Search Results - "Malicki, Jarema J."

Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins by Pooranachandran, Niedharsan, Malicki, Jarema J

“…Transport of proteins in the ciliary shaft is driven by microtubule-dependent motors, kinesins. Prior studies suggested that the heterotrimeric ciliary kinesin…”
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STORM imaging reveals the spatial arrangement of transition zone components and IFT particles at the ciliary base in Tetrahymena by Hazime, Khodor S., Zhou, Zhu, Joachimiak, Ewa, Bulgakova, Natalia A., Wloga, Dorota, Malicki, Jarema J.

“…The base of the cilium comprising the transition zone (TZ) and transition fibers (TF) acts as a selecting gate to regulate the intraflagellar transport…”
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Author Correction: STORM imaging reveals the spatial arrangement of transition zone components and IFT particles at the ciliary base in Tetrahymena by Hazime, Khodor S., Zhou, Zhu, Joachimiak, Ewa, Bulgakova, Natalia A., Wloga, Dorota, Malicki, Jarema J.

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The Cilium: Cellular Antenna and Central Processing Unit by Malicki, Jarema J, Johnson, Colin A

“…Cilia mediate an astonishing diversity of processes. Recent advances provide unexpected insights into the regulatory mechanisms of cilium formation, and reveal…”
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Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia by Łysyganicz, Paweł K., Pooranachandran, Niedharsan, Liu, Xinming, Adamson, Kathryn I., Zielonka, Katarzyna, Elworthy, Stone, van Eeden, Fredericus J., Grierson, Andrew J., Malicki, Jarema J.

“…Cilia are evolutionarily highly conserved organelles with important functions in many organs. The extracellular component of the cilium protruding from the…”
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Spatiotemporal features of neurogenesis in the retina of medaka, Oryzias latipes by Kitambi, Satish S., Malicki, Jarema J.

“…The vertebrate retina is very well conserved in evolution. Its structure and functional features are very similar in phyla as different as primates and teleost…”
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The Nuclear Arsenal of Cilia by Johnson, Colin A., Malicki, Jarema J.

“…Several recent studies have revealed that nuclei and cilia share molecular components implicated in DNA damage response, splicing, gene expression, and…”
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Apico-basal Polarity Determinants Encoded by crumbs Genes Affect Ciliary Shaft Protein Composition, IFT Movement Dynamics, and Cilia Length by Hazime, Khodor, Malicki, Jarema J

“…One of the most obvious manifestations of polarity in epithelia is the subdivision of the cell surface by cell junctions into apical and basolateral domains…”
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Identification of additional outer segment targeting signals in zebrafish rod opsin by Fang, Xiaoming, Peden, Andrew A, van Eeden, Fredericus J M, Malicki, Jarema J

“…In vertebrate photoreceptors, opsins are highly concentrated in a morphologically distinct ciliary compartment known as the outer segment (OS). Opsin is…”
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Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor by Leventea, Eleni, Zhu, Zhou, Fang, Xiaoming, Nikolaeva, Yulia, Markham, Eleanor, Hirst, Robert A., van Eeden, Fredericus J. M., Malicki, Jarema J.

“…Here, we report that important regulators of cilia formation and ciliary compartment–directed protein transport function in secretion polarity. Mutations in…”
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The role of endothelial cilia in postembryonic vascular development by Elworthy, Stone, Savage, Aaron M., Wilkinson, Robert N., Malicki, Jarema J., Chico, Timothy J.A.

“…Abstrct Background Cilia are essential for morphogenesis and maintenance of many tissues. Loss‐of‐function of cilia in early Zebrafish development causes a…”
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Forward and reverse genetic approaches to the analysis of eye development in zebrafish by Malicki, Jarema J, Pujic, Zac, Thisse, Christine, Thisse, Bernard, Wei, Xiangyun

“…The zebrafish has been established as a mainstream research system, largely due to the immense success of genetic screens. Over 2000 mutant alleles affecting…”
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The role of crumbs genes in the vertebrate cornea by Beyer, Jill, Zhao, Xinping C, Yee, Richard, Khaliq, Shagufta, McMahon, Timothy T, Ying, Hongyu, Yue, Beatrice Y J T, Malicki, Jarema J

“…To evaluate the role of crumbs genes and related epithelial polarity loci in the vertebrate cornea. The authors used histologic analysis and electron…”
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High-throughput behavioral screening method for detecting auditory response defects in zebrafish by Bang, Pascal I, Yelick, Pamela C, Malicki, Jarema J, Sewell, William F

“…We have developed an automated, high-throughput behavioral screening method for detecting hearing defects in zebrafish. Our assay monitors a rapid escape…”
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Small molecule screen for compounds that affect vascular development in the zebrafish retina by Kitambi, Satish S., McCulloch, Kyle J., Peterson, Randall T., Malicki, Jarema J.

“…Blood vessel formation in the vertebrate eye is a precisely regulated process. In the human retina, both an excess and a deficiency of blood vessels may lead…”
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The zebrafish eye: developmental and genetic analysis by Easter, Jr, Stephen S, Malicki, Jarema J

“…In this review, we have attempted to cover all the major points of zebrafish eye development, and have found that, for the most part, it has much in common…”
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Mutations that affect the survival of selected amacrine cell subpopulations define a new class of genetic defects in the vertebrate retina by Avanesov, Andrei, Dahm, Ralf, Sewell, William F., Malicki, Jarema J.

“…Amacrine neurons are among the most diverse cell classes in the vertebrate retina. To gain insight into mechanisms vital to the production and survival of…”
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Spatio-temporal Features of Neurogenesis in the Retina of Medaka, Oryzias latipes by Kitambi, Satish S., Malicki, Jarema J.

“…The vertebrate retina is very well conserved in evolution. Its structure and functional features are very similar in phyla as different as primates and teleost…”
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Morphology and cell type heterogeneities of the inner ear epithelia in adult and juvenile zebrafish (Danio rerio) by Bang, Pascal I., Sewell, William F., Malicki, Jarema J.

“…Although the zebrafish has become an important model for genetic analysis of the vertebrate auditory system, a comprehensive description of the zebrafish ear…”
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Forward and reverse genetic approaches to the analysis of eye development in zebrafish: Animal models of retinal degeneration: new approaches and applications by MALICKI, Jarema J, PUJIC, Zac, THISSE, Christine, THISSE, Bernard, XIANGYUN WEI

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