Search Results - "Malik, Arshi"
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Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and Other Coronaviruses: A Genome-wide Comparative Annotation and Analysis
Published in Molecular and cellular biochemistry (01-05-2021)“…Novel strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) causes mild to severe respiratory illness. The early symptoms may be fever, dry…”
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Garcinol Sensitizes NSCLC Cells to Standard Therapies by Regulating EMT-Modulating miRNAs
Published in International journal of molecular sciences (13-02-2019)“…Garcinol, a dietary factor obtained from , modulates several key cellular signaling pathways as well as the expression of miRNAs. Acquired resistance to…”
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Pomegranate juice anthocyanidins induce cell death in human cancer cells by mobilizing intracellular copper ions and producing reactive oxygen species
Published in Frontiers in oncology (06-09-2022)“…Anthocyanidins are the most abundant polyphenols in pomegranate juice. This class of molecules includes Delphinidin (Del), Cyanidin (Cya), and Pelargonidin…”
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An Update on Genetic Predisposition for Prostate Cancer: Perspectives and Prospects
Published in Cellular and Molecular Biology (28-02-2023)“…Prostate cancer (PC) is a heterogeneous disease that kills a significant number of people all over the world. It is the most common cancer in men, especially…”
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Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer
Published in Proceedings of the National Academy of Sciences - PNAS (11-10-2005)“…Prostate cancer is the most common invasive malignancy and the second leading cause of cancer-related deaths among U.S. males, with a similar trend in many…”
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Pulsatillic acid as a potential inhibitor of protein kinase C-alpha in non-small cell lung cancer
Published in Cellular and Molecular Biology (28-07-2024)“…Non-small cell lung cancer (NSCLC) is a global health concern with a significant impact on morbidity and mortality. Small molecule inhibitors targeting genetic…”
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Delphinidin, an Anthocyanidin in Pigmented Fruits and Vegetables, Protects Human HaCaT Keratinocytes and Mouse Skin Against UVB-Mediated Oxidative Stress and Apoptosis
Published in Journal of investigative dermatology (01-01-2007)“…Solar UV radiation, in particular its UVB component, is the primary cause of many adverse biological effects, the most damaging of which is skin cancer. Here,…”
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Combined Inhibitory Effects of Green Tea Polyphenols and Selective Cyclooxygenase-2 Inhibitors on the Growth of Human Prostate Cancer Cells Both In vitro and In vivo
Published in Clinical cancer research (01-03-2007)“…Purpose: Cyclooxygenase-2 (COX-2) inhibitors hold promise for cancer chemoprevention; however, recent toxicity concerns suggest that new strategies are needed…”
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Influence of ellagic acid on prostate cancer cell proliferation: a caspase-dependent pathway
Published in Asian Pacific journal of tropical medicine (01-07-2011)“…To evaluate the effect of allagic acid treatment on the cell viability of human prostate cancer cells. Ellagic acid (10-100 mol/L) treatment (48 h) of human…”
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Pomegranate Fruit Extract Modulates UV-B–mediated Phosphorylation of Mitogen-activated Protein Kinases and Activation of Nuclear Factor Kappa B in Normal Human Epidermal Keratinocytes
Published in Photochemistry and photobiology (01-01-2005)“…Excessive exposure of solar ultraviolet (UV) radiation, particularly its UV-B component, to humans causes many adverse effects that include erythema,…”
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Cannabinoid Receptor Agonist-induced Apoptosis of Human Prostate Cancer Cells LNCaP Proceeds through Sustained Activation of ERK1/2 Leading to G1 Cell Cycle Arrest
Published in The Journal of biological chemistry (22-12-2006)“…We have recently shown that the expression levels of both cannabinoid receptors CB1 and CB2 are higher in human prostate cancer cells than in normal prostate…”
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3D printing for drug delivery and biomedical applications
Published in Drug discovery today (01-09-2020)“…•3D-Printing has gained attention for its customized manufacturing ability•Highly efficient and effective approach, printing produces low cost medicines•It has…”
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Prostate Cancer Prevention Through Pomegranate Fruit
Published in Cell cycle (Georgetown, Tex.) (15-02-2006)“…Prostate cancer (CaP) is the second leading cause of cancer-related deaths among U.S. males with a similar trend in many Western countries. CaP is an ideal…”
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Receptor-based targeting of engineered nanocarrier against solid tumors: Recent progress and challenges ahead
Published in Biochimica et biophysica acta. General subjects (01-02-2021)“…Background In past few decades, the research on engineered nanocarriers (NCs) has gained significant attention in cancer therapy due to selective delivery of…”
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Nanomedicinal strategies as efficient therapeutic interventions for delivery of cancer vaccines
Published in Seminars in cancer biology (01-02-2021)“…The applications of gene therapy-based treatment of cancers were started almost two decades back as a boon over the chemotherapeutic treatment strategies. Gene…”
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Depression linked to higher antibodies production against estrogenized insulin in type 1 diabetes
Published in International immunopharmacology (01-09-2020)“…•Depression linked to higher antibodies production against estogenized insulin in T1D.•Depression enhance the release of IL-1β and IL-17 in T1D.•Depression…”
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A Dietary Anthocyanidin Delphinidin Induces Apoptosis of Human Prostate Cancer PC3 Cells In vitro and In vivo : Involvement of Nuclear Factor-κB Signaling
Published in Cancer research (Chicago, Ill.) (15-10-2008)“…Abstract Delphinidin, a major anthocyanidin present in many pigmented fruits and vegetables, possesses antioxidant, anti-inflammatory, and antiangiogenic…”
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Estrogenization of insulin by catecholestrogen produced high affinity autoantibodies and altered the normal function of insulin in type 1 diabetes
Published in Life sciences (1973) (01-09-2020)“…Insulin (Ins) covalently modified by catecholestrogens (CEs) was commonly found in diabetic patients who have developed insulin resistance. Estrogenization of…”
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In-silico and in-vitro studies revealed alpha-amyrin as a potent pnhibitor of TLR2 for the therapeutics of bacterial infection and sepsis
Published in Cellular and molecular biology (Noisy-le-Grand, France) (05-06-2024)“…This study employed a multifaceted approach to investigate the inhibitory potential of alpha-amyrin against TLR2, a key player in bacterial infection and…”
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