Search Results - "Maldonado, Elaina M"

Highly recruited brown adipose tissue does not in itself protect against obesity by von Essen, Gabriella, Lindsund, Erik, Maldonado, Elaina M., Zouhar, Petr, Cannon, Barbara, Nedergaard, Jan

“…The possibility to counteract the development of obesity in humans by recruiting brown or brite/beige adipose tissue (and thus UCP1) has attracted much…”
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Systems Biology Approaches Toward Understanding Primary Mitochondrial Diseases by Maldonado, Elaina M, Taha, Fatma, Rahman, Joyeeta, Rahman, Shamima

“…Primary mitochondrial diseases form one of the most common and severe groups of genetic disease, with a birth prevalence of at least 1 in 5000. These disorders…”
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Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease by Spanos, Christos, Maldonado, Elaina M, Fisher, Ciarán P, Leenutaphong, Petchpailin, Oviedo-Orta, Ernesto, Windridge, David, Salguero, Francisco J, Bermúdez-Fajardo, Alexandra, Weeks, Mark E, Evans, Caroline, Corfe, Bernard M, Rabbani, Naila, Thornalley, Paul J, Miller, Michael H, Wang, Huan, Dillon, John F, Quaglia, Alberto, Dhawan, Anil, Fitzpatrick, Emer, Moore, J Bernadette

“…Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. However, its molecular pathogenesis is incompletely characterized and…”
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Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease by Maldonado, Elaina M., Fisher, Ciarán P., Mazzatti, Dawn J., Barber, Amy L., Tindall, Marcus J., Plant, Nicholas J., Kierzek, Andrzej M., Moore, J. Bernadette

“…Non-alcoholic fatty liver disease (NAFLD) is a serious public health issue associated with high fat, high sugar diets. However, the molecular mechanisms…”
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Correction to: Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease by Spanos, Christos, Maldonado, Elaina M, Fisher, Ciarán P, Leenutaphong, Petchpailin, Oviedo-Orta, Ernesto, Windridge, David, Salguero, Francisco J, Bermúdez-Fajardo, Alexandra, Weeks, Mark E, Evans, Caroline, Corfe, Bernard M, Rabbani, Naila, Thornalley, Paul J, Miller, Michael H, Wang, Huan, Dillon, John F, Quaglia, Alberto, Dhawan, Anil, Fitzpatrick, Emer, Moore, J Bernadette

“…[This corrects the article DOI: 10.1186/s12953-018-0131-y.]…”
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Bi-allelic Variants in TKFC Encoding Triokinase/FMN Cyclase Are Associated with Cataracts and Multisystem Disease by Wortmann, Saskia B., Meunier, Brigitte, Mestek-Boukhibar, Lamia, van den Broek, Florence, Maldonado, Elaina M., Clement, Emma, Weghuber, Daniel, Spenger, Johannes, Jaros, Zdenek, Taha, Fatma, Yue, Wyatt W., Heales, Simon J., Davison, James E., Mayr, Johannes A., Rahman, Shamima

“…We report an inborn error of metabolism caused by TKFC deficiency in two unrelated families. Rapid trio genome sequencing in family 1 and exome sequencing in…”
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Integration of Genome Scale Metabolic Networks and Gene Regulation of Metabolic Enzymes With Physiologically Based Pharmacokinetics by Maldonado, Elaina M., Leoncikas, Vytautas, Fisher, Ciarán P., Moore, J. Bernadette, Plant, Nick J., Kierzek, Andrzej M.

“…The scope of physiologically based pharmacokinetic (PBPK) modeling can be expanded by assimilation of the mechanistic models of intracellular processes from…”
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