Urinary steroid profiling by gas chromatography mass spectrometry: Early features of malignancy in patients with adrenal incidentalomas

•Urinary steroids are studied with GC–MS after surgery in patients with adrenocortical adenomas.•Patients with ACA + malignant potential had a sensitivity and specificity of major biomarkers of ACC.•Obtained data supports the hypothesis of a possible transformation of ACA into ACC.

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Bibliographic Details
Published in:	Steroids Vol. 135; pp. 31 - 35
Main Authors:	Shafigullina, Z.R., Velikanova, L.I., Vorokhobina, N.V., Shustov, S.B., Lisitsin, A.A., Malevanaia, E.V., Buinova, M.O., Bessonova, E.A., Kirsanov, D.O.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-07-2018
Subjects:	Adrenal Gland Neoplasms - urine Adult Biomarkers, Tumor - urine Case-Control Studies Female Gas Chromatography-Mass Spectrometry Humans Male Middle Aged Steroids - urine Time Factors
Online Access:	Get full text
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Description
Summary:	•Urinary steroids are studied with GC–MS after surgery in patients with adrenocortical adenomas.•Patients with ACA + malignant potential had a sensitivity and specificity of major biomarkers of ACC.•Obtained data supports the hypothesis of a possible transformation of ACA into ACC.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0039-128X 1878-5867
DOI:	10.1016/j.steroids.2018.04.006