Search Results - "Maldonado, Perla D"

Canonical and non-canonical mechanisms of Nrf2 activation by Silva-Islas, Carlos Alfredo, Maldonado, Perla D.

“…[Display omitted] Nuclear Factor Erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates the expression of genes involved in the…”
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Experimental Pulmonary Tuberculosis in the Absence of Detectable Brain Infection Induces Neuroinflammation and Behavioural Abnormalities in Male BALB/c Mice by Lara-Espinosa, Jacqueline V, Santana-Martínez, Ricardo A, Maldonado, Perla D, Zetter, Mario, Becerril-Villanueva, Enrique, Pérez-Sánchez, Gilberto, Pavón, Lenin, Mata-Espinosa, Dulce, Barrios-Payán, Jorge, López-Torres, Manuel O, Marquina-Castillo, Brenda, Hernández-Pando, Rogelio

“…Tuberculosis (TB) is a chronic infectious disease in which prolonged, non-resolutive inflammation of the lung may lead to metabolic and neuroendocrine…”
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Effect of Curcumin in Experimental Pulmonary Tuberculosis: Antimycobacterial Activity in the Lungs and Anti-Inflammatory Effect in the Brain by Lara-Espinosa, Jacqueline V, Arce-Aceves, María Fernanda, López-Torres, Manuel O, Lozano-Ordaz, Vasti, Mata-Espinosa, Dulce, Barrios-Payán, Jorge, Silva-Islas, Carlos Alfredo, Maldonado, Perla D, Marquina-Castillo, Brenda, Hernández-Pando, Rogelio

“…Tuberculosis (TB) is one of the ten leading causes of death worldwide. Patients with TB have been observed to suffer from depression and anxiety linked to…”
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Apocynin protects against neurological damage induced by quinolinic acid by an increase in glutathione synthesis and Nrf2 levels by Cruz-Álvarez, Silvia, Santana-Martínez, Ricardo, Avila-Chávez, Euclides, Barrera-Oviedo, Diana, Hernández-Pando, Rogelio, Pedraza-Chaverri, José, Maldonado, Perla D

“…Highlights • APO treatment decreased the QUIN-induced histological damage. • APO treatment increased GSH levels and the activity of GSH metabolism-related…”
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Antioxidant and Anti-Inflammatory Effects of Garlic in Ischemic Stroke: Proposal of a New Mechanism of Protection through Regulation of Neuroplasticity by Bautista-Perez, Sandra Monserrat, Silva-Islas, Carlos Alfredo, Sandoval-Marquez, Oscar Uriel, Toledo-Toledo, Jesús, Bello-Martínez, José Manuel, Barrera-Oviedo, Diana, Maldonado, Perla D

“…Stroke represents one of the main causes of death and disability in the world; despite this, pharmacological therapies against stroke remain insufficient…”
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Antitumor Effects of Natural Compounds Derived from Allium sativum on Neuroblastoma: An Overview by Patiño-Morales, Carlos César, Jaime-Cruz, Ricardo, Sánchez-Gómez, Concepción, Corona, Juan Carlos, Hernández-Cruz, Estefani Yaquelin, Kalinova-Jelezova, Ivia, Pedraza-Chaverri, José, Maldonado, Perla D, Silva-Islas, Carlos Alfredo, Salazar-García, Marcela

“…Garlic ( ) has been used in alternative medicine to treat several diseases, such as cardiovascular and neurodegenerative diseases, cancer, and hepatic…”
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The Therapeutic Effect of Curcumin in Quinolinic Acid-Induced Neurotoxicity in Rats is Associated with BDNF, ERK1/2, Nrf2, and Antioxidant Enzymes by Santana-Martínez, Ricardo A, Silva-Islas, Carlos A, Fernández-Orihuela, Yessica Y, Barrera-Oviedo, Diana, Pedraza-Chaverri, José, Hernández-Pando, Rogelio, Maldonado, Perla D

“…In the present study we investigated the participation of brain-derived neurotropic factor (BDNF) on the activation of the mitogen activated protein kinase…”
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Diallyl Trisulfide Protects Rat Brain Tissue against the Damage Induced by Ischemia-Reperfusion through the Nrf2 Pathway by Silva-Islas, Carlos A., Chánez-Cárdenas, María E., Barrera-Oviedo, Diana, Ortiz-Plata, Alma, Pedraza-Chaverri, José, Maldonado, Perla D.

“…Stroke is a public health problem due to its high mortality and disability rates; despite these, the pharmacological treatments are limited. Oxidative stress…”
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S-allyl Cysteine, a Garlic Compound, Produces an Antidepressant-Like Effect and Exhibits Antioxidant Properties in Mice by Ruiz-Sanchez, Elizabeth, Pedraza-Chaverri, Jose, Medina-Campos, Omar N, Maldonado, Perla D, Rojas, Patricia

“…Depression is a psychiatric disorder, and oxidative stress is a significant mechanism of damage in this mood disorder. It is characterized by an enhancement of…”
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Antioxidant Activity of A-Type Proanthocyanidins from Geranium niveum (Geraniaceae) by Maldonado, Perla D, Rivero-Cruz, Isabel, Mata, Rachel, Pedraza-Chaverrí, José

“…Geranium niveum S. Watson (Geraniaceae) is a medicinal herb widely used by the Tarahumara Indians of Mexico. This species is rich in proanthocyanidins and…”
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Aged garlic extract and S-allylcysteine prevent apoptotic cell death in a chemical hypoxia model by Orozco-Ibarra, Marisol, Muñoz-Sánchez, Jorge, Zavala-Medina, Martín E, Pineda, Benjamín, Magaña-Maldonado, Roxana, Vázquez-Contreras, Edgar, Maldonado, Perla D, Pedraza-Chaverri, José, Chánez-Cárdenas, María Elena

“…Aged garlic extract (AGE) and its main constituent S-allylcysteine (SAC) are natural antioxidants with protective effects against cerebral ischemia or cancer,…”
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S-Allylcysteine prevents the rat from 3-nitropropionic acid-induced hyperactivity, early markers of oxidative stress and mitochondrial dysfunction by Herrera-Mundo, María N., Silva-Adaya, Daniela, Maldonado, Perla D., Galván-Arzate, Sonia, Andrés-Martínez, Leticia, Pérez-De La Cruz, Verónica, Pedraza-Chaverrí, José, Santamaría, Abel

“…We investigated the effects of S-allylcysteine (SAC) on early behavioral alterations, striatal changes in superoxide dismutase (SOD) activity, lipid…”
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Protective Effect of Tert-Butylhydroquinone on the Quinolinic-Acid-Induced Toxicity in Rat Striatal Slices: Role of the Nrf2-Antioxidant Response Element Pathway by Tasset, Inmaculada, Pérez-De La Cruz, Verónica, Elinos-Calderón, Diana, Carrillo-Mora, Paul, González-Herrera, Irma Gabriela, Luna-López, Armando, Konigsberg, Mina, Pedraza-Chaverrí, José, Maldonado, Perla D., Ali, Syed F., Túnez, Isaac, Santamaría, Abel

“…Tert-butylhydroquinone (tBHQ) is a xenobiotic with reported antioxidant properties. tBHQ has been shown to induce nuclear translocation of the transcription…”
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Diazepam Blocks Striatal Lipid Peroxidation and Improves Stereotyped Activity in a Rat Model of Acute Stress by Méndez‐Cuesta, Luis A., Márquez‐Valadez, Berenice, Pérez‐De La Cruz, Verónica, Escobar‐Briones, Carolina, Galván‐Arzate, Sonia, Alvarez‐Ruiz, Yarummy, Maldonado, Perla D., Santana, Ricardo A., Santamaría, Abel, Carrillo‐Mora, Paul

“…:  In this work, the effect of a single dose of diazepam was tested on different markers of oxidative damage in the striatum of rats in an acute model of…”
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The Antioxidant Mechanisms Underlying the Aged Garlic Extract- and S-Allylcysteine-Induced Protection by Colín-González, Ana L., Santana, Ricardo A., Silva-Islas, Carlos A., Chánez-Cárdenas, Maria E., Santamaría, Abel, Maldonado, Perla D.

“…Aged garlic extract (AGE) is an odorless garlic preparation containing S-allylcysteine (SAC) as its most abundant compound. A large number of studies have…”
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Antinociceptive effect of garlic, garlic preparations and derivative compounds by Hernández‐Cruz, Estefani Yaquelin, Silva‐Islas, Carlos Alfredo, Maldonado, Perla D., Pedraza‐Chaverri, José, Carballo‐Villalobos, Azucena Ibeth

“…Background and objective The antinociceptive effects of garlic have shown promise in treating different chronic diseases in humans, such as knee…”
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Quinolinic Acid Induces Alterations in Neuronal Subcellular Compartments, Blocks Autophagy Flux and Activates Necroptosis and Apoptosis in Rat Striatum by Silva-Islas, Carlos Alfredo, Santana-Martínez, Ricardo Alberto, León-Contreras, Juan Carlos, Barrera-Oviedo, Diana, Pedraza-Chaverri, Jose, Hernández-Pando, Rogelio, Maldonado, Perla D.

“…Quinolinic acid (QUIN) is an agonist of N -methyl- d -aspartate receptor (NMDAr) used to study the underlying mechanism of excitotoxicity in animal models…”
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Sustained Activation of JNK Induced by Quinolinic Acid Alters the BDNF/TrkB Axis in the Rat Striatum by Santana-Martínez, Ricardo A., León-Contreras, Juan Carlos, Barrera-Oviedo, Diana, Pedraza-Chaverri, José, Hernández-Pando, Rogelio, Maldonado, Perla D.

“…•QUIN increases JNK activation at 7 days post-injury.•JNK activation is sustained in mitochondria and endoplasmic reticulum.•Inactivation of JNK prevents the…”
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Time course study of oxidative and nitrosative stress and antioxidant enzymes in K2Cr2O7-induced nephrotoxicity by Pedraza-Chaverrí, José, Barrera, Diana, Medina-Campos, Omar N, Carvajal, Raymundo C, Hernández-Pando, Rogelio, Macías-Ruvalcaba, Norma A, Maldonado, Perla D, Salcedo, Marcos I, Tapia, Edilia, Saldívar, Liliana, Castilla, María E, Ibarra-Rubio, María E

“…Potassium dichromate (K2Cr2O7)-induced nephrotoxicity is associated with oxidative and nitrosative stress. In this study we investigated the relation between…”
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Acute expression of the transcription factor Nrf2 after treatment with quinolinic acid is not induced by oxidative stress in the rat striatum by Silva-Islas, Carlos Alfredo, Chánez-Cárdenas, María Elena, Barrera-Oviedo, Diana, Ibarra-Rubio, María Elena, Maldonado, Perla D.

“…•Quinolinic acid increases the transcriptional activity of Nrf2 at 30 min.•Quinolinic acid does not induce ROS production at 30 min.•Nrf2 activation at 30 min…”
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