Search Results - "Malheiros, Denise"

Pulmonary and systemic involvement in COVID‐19 patients assessed with ultrasound‐guided minimally invasive autopsy by Duarte‐Neto, Amaro N, Monteiro, Renata A A, Silva, Luiz F F, Malheiros, Denise M A C, Oliveira, Ellen P, Theodoro‐Filho, Jair, Pinho, João R R, Gomes‐Gouvêa, Michele S, Salles, Ana P M, Oliveira, Ilka R S, Mauad, Thais, Saldiva, Paulo H N, Dolhnikoff, Marisa

“…Aims Brazil ranks high in the number of coronavirus disease 19 (COVID‐19) cases and the COVID‐19 mortality rate. In this context, autopsies are important to…”
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Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection by Mauad, Thais, Hajjar, Ludhmila A, Callegari, Giovanna D, da Silva, Luiz F. F, Schout, Denise, Galas, Filomena R. B. G, Alves, Venancio A. F, Malheiros, Denise M. A. C, Auler, Jose O. C., Jr, Ferreira, Aurea F, Borsato, Marcela R. L, Bezerra, Stephania M, Gutierrez, Paulo S, Caldini, Elia T. E. G, Pasqualucci, Carlos A, Dolhnikoff, Marisa, Saldiva, Paulo H. N

“…There are no reports of the systemic human pathology of the novel swine H1N1 influenza (S-OIV) infection. The autopsy findings of 21 Brazilian patients with…”
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Mesenchymal Stem Cells Attenuate Renal Fibrosis Through Immune Modulation and Remodeling Properties in a Rat Remnant Kidney Model by Semedo, Patricia, Correa‐Costa, Matheus, Antonio Cenedeze, Marcos, Maria Avancini Costa Malheiros, Denise, Antonia dos Reis, Marlene, Shimizu, Maria Heloisa, Seguro, Antonio Carlos, Pacheco‐Silva, Alvaro, Saraiva Ĉamara, Niels Olsen

“…Mesenchymal stem cells (MSCs) have regenerative properties in acute kidney injury, but their role in chronic kidney diseases is still unknown. More…”
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Antifibrotic Effect of Tamoxifen in a Model of Progressive Renal Disease by DELLE, Humberto, ROCHA, José Roberto C, CAVAGLIERI, Rita C, MAURO VIEIRA, José, MALHEIROS, Denise M. A. C, NORONHA, Irene L

“…Tamoxifen, a selective estrogen receptor modulator, has antifibrotic properties; however, whether it can attenuate renal fibrosis is unknown. In this study, we…”
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Evidences of histologic thrombotic microangiopathy and the impact in renal outcomes of patients with IgA nephropathy by Neves, Precil Diego Miranda de Menezes, Souza, Rafael A, Torres, Fábio M, Reis, Fábio A, Pinheiro, Rafaela B, Dias, Cristiane B, Yu, Luis, Woronik, Viktoria, Furukawa, Luzia S, Cavalcante, Lívia B, de Almeida Araújo, Stanley, Wanderley, David Campos, Malheiros, Denise M, Jorge, Lectícia B

“…IgA nephropathy (IgAN) is the most common primary glomerulopathy worldwide. According to the Oxford Classification, changes in the kidney vascular compartment…”
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Pathogenic role of angiotensin II and the NF-κB system in a model of malignant hypertensive nephrosclerosis by Ávila, Victor F, Foresto-Neto, Orestes, Arias, Simone C A, Faustino, Viviane D, Malheiros, Denise M A C, Camara, Niels O S, Zatz, Roberto, Fujihara, Clarice K

“…We previously reported that rats treated with an NF-κB inhibitor, pyrrolidine dithiocarbamate (PDTC), during lactation developed hypertension in adult life,…”
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TLR2 and TLR4 play opposite role in autophagy associated with cisplatin-induced acute kidney injury by Andrade-Silva, Magaiver, Cenedeze, Marcos Antonio, Perandini, Luiz Augusto, Felizardo, Raphael José Ferreira, Watanabe, Ingrid Kazue Mizuno, Agudelo, Juan Sebastian Henao, Castoldi, Angela, Gonçalves, Giselle Martins, Origassa, Clarice Silvia Taemi, Semedo, Patricia, Hiyane, Meire Ioshie, Foresto-Neto, Orestes, Malheiros, Denise Maria Avancini Costa, Reis, Marlene Antonia, Fujihara, Clarice Kazue, Zatz, Roberto, Pacheco-Silva, Alvaro, Câmara, Niels Olsen Saraiva, de Almeida, Danilo Candido

“…Acute kidney injury (AKI) is considered an inflammatory disease in which toll-like receptors (TLRs) signaling pathways play an important role. The activation…”
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Klotho deficiency aggravates sepsis-related multiple organ dysfunction by Jorge, Lectícia B, Coelho, Fernanda O, Sanches, Talita R, Malheiros, Denise M A C, Ezaquiel de Souza, Leandro, Dos Santos, Fernando, de Sá Lima, Larissa, Scavone, Cristóforo, Irigoyen, Maria, Kuro-O, Makoto, Andrade, Lucia

“…Sepsis-induced organ failure is characterized by a massive inflammatory response and oxidative stress. Acute kidney injury (AKI) occurs in approximately half…”
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Mesenchymal Stromal Cells Induce Podocyte Protection in the Puromycin Injury Model by Ornellas, Felipe Mateus, Ramalho, Rodrigo J., Fanelli, Camilla, Garnica, Margoth Ramos, Malheiros, Denise M. A. C., Martini, Sabrina Vargas, Morales, Marcelo Marcos, Noronha, Irene L.

“…Podocytes are specialized cells with a limited capacity for cell division that do not regenerate in response to injury and loss. Insults that compromise the…”
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Schistosoma mansoni infection as a trigger to collapsing glomerulopathy in a patient with high-risk APOL1 genotype by Neves, Precil D, Bridi, Ramaiane A, Ramalho, Janaína A, Jorge, Lectícia B, Watanabe, Elieser H, Watanabe, Andreia, Yu, Luis, Woronik, Viktoria, Pinheiro, Rafaela B, Testagrossa, Leonardo A, Cavalcante, Lívia B, Malheiros, Denise M, Dias, Cristiane B, Onuchic, Luiz F

“…Schistosoma mansoni schistosomiasis (SM) remains a public health problem in Brazil. Renal involvement is classically manifested as a glomerulopathy, most often…”
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Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model by Fanelli, Camilla, Arias, Simone C. A., Machado, Flavia G., Okuma, Jessica K., Malheiros, Denise M. A. C., Azevedo, Hatylas, Moreira-Filho, Carlos A., Camara, Niels O. S., Fujihara, Clarice K., Zatz, Roberto

“…The mechanisms triggering renal inflammation in chronic kidney disease (CKD) are unclear. We performed a detailed analysis of the time course of innate and…”
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Determination of Anti-Phospholipase A2 and Anti-Thrombospondin Type 1 Domain-Containing Protein 7A in Latin Patients with Membranous Nephropathy by Battaini, Ligia C, Ranzani, Otavio T, Marçal, Lia J, Antonangelo, Leila, Jorge, Lecticia B, Bitencourt, Cristiane D, Woronik, Victoria, Malheiros, Denise M A, Yu, Luis

“…Primary membranous nephropathy (MN) is caused by antibodies against podocyte antigens, especially the type M receptor of phospholipase A2 (PLA2R) and…”
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NLRP3 inflammasome inhibition ameliorates tubulointerstitial injury in the remnant kidney model by Foresto-Neto, Orestes, Ávila, Victor Ferreira, Arias, Simone Costa Alarcon, Zambom, Fernanda Florencia Fregnan, Rempel, Lisienny Campoli Tono, Faustino, Viviane Dias, Machado, Flavia Gomes, Malheiros, Denise Maria Avancini Costa, Abensur, Hugo, Camara, Niels Olsen Saraiva, Zatz, Roberto, Fujihara, Clarice Kazue

“…Recent studies suggest that NLRP3 inflammasome activation is involved in the pathogenesis of chronic kidney disease (CKD). Allopurinol (ALLO) inhibits xanthine…”
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Activation of platelet-activating factor receptor exacerbates renal inflammation and promotes fibrosis by Correa-Costa, Matheus, Andrade-Oliveira, Vinicius, Braga, Tarcio T, Castoldi, Angela, Aguiar, Cristhiane F, Origassa, Clarice ST, Rodas, Andrea CD, Hiyane, Meire I, Malheiros, Denise MAC, Rios, Francisco JO, Jancar, Sonia, Câmara, Niels OS

“…Platelet-activating factor (PAF) is a lipid mediator with important pro-inflammatory effects, being synthesized by several cell types including kidney cells…”
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Kinin B1 receptor deficiency attenuates cisplatin-induced acute kidney injury by modulating immune cell migration by Estrela, Gabriel R., Wasinski, Frederick, Almeida, Danilo C., Amano, Mariane T., Castoldi, Angela, Dias, Carolina C., Malheiros, Denise M. A. C., Almeida, Sandro S., Paredes-Gamero, Edgar J., Pesquero, João B., Barros, Carlos C., Câmara, Niels O. S., Araújo, Ronaldo C.

“…Cisplatin is a chemotherapeutic agent that causes severe renal dysfunction. The kinin B1 receptor has been associated with the migration of immune cells to…”
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Pathogenic role of innate immunity in a model of chronic NO inhibition associated with salt overload by Zambom, Fernanda Florencia Fregnan, Oliveira, Karin Carneiro, Foresto-Neto, Orestes, Faustino, Viviane Dias, Ávila, Victor Ferreira, Albino, Amanda Helen, Arias, Simone Costa Alarcon, Volpini, Rildo Aparecido, Malheiros, Denise Maria Avancini Costa, Saraiva Camara, Niels Olsen, Zatz, Roberto, Fujihara, Clarice Kazue

“…Nitric oxide inhibition with -nitro-l-arginine methyl ester (l-NAME), along with salt overload, leads to hypertension, albuminuria, glomerulosclerosis,…”
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Regression of glomerular injury by losartan in experimental diabetic nephropathy by Teles, Flávio, Machado, Flávia G., Ventura, Bianca H., Malheiros, Denise M.A.C., Fujihara, Clarice K., Silva, Luís F.F., Zatz, Roberto

“…Many features of chronic kidney disease may be reversed, but it is unclear whether advanced lesions, such as adhesions of sclerotic glomerular tufts to…”
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Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury by Rodrigues, Camila Eleuterio, Capcha, José Manuel Condor, de Bragança, Ana Carolina, Sanches, Talita Rojas, Gouveia, Priscila Queiroz, de Oliveira, Patrícia Aparecida Ferreira, Malheiros, Denise Maria Avancini Costa, Volpini, Rildo Aparecido, Santinho, Mirela Aparecida Rodrigues, Santana, Bárbara Amélia Aparecida, Calado, Rodrigo do Tocantins, Noronha, Irene de Lourdes, Andrade, Lúcia

“…Mesenchymal stromal cells (MSCs) represent an option for the treatment of acute kidney injury (AKI). It is known that young stem cells are better than are aged…”
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A life-threatening case of TAFRO syndrome with dramatic response to tocilizumab, rituximab, and pulse steroids: The first case report in Latin America by José, Fabio Freire, Kerbauy, Lucila Nassif, Perini, Guilherme Fleury, Blumenschein, Danielle Isadora, Pasqualin, Denise da Cunha, Malheiros, Denise Maria Avancini Costa, Campos Neto, Guilherme de Carvalho, de Souza Santos, Fabio Pires, Piovesan, Ronaldo, Hamerschlak, Nelson

“…This is the report of the first case of TAFRO syndrome (Thrombocytopenia, Anasarca, myelofibrosis, Renal dysfunction, Organomegaly) in Latin America. The…”
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Apolipoprotein A-I mimetic peptide 4F attenuates kidney injury, heart injury, and endothelial dysfunction in sepsis by Moreira, Roberto S, Irigoyen, Maria, Sanches, Talita R, Volpini, Rildo A, Camara, Niels O S, Malheiros, Denise M, Shimizu, Maria H M, Seguro, Antonio C, Andrade, Lucia

“…Kidney injury, heart injury, and cytokine-induced vascular hyperpermeability are associated with high rates of morbidity and mortality in sepsis. Although the…”
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