Search Results - "Maldonado, Enrique R."

Blockade of the mineralocorticoid receptor improves markers of human endothelial cell dysfunction and hematological indices in a mouse model of sickle cell disease by Rivera, Alicia, Vega, Christopher, Ramos‐Rivera, Arelys, Maldonado, Enrique R., Prado, Gregory N., Karnes, Hope E., Fesko, Yuri A., Snyder, L. Michael, Alper, Seth L., Romero, Jose R.

“…Increased endothelin‐1 (ET‐1) levels in patients with sickle cell disease (SCD) and transgenic mouse models of SCD contribute to disordered hematological,…”
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Aldosterone's Rapid, Nongenomic Effects Are Mediated by Striatin: A Modulator of Aldosterone's Effect on Estrogen Action by Coutinho, Patricia, Vega, Christopher, Pojoga, Luminita H, Rivera, Alicia, Prado, Gregory N, Yao, Tham M, Adler, Gail, Torres-Grajales, Manuel, Maldonado, Enrique R, Ramos-Rivera, Arelys, Williams, Jonathan S, Williams, Gordon, Romero, Jose R

“…The cellular responses to steroids are mediated by 2 general mechanisms: genomic and rapid/nongenomic effects. Identification of the mechanisms underlying…”
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Activation of the Mineralocorticoid Receptor Increases Striatin Levels by Pojoga, Luminita H., Coutinho, Patricia, Rivera, Alicia, Yao, Tham M., Maldonado, Enrique R., Youte, Rodeler, Adler, Gail K., Williams, Jonathan, Turchin, Alexander, Williams, Gordon H., Romero, Jose R.

“…Background: Aldosterone (ALDO), a critical regulator of sodium homeostasis, mediates its effects via activation of the mineralocorticoid receptor (MR) through…”
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274-OR: Beta-Cell Dysfunction Is Associated with Impaired Insulin-Mediated Suppression of Glucagon in Obese Hispanic Americans by CHEN, XI, MALDONADO CORCHADO, ENRIQUE R., MEROVCI, AURORA, CASE, EMINA, TRIPATHY, DEVJIT, DEFRONZO, RALPH A.

“…Recent studies have demonstrated an increase in the glucagon:insulin ratio in lean versus obese subjects. We assessed insulin-mediated suppression of plasma…”
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Mild Physiologic Hyperglycemia Induces Hepatic Insulin Resistance in Healthy Normal Glucose Tolerant Subjects–Role of Glucagon and Gluconeogenic Substrates by TRIPATHY, DEVJIT, MEROVCI, AURORA, CORCHADO, ENRIQUE R. MALDONADO, RITA, BASU, DEFRONZO, RALPH A.

“…The aim of the present study was to evaluate the effect of a physiologic increase in plasma glucose concentration on endogenous glucose production (EGP) in…”
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Abstract 170: Aldosterone Activates ex vivo Human Polymorphonuclear Leukocytes by Maldonado, Enrique R, Prado, Gregory N, Nieva, Adriana, Vazquez, Carlos, Saca, Gabriel, Rivera, Alicia, Romero, Jose R

“…Abstract only An important role for the mineralocorticoid receptor (MR) in vascular inflammation has been proposed. Polymorphonuclear (PMN) leukocytes are…”
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Abstract 363: Urinary Free Cortisol Variations in Essential Hypertension are Associated with Altered Glucocorticoid Receptor Binding in ex vivo Human Neutrophils by Chamarthi, Bindu, Pulido, Patricia, Nieva, Adriana, Prado, Gregory N, Maldonado, Enrique R, Torres-Grajales, Manuel, Williams, Gordon H, Rivera, Alicia, Romero, Jose R

“…Abstract only The role of cortisol in essential hypertension (HTN) is yet unclear. Urinary free cortisol (UFC) levels have been shown to be bimodally…”
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Mild Physiologic Hyperglycemia Impairs Beta-Cell Function and Induces Insulin Resistance in Healthy Normal Glucose Tolerant Subjects by MEROVCI, AURORA, MALDONADO CORCHADO, ENRIQUE R., TRIPATHY, DEVJIT, DEFRONZO, RALPH A.

“…The aim of the present study was to evaluate effect of a physiologic increase (+45 mg/dl) in plasma glucose concentration on insulin secretion in healthy NGT…”
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Stimulation of the Mineralocorticoid Receptor by Aldosterone Leads to Activation of HL-60 Neutrophils by Vazquez, Carlos E, Prado, Gregory N, Maldonado, Enrique R, Saca, Gabriela, Ortiz, Iren M, Brito, Giselle, Nieva, Adriana, Rivera, Alicia, Romero, Jose R

“…Abstract 3206 Blockade of the mineralocorticoid receptor (MR), the receptor for aldosterone (ALDO), improves cardiovascular morbidity and mortality. There is…”
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Endothelin-1 Receptor Antagonists Regulate Cell Surface-Associated Protein Disulfide Isomerase In Sickle Cell Disease by Prado, Gregory N, Alves, Jessica, Hernandez, Anna J, Maldonado, Enrique R, Youte, Rodeler, Romero, Jose R, Rivera, Alicia

“…Abstract 265 Erythrocyte hydration status and endothelial cell activation have been proposed as important contributors to vaso-occlusion and impaired blood…”
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Role of Connective Tissue Growth Factor In Endothelin-Mediated Endothelial Cell Activation by Hernandez, Anna J, Henriquez, Sonia, Maldonado, Enrique R, Youte, Rodeler, Prado, Gregory N, Coelho, Constanca, Rivera, Alicia, Romero, Jose R

“…Abstract 2107 Endothelial cell activation and elevated levels of circulating Endothelin-1 (ET-1) have been reported in patients with atherosclerosis and sickle…”
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