Search Results - "Maliakel, Balu"

Influence of a low‐dose supplementation of curcumagalactomannoside complex (CurQfen) in knee osteoarthritis: A randomized, open‐labeled, active‐controlled clinical trial by Thomas, Jestin V., Smina, Thozhuthum Parambil, Khanna, Aman, Kunnumakkara, Ajaikumar B., Maliakel, Balu, Mohanan, Ratheesh, Krishnakumar, Illathu Madhavamenon

“…A 6‐week, randomized, open‐label, active‐controlled clinical trial was conducted to evaluate the influence of a low‐dose curcumagalactomannosides (CGM) (400 mg…”
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Surface-engineered liposomal particles of calcium ascorbate with fenugreek galactomannan enhanced the oral bioavailability of ascorbic acid: a randomized, double-blinded, 3-sequence, crossover study by Joseph, Ashil, Kumar, Dinesh, Balakrishnan, Abhilash, Shanmughan, Prasanth, Maliakel, Balu, IM, Krishnakumar

“…The antioxidant, anti-inflammatory, immunomodulating, anti-thrombotic, and antiviral effects along with its protective effects against respiratory infections…”
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Amelioration of Radiation-Induced Damages in Mice by Curcuminoids: The Role of Bioavailability by Liju, Vijayasteltar B., Thomas, Angel, Sivadasan, Syam Das, Kuttan, Ramadasan, Maliakel, Balu, IM, Krishnakumar

“…The present study investigated the role of free curcuminoids bioavailability on the relative radioprotective efficacy of natural unformulated curcuminoids. A…”
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Sustained-Release Microspheres of Cyclodextrin–Resveratrol Complex Using Fenugreek Galactomannan Hydrogels: A Green Approach to Phytonutrient Delivery by Kannamangalam Vijayan, Umesh, Krishna, Aswadh, Shanmughan, Prasanth, Maliakel, Balu, Illathu Madhavamenon, Krishnakumar

“…Food matrices are becoming increasingly complex with the impregnation of phytonutrients with health-beneficial pharmacological effects. Herein, we report the…”
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Clove Bud Polyphenols Alleviate Alterations in Inflammation and Oxidative Stress Markers Associated with Binge Drinking: A Randomized Double-Blinded Placebo-Controlled Crossover Study by Mammen, Renny Reji, Natinga Mulakal, Johannah, Mohanan, Ratheesh, Maliakel, Balu, Illathu Madhavamenon, Krishnakumar

“…Acetaldehyde, the major cytotoxin formed by the metabolism of alcohol, is responsible for liver injury, extracellular matrix alterations, inflammation, and…”
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Safety assessment of a highly bioavailable curcumin-galactomannoside complex (CurQfen) in healthy volunteers, with a special reference to the recent hepatotoxic reports of curcumin supplements: A 90-days prospective study by Pancholi, Vaibhavi, Smina, Thozhuthum Parambil, Kunnumakkara, Ajaikumar B., Maliakel, Balu, Krishnakumar, Illathu Madhavamenon

“…[Display omitted] •CGM did not cause adverse effects or significant variations in clinical parameters.•Liver and renal function markers were in normal range…”
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Enhanced bioavailability and pharmacokinetics of a novel hybrid-hydrogel formulation of fisetin orally administered in healthy individuals: a randomised double-blinded comparative crossover study by Krishnakumar, Illathu Madhavamenon, Jaja-Chimedza, Asha, Joseph, Ashil, Balakrishnan, Abhilash, Maliakel, Balu, Swick, Andrew

“…Fisetin, a polyphenol found in several fruits and vegetables, has shown potential health benefits in many pre-clinical studies for neuroprotection,…”
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Enhanced Bioavailability and Pharmacokinetics of a Natural Self-Emulsifying Reversible Hybrid-Hydrogel System of Quercetin: A Randomized Double-Blinded Comparative Crossover Study by Joseph, Ashil, Shanmughan, Prasanth, Balakrishnan, Abhilash, Maliakel, Balu, M, Krishnakumar I

“…Despite the vast array of health beneficial pharmacological effects, the bioavailability of the dietary flavonoid quercetin was found to be poor due to…”
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A Novel Curcumin-Galactomannoside Complex Delivery System Improves Hepatic Function Markers in Chronic Alcoholics: A Double-Blinded, randomized, Placebo-Controlled Study by Maliakel, Balu P., Mulakal, Johannah N., Nair, Saritha S., Thomas, Justin V., Krishnareddy, Naveen T., Krishnakumar, I. M.

“…Considering the recent interest in free (unconjugated) curcuminoids delivery, the present study investigated the efficacy of a novel food-grade…”
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Micelle/Hydrogel Composite as a “Natural Self-Emulsifying Reversible Hybrid Hydrogel (N’SERH)” Enhances the Oral Bioavailability of Free (Unconjugated) Resveratrol by Joseph, Ashil, Balakrishnan, Abhilash, Shanmughan, Prasanth, Maliakel, Balu, Illathu Madhavamenon, Krishnakumar

“…The poor oral bioavailability, rapid biotransformation to less active metabolites, and fast elimination from systemic circulation have been identified as the…”
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Safety and influence of a novel extract of fenugreek on healthy young women: a randomized, double-blinded, placebo-controlled study by Khanna, Aman, Thomas, Jestin, John, Febi, Maliakel, Balu, Krishnakumar, I. M.

“…Background Fenugreek ( Trigonella foenum-graecum ) seed is a popular kitchen spice and medicinal herb with wide applications in Indian folklore. Earlier…”
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A green approach for the sustained-intestinal delivery of red chili (Capsicum annum L) extracted capsaicinoids with enhanced bioavailability by Joseph, Ashil, Maliakkal Balakrishnan, Abhilash, Natinga Mulakal, Johannah, Das Sivadasan, Syam, Mohan, Ratheesh, Maliakel, Balu, Illathu Madhavamenon, Krishnakumar

“…[Display omitted] •Intestinal delivery of red chili extracted capsaicinoids with enhanced bioavailability.•Pungency masked food-grade beadlets employing…”
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Safety and Efficacy of Ferula asafoetida in Functional Dyspepsia: A Randomized, Double-Blinded, Placebo-Controlled Study by Maliakel, Balu, Syam, Das S., Thomas, Jestin, Mala, K. N., Krishnakumar, I. M.

“…Despite the availability of various synthetic drugs for the treatment of functional dyspepsia (FD), the side effects and their cost have always created a great…”
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Safety assessment of a standardized polyphenolic extract of clove buds: Subchronic toxicity and mutagenicity studies by Vijayasteltar, Liju, Nair, Gopakumar Gopinathan, Maliakel, Balu, Kuttan, Ramadasan, I M, Krishnakumar

“…Despite the various reports on the toxicity of clove oil and its major component eugenol, systematic evaluations on the safety of polyphenolic extracts of…”
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An enhanced bioavailable formulation of curcumin using fenugreek-derived soluble dietary fibre by IM, Krishnakumar, Ravi, Abhilash, Kumar, Dinesh, Kuttan, Ramadasan, Maliakel, Balu

“…Poor intestinal absorption has been regarded as a major limiting factor for the therapeutic use of curcumin, the primary active constituent of turmeric…”
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Two-Stage Supramolecular Self-Assembly-Directed Collagen-Peptide-Decorated Liposomal Complexes of Curcumin Microspheres with Enhanced Solubility and Bioavailability by Louis, Maria Jose, Balakrishnan, Abhilash, Joseph, Ashil, Shanmughan, Prasanth, Maliakel, Balu, Illathu Madhavamenon, Krishnakumar

“…Green formulations of phytonutrients with enhanced solubility and bioavailability are of great significance in nutrition therapy. In the present contribution,…”
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Enhanced absorption of curcuminoids and 3-Acetyl-11-keto-β-boswellic acid from fenugreek galactomannan hydrogel beadlets: A natural approach to the co-delivery of lipophilic phytonutrients by Abhilash, Maliakkal Balakrishnan, Kumar, Dinesh, Deepti, Ayswaria, Nair, Aswathi, Greet, Vanheule, An-Katrien, Vynckier, Mieke, Van Den Driessche, Das Sivadasan, Syam, Maliakel, Balu, Chakrapani PS, Baby, Illathu Madhavamenon, Krishnakumar

“…Simultaneous oral delivery of bioactive molecules with enhanced bioavailability is of great significance, especially when delivered from single beadlets. Here,…”
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Dietary addition of a standardized extract of turmeric (TurmaFEED TM ) improves growth performance and carcass quality of broilers by Nm, Johannah, Joseph, Ashil, Maliakel, Balu, Im, Krishnakumar

“…Indiscriminate use of antibiotics in livestock and poultry farming has caused emergence of new pathogenic strains. The situation has warrented the development…”
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Corrigendum to “A Novel Curcumin-Galactomannoside Complex Delivery System Improves Hepatic Function Markers in Chronic Alcoholics: A Double-Blinded, randomized, Placebo-Controlled Study” by Krishnakumar, I. M., Mulakal, Johannah N., Nair, Saritha S., Thomas, Justin V., Krishnareddy, Naveen T., Maliakel, Balu P.

“…In the article titled “A Novel Curcumin-Galactomannoside Complex Delivery System Improves Hepatic Function Markers in Chronic Alcoholics: A Double-Blinded,…”
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Enhanced anti-diabetic activity of polyphenol-rich de-coumarinated extracts of Cinnamomum cassia by Kumar, Krishna, Issac, Abin, Ninan, Eapen, Kuttan, Ramadassan, Maliakel, Balu

“…•Preparation of de-coumarinated water soluble polyphenol extracts of Cinnamomum cassia.•Investigated the safety and effect of polyphenols on STZ-induced…”
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