormycosis is a rare fungal infection of the nervous system. • Risk factors include IV drug abuse, poorly controlled diabetes,…”
Get full text
Journal Article -
19
Alternating ictal and postictal nystagmus
Published in Neurology. Clinical practice (01-12-2014)Get full text
Journal Article -
20
A Unified Framework for Dopamine Signals Across Timescales
Published in Neurosurgery (01-12-2020)“…INTRODUCTION Aberrant dopamine circuit activity contributes to a variety of neuropsychiatric illnesses including movement disorders, dementia, addiction,…”
Get full text
Journal Article